Hostname: page-component-78c5997874-m6dg7 Total loading time: 0 Render date: 2024-11-17T16:16:58.161Z Has data issue: false hasContentIssue false
  • English
  • Français

Five-year Outcome and Prognosis in Schizophrenia: A Report from the London Field Research Centre of the International Pilot Study of Schizophrenia

Published online by Cambridge University Press:  02 January 2018

R. Prudo  and
H. Munroe Blum
R. Prudo*
Affiliation:
Department of Psychiatry, McMaster University Medical Centre
H. Munroe Blum
Affiliation:
Department of Psychiatry, McMaster University Medical Centre
*
∗Department of Psychiatry, McMaster University Medical Centre, 1200 Main Street West, Hamilton, Ontario, Canada L8N 3Z5
Get access Rights & Permissions [Opens in a new window]

Abstract

A sample of 100 schizophrenic patients admitted to London area psychiatric hospitals were examined as part of the International Pilot Study of Schizophrenia. Clinical and social outcome were variable. At 5-year follow-up, 49% had good symptomatic outcome and 42%, good social outcome. Poor social functioning at inclusion was predictive of poor symptomatic outcome. Illness history (IH), occupational functioning (OF), social relationship functioning (SRF), negative and non-specific symptoms (NNS) at initial evaluation, and their interaction with sex and race accounted for 32% of the 5-year symptomatic outcome variance (n = 84; F=3.48; P<0.001). OF, SRF, housing status, NNS and their interaction with sex, race and age accounted for 47% of the social outcome variance (n = 62; F=2.62; P<0.007).

Type
Research Article
Information
The British Journal of Psychiatry , Volume 150 , Issue 3 , March 1987 , pp. 345 - 354
Copyright
Copyright © 1987 The Royal College of Psychiatrists 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Brown, G. W. (1962) The influence of family life on the course of schizophrenia. British Journal of Preventive Social Medicine, 16, 55.Google Scholar
Brown, & Birley, J. L. T. (1968) Crises and life changes and the onset of schizophrenia. Journal of Health and Social Behaviour, 9, 203–214.Google Scholar
Brown, , Bone, M., Dalison, B. & Wing, J. K. (1966) Schizophrenia and Social Care. London: Oxford University Press.Google Scholar
Brown, , Birley, J. L. T. & Wing, J. K. (1972) Influence of family life on the course of schizophrenic disorders: a replication. British Journal of Psychiatry, 121, 241–258.CrossRefGoogle ScholarPubMed
Fair Weather, G. W., Sanders, D. H., Maynard, H., et al (1969) Community Life for the Mentally III. Chicago: Aldine.Google Scholar
Hawk, A. B., Carpenter, W. T. Jr. & Strauss, J. S. (1975) Diagnostic criteria and five year outcome in schizophrenia: A report from the International Pilot Study of Schizophrenia. Archives of General Psychiatry, 32, 343–347.Google Scholar
Hemsi, L. K. (1967) Psychiatric morbidity of West Indian immigrants. Social Psychiatry, 2, 95–100.Google Scholar
Kolakowska, T., Williams, A. O., Ardern, M., Reveley, M. A., Jambor, K., Gelder, M. G. & Mandelbrote, B. M. (1985) Schizophrenia with good and poor outcome. I. Early clinical features, response to neuroleptics and signs of organic dysfunction. British Journal of Psychiatry, 146, 229–246.CrossRefGoogle ScholarPubMed
Lamb, H. R. (1978) Community Survival for Long-Term Patients. Washington: Jossey-Bass.Google Scholar
Langfeldt, G. (1956) The prognosis of schizophrenia. Acta Psychiatrica Neurologica Scandinavia, Suppl. 110.Google Scholar
Leff, J. & Vaughn, C. (1980) The interaction of life events and relatives' expressed emotion in schizophrenia and depressive neurosis. British Journal of Psychiatry, 136, 145–153.CrossRefGoogle ScholarPubMed
Leff, , Fisher, M. & Bertelsen, A. (1976) A cross-national epidemiological study of mania. British Journal of Psychiatry, 129, 428–442.CrossRefGoogle ScholarPubMed
Leff, , Kuipers, L., Berkowitz, R., Eberlein-Vries, R. & Sturgeon, D. (1982) A controlled trial of social intervention in the familites of schizophrenic patients. British Journal of Psychiatry, 141, 121–134.CrossRefGoogle Scholar
Mackay, A. V. P. (1980) Positive and negative schizophrenia symptoms and the role of dopamine. British Journal of Psychiatry, 137, 379.CrossRefGoogle ScholarPubMed
Pasamanick, B., Scarpitti, F. & Dinitz, S. (1967) Schizophrenics in the Community. New York: Appleton-Century-Croft.Google Scholar
Rwegellera, G. G. C. (1977) Psychiatric morbidity among West Africans and West Indians living in London. Psychological Medicine, 7, 317–329.CrossRefGoogle Scholar
Stein, L. I., Test, M. A. & Marx, A. J. (1975) Alternative to the Hospital: A Controlled Study. American Journal of Psychiatry, 132, 517–522.Google Scholar
Strauss, J. S. & Carpenter, W. T. Jr. (1974) The prediction of outcome in schizophrenia: II. Relationships between predictor and outcome variables. Archives of General Psychiatry, 31, 37–42.CrossRefGoogle ScholarPubMed
Strauss, J. S. & Carpenter, (1977) The prediction of outcome in schizophrenia: III. Five year outcome and its predictors. Archives of General Psychiatry, 34, 159–163.CrossRefGoogle ScholarPubMed
Vaillant, G. (1964) Prospective prediction of schizophrenia remission. Archives of General Psychiatry, 21, 509–515.CrossRefGoogle Scholar
Vaughn, C. E. & Leff, J. P. (1976) The influence of family and social factors on the course of psychiatric illness: A comparison of schizophrenic and depressed neurotic patients. British Journal of Psychiatry, 129, 125–137.Google Scholar
Vaughn, C. E. & Leff, J. P. (1981) Patterns of emotional response in relatives of schizophrenic patients. Schizophrenia Bulletin, 7, 43–45.Google Scholar
Wallace, C. J. (1980) A review and critique of social skills training with schizophrenic patients. Schizophrenia Bulletin, 6, 42.CrossRefGoogle ScholarPubMed
Wing, J. K., Cooper, J. E. & Sartorius, N. (1974) The Description and Classification of Psychiatric Symptoms: An Instruction Manual for the PSE and Catego System. London: Cambridge University Press.Google Scholar
World Health Organization (1965) International Classification of Diseases-Eighth Revision. Geneva: WHO.Google Scholar
World Health Organization (1973) International Pilot Study of Schizophrenia. Vol. 1, Geneva: WHO.Google Scholar
World Health Organization (1979) Schizophrenia: An International Follow-up Study, Vol. II. Geneva, WHO.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.