Hostname: page-component-78c5997874-s2hrs Total loading time: 0 Render date: 2024-11-18T19:23:26.605Z Has data issue: false hasContentIssue false

Dynamic Radiosurgery at the Toronto - Bayview Regional Cancer Centre, 1988-2007

Published online by Cambridge University Press:  02 December 2014

P. Davey*
Affiliation:
Department of Radiation Oncology, Ryerson University, Odette Cancer Centre
M. Schwartz
Affiliation:
Department of Neurosurgery, Sunnybrook Health Sciences Centre, University of Toronto, Toronto
P. O'Brien
Affiliation:
Unionville, Ontario, Canada
B. Gillies
Affiliation:
Department of Engineering, Department of Physics, Ryerson University, Odette Cancer Centre
*
Department of Radiation Oncology, University of Toronto, Odette Cancer Centre, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, Ontario, M4N 3M5, Canada. Email: phil.davey@sunnybrook.ca
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Dynamic radiosurgery was first developed in Montreal and was subsequently adopted at the Toronto-Bayview Regional Cancer Centre in 1988. At that time radiosurgery was in its infancy in Canada. The opportunity of offering highly conformal radiation treatments for intracranial targets presented numerous technical challenges notably in the area of quality assurance. This review chronicles the development of radiosurgery at the Toronto-Bayview Regional Cancer Centre and summarises the successes and failures of the program over the following two decades.

Type
Historical Review
Copyright
Copyright © The Canadian Journal of Neurological 2012

References

1Podgorsak, EB, Oliver, A, Pla, M, Lefebvre, PY, Hazel, J.Dynamic stereotactic radiosurgery. Int J Radiat Oncol Biol Phys. 1988;14 (1):11526.Google Scholar
2Davey, P.Radiobiology: nil desperandum. Br J Hosp Med. 1989;42 (3):20613.Google Scholar
3O’Brien, PF, Gillies, BA, Schwartz, ML, Young, C, Davey, P.Radiosurgery with unflattened 6-MV photon beams. Med Phys. 1991;18(3):51921.CrossRefGoogle ScholarPubMed
4Ramani, R, O’Brien, PF, Davey, P, et al.Implementation of multiple isocentre treatment for dynamic radiosurgery. Br J Radiol. 1995; 68(811):7315.Google Scholar
5Gillies, A, O’Brien, PF, McVittie, R, McParland, C, Easton, H.Engineering modifications for dynamic stereotactically assisted radiotherapy. Med Phys. 1993;20(5):14915B.Google Scholar
6Ramani, R, Ketko, MG, O’Brien, PF, Schwartz, ML.A QA phantom for dynamic stereotactic radiosurgery: Quantitative measurements. Med Phys. 1995;22(8):13436.Google Scholar
7Young, C, Summerfield, R, Schwartz, ML, O’Brien, P, Ramani, R.Radiosurgery for arteriovenous malformations: The University of Toronto experience. Can J Neurol Sci. 1997;24(2):99105.Google Scholar
8Schwartz, ML, Sixel, K, Young, CS, et al.Prediction of obliteration of arteriovenous malformations after radiosurgery: The obliteration prediction index (OPI). Can J Neurol Sci. 1997;24 (2):1069.Google Scholar
9Farb, RI, McGregor, C, Kim, JK, et al.Intracranial arteriovenous malformations: Real-time auto-triggered elliptic centric-ordered 3D gadolinium-enhanced MR angiography- Initial assessment. Radiology. 2001;220(1):24451.Google Scholar
10Andrade-Souza, YM, Zadeh, G, Scora, D, Tsao, MN, Schwartz, ML.Radiosurgery for basal ganglia, internal capsule, and thalamus arteriovenous malformation: clinical outcome. Neurosurgery. 2005;56(1):5664.Google Scholar
11Andrade-Souza, YM, Ramani, M, Scora, D, Tsao, MN, terBrugge, K, Schwartz, ML.Radiosurgical treatment for Rolandic arteriovenous malformations. J Neurosurg. 2006;105(5):68997.Google Scholar
12Andrade-Souza, YM, Zadeh, G, Ramani, M, Scora, D, Tsao, MN, Schwartz, ML.Testing the radiosurgery-based arteriovenous malformation score and the modified Spetzler-Martin grading system to predict radiosurgical outcome. J Neurosurg. 2005;103 (4):6428.Google Scholar
13Zadeh, G, Andrade-Souza, YM, Tsao, MN, et al.Pediatric arteriovenous malformation: University of Toronto experience using stereotactic radiosurgery. Childs Nerv Syst. 2007;23(2): 1959.Google Scholar
14Ramani, M, Andrade-Souza, YM, Dawson, DR, Scora, D, Tsao, MN, Schwartz, ML.Neurological deficit rather than obliteration determines quality of life in patients treated with radiosurgery for AVMs. In: Kondziolka, D, McDermott, M, Regis, J, Smee, R, Flickinger, JC, editors. Radiosurgery. Basel: Karger; 2006. p. 22838.Google Scholar
15Mirza-Aghazadeh, J, Yuri, M, Andrade-Souza, YM, et al.Radiosurgical retreatment for brain arteriovenous malformation. Can J Neurol Sci. 2006;33(2):18994.Google Scholar
16Andrade-Souza, YM, Ramani, M, Scora, D, Tsao, MN, terBrugge, K, Schwartz, ML.Embolization before radiosurgery reduces the obliteration rate of arteriovenous malformations. Neurosurgery. 2007;60(3):44352.Google Scholar
17Andrade-Souza, YM, Ramani, M, Beachey, DJ, et al.Liquid embolisation material reduces the delivered radiation dose: a physical experiment. Acta Neurochir. 2008;150(2):1614.Google Scholar
18da Costa, L, Thines, L, Dehdashti, AR, et al.Management and clinical outcome of posterior fossa arteriovenous malformations: report on a single-centre 15 year experience. J Neurol Neurosurg Psychiatry. 2009;80(4):3769.Google Scholar
19Dehdashti, AR, Thines, L, Willinsky, RA, ter Brugge, KG, Schwartz, ML, Wallace, MC.Multidisciplinary care of occipital arteriovenous malformations: effect on nonhemorrhagic headache, vision, and outcome in a series of 135 patients. J Neurosurg. 2010;113(4):7428.CrossRefGoogle Scholar
20Davey, P, O’Brien, P.Disposition of cerebral metastases from malignant melanoma: implications for radiosurgery. Neurosurgery. 1991;20(1):815.Google Scholar
21Davey, P, O’Brien, PF, Schwartz, ML, Cooper, PW.A phase I/II study of salvage radiosurgey. in the treatment of recurrent brain metastases. Br J Neurosurg. 1994;8:(6):71723.Google Scholar
22Shaw, E, Scott, C, Souhami, L, et al.Radiosurgery for the treatment of previously irradiated recurrent primary brain tumors and brain metastases: initial report of the radiation therapy oncology group protocol 90-05. Int J Radiat Oncol Biol Phys. 1996;34(3): 64754.Google Scholar
23Brenner, DF, Martel, MK, Hall, EJ.Fractionated regimens for stereotactic radiotherapy of recurrent tumors in the brain. Int J Radiat Oncol Biol Phys. 1991;21(3):81924.Google Scholar
24Davey, P, Schwartz, ML, Scora, D, Gardner, S, O’Brien, PF.Fractionated (split dose) radiosurgery in patients with recurrent brain metastases: implications for survival. Br J Neurosurg. 2007;21(5):4915.Google Scholar
25Sidhu, K, Cooper, P, Ramani, R, Schwartz, M, Franseen, E, Davey, P.Delineation of brain metastases on CT images for planning radiosurgery: concerns regarding accuracy. Br J Radiol. 2004;77 (913):3942.Google Scholar
26Stanford, J, Gardner, S, Schwartz, ML, Davey, P.Does the surgical resection of a brain metastases alter the planning and subsequent local control achieved with radiosurgery prescribed for recurrence at the operated site? Br J Neurosurg. 2011;25(4): 48891.Google Scholar
27Davey, P, Schwartz, M, Scora, D, Ennis, M, Smith, J.Fractionated radiosurgery for recurrent brain metastases: long term outcomes. Clin Oncol. 2011;23(3):S17.Google Scholar
28Szumacher, E, Schwartz, ML, Tsao, M, et al.Fractionated stereotactic radiotherapy for the treatment of vestibular schwannomas: combined experiences of the Toronto-Sunnybrook Regional Cancer Centre and the Princess Margaret Hospital. Int J Rad Oncol Bio Phys. 2002;53(4):98791.Google Scholar
29Davey, P, Schwartz, M, Young, C.Clinical indications for the radiosurgical treatment of brain tumors. Can J Oncol. 1994;4(3): 2736.Google Scholar