Hostname: page-component-78c5997874-s2hrs Total loading time: 0 Render date: 2024-11-18T18:54:16.713Z Has data issue: false hasContentIssue false

The Relationship between Alcoholism and Neurosis:

Evidence from a Twin Study

Published online by Cambridge University Press:  29 January 2018

M. J. Mullan
Affiliation:
Royal Free Hospital School of Medicine, Hampstead, London NW3 2QG
H. M. D. Gurling*
Affiliation:
Institute of Psychiatry, London SE5 8AF
B. E. Oppenheim
Affiliation:
Institute of Psychiatry, London SE5 8AF
R. M. Murray
Affiliation:
Institute of Psychiatry
*
Correspondence

Abstract

The twin register of the Maudsley Hospital was used to select a series of monozygotic (MZ) and same-sexed dizygotic (DZ) twins who had been given an ICD8 diagnosis related to alcoholism. They and their co-twins were traced. Medical and drinking histories were compiled (from records and by interview) for 56 twin-pairs, to permit current and retrospective diagnosis of any neurotic disorders. RDC diagnoses of panic disorder generalised anxiety disorder, obsessive–compulsive disorder and phobias were more common in the alcoholic probands and the co-twins who were also alcoholics than in the normal-drinking co-twins. The Eysenck Personality Questionnaire (EPQ) and the Severity of Alcohol Dependence Questionnaire (SADQ) were completed by 54 individuals. Neuroticism scores were significantly higher for both male and female alcoholics than for their normal-drinking co-twins; and intra-pair differences in neuroticism were significantly correlated with intra-pair differences in severity of dependence. These results suggest that both clinically diagnosed neurotic illness and high neuroticism scores are more often a consequence than a cause of alcoholism.

Type
Papers
Copyright
Copyright © 1986 The Royal College of Psychiatrists 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Barnes, G. (1979) The alcoholic personality. Journal of Studies on Alcohol, 40, 571634.Google Scholar
Caetano, R., Edwards, G., Oppenheim, A. N. & Taylor, C. (1978) Building a standardised alcoholism interview schedule. Drug and Alcohol Dependence, 3, 185197.Google Scholar
Edwards, G., Gross, M. M., Keller, M., Moser, J. & Room, R. (eds) (1977) Alcohol Related Disabilities, WHO Offset Publication No. 32. Geneva.Google Scholar
Emery, A. E. H. (1976) Methodology in Medical Genetics. Edinburgh: Churchill Livingstone.Google Scholar
Eysenck, H. J. & Eysenck, S. B. G. (1975) Manual of the Eysenck Personality Questionnaire. London: Hodder & Stoughton.Google Scholar
Eysenck, H. J. & Eysenck, S. B. G. (1976) Psychoticism as a Dimension of Personality. London: Hodder & Stoughton.Google Scholar
Freed, E. X. (1978) Alcohol and mood: An updated review. International Journal of the Addictions, 13, 173200.CrossRefGoogle ScholarPubMed
Gottesman, I. I. & Shields, J. (1972) Schizophrenia and genetics: A twin study vantage point. New York: Academic Press.Google Scholar
Gurling, H. M. D., Murray, R. M. & Clifford, C. A. (1981) Investigations into the genetics of alcohol dependence and into its effects on brain function. In Progress in Clinical and Biological (Twin Research Part 3c), (eds Gedda, L., Parisi, P. & Nance, W. E.). New York: Alan Liss.Google Scholar
Gurling, H. M. D., Reveley, M. A. & Murray, R. M. (1984a) Increased cerebral ventricular volume in monozygotic twins discordant for alcoholism. Lancet, i, 986988.Google Scholar
Gurling, H. M. D., Oppenheim, B. E. & Murray, R. M. (1984b) Depression, criminality and psychopathology associated with alcoholism: Evidence from a twin study. Acta Geneticae Medicae et Gemellologiae/Twin Research, 33(2), 333339.CrossRefGoogle ScholarPubMed
Koskenvuo, M., Langinvainio, H., Kaprio, J. & Sarna, S. (1984) Health–related psychosocial correlates of neuroticism. Fourth International Congress on Twin Studies. Acta Geneticae Medicae et Gemmellogiae/Twin Research, 33(2), 307320.Google Scholar
Loehlin, J. C. & Nichols, R. C. (1976) Heredity, Environment and Personality. Austin: University of Texas Press.Google Scholar
Loper, R. G., Kammeier, M. L. & Hoffman, H. (1973) MMPI characteristics of college freshman males who later became alcoholics. Journal of Abnormal Psychology, 82, 159162.CrossRefGoogle ScholarPubMed
Mello, N. K. (1972) Behavioural studies of alcoholism. In The Biology of Alcoholism, Vol. 2, (ed. Kissin, B. & Begleiter, H.). New York: Plenum.Google Scholar
Mullaney, J. & Trippett, C. J. (1979) Alcohol dependence and phobias. British Journal of Psychiatry, 135, 656673.Google Scholar
Orford, J. & Edwards, G. (1977) Alcoholism. Maudsley Monograph No. 26. London: Oxford University Press.Google Scholar
Shaw, D. M., MacSweeney, D. A., Johnson, A. L. & Merry, J. (1975) Personality characteristics of alcoholic and depressed patients. British Journal of Psychiatry, 126, 5659.Google Scholar
Shields, J. (1962) Monozygotic Twins Brought Up Apart and Brought Up Together. London: Oxford University Press.Google Scholar
Smail, P., Stockwell, T., Canter, S. & Hodgson, R. (1984) Alcohol dependence and phobic anxiety states. British Journal of Psychiatry, 144, 5357.Google Scholar
Spitzer, R. L., Endicott, J. & Robins, E. (1975) Research Diagnostic Criteria for a Selected Group of Functional Disorders, 2nd ed. New York: Biometric Research Division of the New York State Psychiatric Institute.Google Scholar
Stockwell, T., Hodgson, R. & Rankin, H. (1982) Tension reduction and the effects of prolonged alcohol consumption. British Journal of Addiction, 77, 6573.Google Scholar
Stockwell, T., Murphy, D. & Hodgson, R. (1983) The severity of alcohol dependence questionnaire: Its use, reliability and validity. British Journal of Addiction, 78, 145155.Google Scholar
Stockwell, T., Smail, P., Hodgson, R. & Canter, S. (1984) Alcohol dependence and phobic anxiety states. British Journal of Psychiatry, 144, 5863.Google Scholar
World Health Organisation (1965) International Classification of Diseases, 8th revision. Geneva: W.H.O. Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.