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Nasal eosinophilia in nasal smears of patients with persistent and intermittent allergic rhinitis

Published online by Cambridge University Press:  05 November 2018

G Berkiten ,
İ Aydoğdu ,
T L Kumral ,
Z Saltürk ,
Y Uyar ,
A Arslanoğlu ,
B Tutar  and
A E Göker
G Berkiten
Affiliation:
ENT Clinic, Okmeydanı Training and Research Hospital, Istanbul, Turkey
İ Aydoğdu
Affiliation:
ENT Clinic, Okmeydanı Training and Research Hospital, Istanbul, Turkey
T L Kumral
Affiliation:
ENT Clinic, Okmeydanı Training and Research Hospital, Istanbul, Turkey
Z Saltürk
Affiliation:
ENT Clinic, Okmeydanı Training and Research Hospital, Istanbul, Turkey
Y Uyar
Affiliation:
ENT Clinic, Okmeydanı Training and Research Hospital, Istanbul, Turkey
A Arslanoğlu
Affiliation:
ENT Clinic, Okmeydanı Training and Research Hospital, Istanbul, Turkey
B Tutar*
Affiliation:
ENT Clinic, Okmeydanı Training and Research Hospital, Istanbul, Turkey
A E Göker
Affiliation:
ENT Clinic, Okmeydanı Training and Research Hospital, Istanbul, Turkey
*
Author for correspondence: Dr Belgin Tutar, ENT Clinic, Okmeydanı Training and Research Hospital, Darülaceze cad. Şişli/Istanbul, Turkey E-mail: belgintutar@gmail.com
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Abstract

Background

Eosinophils are the principal effector cells involved in the pathogenesis of allergic rhinitis. Cell numbers increase in non-allergic rhinitis patients with eosinophilia, aspirin hypersensitivity and nasal polyposis, as well as in allergic rhinitis patients. Exfoliative nasal cytology can be used in the differential diagnosis of allergic rhinitis.

Objective

To evaluate nasal eosinophilia in nasal smears of patients with mild, persistent and intermittent allergic rhinitis.

Methods

The study comprised 60 patients with allergic rhinitis and 20 healthy volunteers. The patients were divided into intermittent and persistent allergic rhinitis groups. Nasal smear status, eosinophil numbers and Total Nasal Symptom Scores were compared.

Results

Nasal smear results were pathological in 40 of 60 allergic rhinitis patients, which was significantly higher than the rate in controls. The mean nasal eosinophilia score was significantly higher in the intermittent allergic rhinitis than in the persistent allergic rhinitis group (p = 0.029). There was a positive correlation between nasal eosinophilia score and Total Nasal Symptom Score (r = 0.652; p < 0.05) in persistent allergic rhinitis and intermittent allergic rhinitis patients.

Conclusion

The nasal smear test is inexpensive, objective and simple to perform, and should be part of the diagnostic investigation.

Keywords

EosinophiliaRhinitis, AllergicImmunoglobulin EAllergens
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 132 , Issue 11 , November 2018 , pp. 1018 - 1021
Copyright
Copyright © JLO (1984) Limited, 2018 

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Footnotes

Dr B Tutar takes responsibility for the integrity of the content of the paper

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