Hostname: page-component-78c5997874-xbtfd Total loading time: 0 Render date: 2024-11-18T12:19:23.319Z Has data issue: false hasContentIssue false
  • English
  • Français

Higher calcium urinary loss induced by a calcium sulphate-rich mineral water intake than by milk in young women

Published online by Cambridge University Press:  08 March 2007

Marion Brandolini ,
Léon Guéguen ,
Yves Boirie ,
Paulette Rousset ,
Marie-Claude Bertière  and
Bernard Beaufrère
Marion Brandolini*
Affiliation:
Unité du Métabolisme Protéino-Energétique, Université d'Auvergne/INRA, CRNH Auvergne, Clermont-Ferrand, France
Léon Guéguen
Affiliation:
INRA, Jouy-en-Josas, France
Yves Boirie
Affiliation:
Unité du Métabolisme Protéino-Energétique, Université d'Auvergne/INRA, CRNH Auvergne, Clermont-Ferrand, France
Paulette Rousset
Affiliation:
Unité du Métabolisme Protéino-Energétique, Université d'Auvergne/INRA, CRNH Auvergne, Clermont-Ferrand, France
Marie-Claude Bertière
Affiliation:
CERIN, Paris, France
Bernard Beaufrère
Affiliation:
Unité du Métabolisme Protéino-Energétique, Université d'Auvergne/INRA, CRNH Auvergne, Clermont-Ferrand, France
*
*Corresponding author: Marion Brandolini, fax +33 4 73 60 82 55, email brandol@clermont.inra.fr
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

It is well known that the intestinal availability of Ca from Ca-rich mineral waters is equivalent to that of milk Ca. However, the effect of associated anions on Ca urinary loss needs to be addressed. The aim of the current study was to compare, under ordinary conditions of consumption, milk and a SO4-rich mineral water as the Ca provider in a large number of subjects consuming the same quantity of Ca from the two sources in a crossover study lasting for an extended period. Thirty-seven healthy women completed a 12-week protocol, divided into four periods of 3 weeks (W). In the first (W1–3) and third (W6–9) periods, dietary Ca intake was restricted to 600 mg/d. In the second (W4–6) and final (W10–12) periods, either 400 ml/d medium-fat milk or 1 litre of a Ca- and SO4-rich mineral water, each providing about 480 mg Ca/d, was added to the diet in a random manner. Dietary evaluation, blood and urinary measures were performed during the last week (W6 and W12) of each Ca supplementation period. The urinary excretion of Ca was higher (0·5 mmol/d more) with water than with milk (P<0·001). An examination of all the dietary factors known to influence calciuria suggested that the acidogenic action of SO4 was responsible for this increased calciuria. Thus, despite an equal Ca intake and assuming an unchanged intestinal absorption, these results suggest that Ca balance is better with milk consumption than with CaSO4-rich water.

Keywords

MilkCa2SO4-rich mineral waterCalciuriaAcidogenic actionSulphates
Type
Research Article
Information
British Journal of Nutrition , Volume 93 , Issue 2 , February 2005 , pp. 225 - 231
Copyright
Copyright © The Nutrition Society 2005

References

Arnaud, M & Welsch, C (1976) Métabolisme et utilisation des sulfates dans les eaux minérales. Med Nutr 12, 21–28.Google Scholar
Bacciottini, L, Tanini, A, Falchetti, A, Masi, L, Franceschelli, F, Pampaloni, B, Giorgi, G & Brandi, ML (2004) Calcium bioavailability from a calcium-rich mineral water, with some observations on method. J Clin Gastroenterol 38, 761–766.Google Scholar
Barzel, US (1995) The skeleton as an ion exchange system: implications for the role of acid–base imbalance in the genesis of osteoporosis. J Bone Miner Res 10, 1431–1436.CrossRefGoogle ScholarPubMed
Buclin, T, Cosma, M, Appenzeller, M, Jacquet, AF, Decosterd, LA, Biollaz, J & Burckhardt, P (2001) Diet acids and alkalis influence calcium retention in bone. Osteoporos Int 12, 493–499.CrossRefGoogle ScholarPubMed
Cepollaro, C, Orlandi, G, Gonnelli, S, Ferrucci, G, Arditti, JC, Toti, E & Gennari, C (1996) Effect of calcium supplementation as a high-calcium mineral water on bone loss in early postmenopausal women. Calcif Tissue Int 59, 238–239.CrossRefGoogle Scholar
Couzy, F, Kastenmayer, P, Vigo, M, Clough, J, Munoz-Box, R & Barclay, DV (1995) Calcium bioavailability from a calcium- and sulfate-rich mineral water, compared with milk, in young adult women. Am J Clin Nutr 62, 1239–1244.CrossRefGoogle ScholarPubMed
Dawson-Hughes, B & Harris, SS (2002) Calcium intake influences the association of protein intake with rates of bone loss in elderly men and women. Am J Clin Nutr 75, 773–779.CrossRefGoogle ScholarPubMed
Favier, JC, Ireland-Ripert, J, Toque, C & Feinberg, M (1995) Répertoire général des aliments 2nd edn. Paris Inra-Cneva/Ciqual.Google Scholar
Frassetto, LA, Morris, RC, Jr Sebastian, A (2003) Diet-induced potassium-replete chloride sufficient chronic low-grade metabolic alkalosis as the naturally-selected optimal systemic acid–base state of humans-implications for bone health Nutritional Aspects of Osteoporosis Burckardt P Dawson-Hugues B Heaney RP Lausanne Academic Press abstract 30.Google Scholar
Frassetto, LA, Todd, KM, Morris, RC, Sebastian, A Jr. (1998) Estimation of net endogenous noncarbonic acid production in humans from dietary potassium and protein contents. Am J Clin Nutr 68, 576–583.Google Scholar
Green, TJ & Whiting, SJ (1994) Potassium bicarbonate reduces high protein-induced hypercalciuria in adult women. Nutr Res 1, 991–1002.Google Scholar
Guéguen, L (2001) Minerals and trace elements. In Nutritional Recommendations for the French Population, pp. 375–393 [A Martin, coordinator]. Sci Alim 21, 309–458.Google Scholar
Guéguen, L, Besançon, P (1972) Influence des sulfates sur le métabolisme phospho-calcique. I. Utilisation du sulfate de calcium par le mouton. Ann Biol Anim Biochim Biophys 12, 589–598.CrossRefGoogle Scholar
Guéguen, L & Pointillart, A (2000) The bioavailability of dietary calcium. J Am Coll Nutr 19 119S – 136SGoogle Scholar
Guillemant, J, Le HT, Accarie, C, Tézenas, du, Montcel, S, Delabroise, AM, Arnaud, MJ Guillemant, S (2000) Mineral water as a source of dietary calcium: acute effects on parathyroid function and bone resorption in young men. Am J Clin Nutr 71, 999–1002.CrossRefGoogle ScholarPubMed
Heaney, RP (1996) Calcium, In Principles of Bone Biology, pp. 1007–1018 [Bilezikian, JP, Raisz, GA & Rodan, GA, editors]. New York: Academic Press.Google Scholar
Heaney, RP & Dowell, MS (1994) Absorbability of the calcium in a high-calcium mineral water. Osteoporos Int 4, 323–324.Google Scholar
Heaney, RP & Recker, RR (1982) Effects of nitrogen, phosphorus, and caffeine on calcium balance in women. J Lab Clin Med 99, 46–55.Google ScholarPubMed
Heaney, RP & Recker, RR (1994) Determinants of endogenous fecal calcium in healthy women. J Bone Miner Res 9, 1621–1627.CrossRefGoogle ScholarPubMed
Heaney, RP, Smith, KT, Recker, RR & Hinders, SM (1989) Meal effects on calcium absorption. Am J Clin Nutr 49, 372–376.CrossRefGoogle ScholarPubMed
Hercberg, S, Deheeger, M & Preziosi, P (1994) SU.VI.MAX Portions AlimentairesGoogle Scholar
Itabashi, A, Takada, Y, Toba, Y, Ishida, H, Uenishi, K & Aoe, S (2003) Milk based protein increases bone mineral density and improves bone metabolism in human study. In Nutritional Aspects of Osteoporosis, abstract 34. [Burckhardt, P, Dawson-Hughes, B & Heaney, RP, editors]. Lausanne: Academic Press.Google Scholar
Jenvrin, C, Munoz, F, de la, Guéronnière, V, Garnero, P, Meunier PJ (2002) Consumption of a high calcium mineral water lowers biochemical indices of bone remodeling in postmenopausal women with low calcium intake. Osteoporos Int 13 Suppl. 1, S28Google Scholar
Kerstetter, JE, O'Brien, KO & Insogna, KL (2003) Dietary protein, calcium metabolism, and skeletal homeostasis revisited. Am J Clin Nutr 78 584S–592S.Google Scholar
Lemann J, Jr (1993) Urinary excretion of calcium, Mg and phosphorus. In Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 2nd edn. pp. 50–54 [Favus, MJ, editors]. New York: Raven Press.Google Scholar
Lemann, J Jr (1999) Relationship between urinary calcium and net acid excretion as determined by dietary protein and potassium: a review. Nephron 81 Suppl. 1, 18–25.CrossRefGoogle ScholarPubMed
Lemann, J, Jr, Gray, RW, Maierhofer, WJ Cheung, HS (1986) The importance of renal net acid excretion as a determinant of fasting urinary calcium excretion. Kidney Int 29, 743–746.Google Scholar
Le Moullec, N, Deheeger, M & Preziosi, P (1996) Validation du manuel-photos utilisé dans l'enquête alimentaire de l'étude SU.VI.MAX. Cah Nutr Diét 31, 158–164.Google Scholar
Massey, LK (1998) Does excess dietary protein adversely affect bone? Symposium overview. J Nutr 128, 1048–1050.CrossRefGoogle ScholarPubMed
Massey, LK (2003) Dietary animal and plant protein and human bone health: a whole foods approach. J Nutr 133, 862S–865S.Google Scholar
Pointillart, A, Guéguen, L (1993) Meal-feeding and phosphorus ingestion influence calcium bioavailability evaluated by calcium balance and bone breaking strength in pigs. Bone Miner 21, 75–81.CrossRefGoogle ScholarPubMed
Remer, T & Manz, F (1994) Estimation of the renal net acid excretion by adults consuming diets containing variable amounts of protein. Am J Clin Nutr 59, 1356–1361.Google Scholar
Remer, T, Dimitriou, T & Manz, F (2003) Dietary potential renal acid load and renal net acid excretion in healthy, free-living children and adolescents. Am J Clin Nutr 77, 1255–1260.Google Scholar
Roux, S, Baundoin, C, Boute, D, Brazier, M, De La, Gueronniere, V, De & Vernejoul, MC (2004) Biological effects of drinking-water. mineral consumption on calcium balance and bone remodeling markers. J Nutr Health Aging 8, 380–384.Google Scholar
Sebastian, A, Harris, ST, Ottaway, JH, Todd, KM & Morris, RCJ (1994) Improved mineral balance and skeletal metabolism in postmenopausal women treated with potassium bicarbonate. N Engl J Med 330, 1776–1781.Google Scholar
Sellmeyer, DE, Schloetter, M & Sebastian, A (2002) Potassium citrate prevents increased urine calcium excretion and bone resorption induced by a high sodium chloride diet. J Clin Endocrinol Metab 87, 2008–2012.Google Scholar
Spencer, H, Kramer, L, Rubio, N & Osis, D (1986) The effect of phosphorus on endogenous fecal calcium in man. Am J Clin Nutr 43, 844–851.CrossRefGoogle ScholarPubMed
Van Dokkum, W, de la, Guéronnière, V, Schaafsma, G, Bouley, C, Luten, J Latgé, C (1996) Bioavailability of calcium of fresh cheeses, enteral food and mineral water. A study with stable calcium isotopes in young adult women. Br J Nutr 75, 893–903.Google Scholar
Waldvogel, Abramowski, S, Arnaud, M, Aeschlimann, JM Burckhardt, P (2003) Bicarbonate rich mineral water inhibits bone resorption. In Nutritional Aspects of Osteoporosis, abstract 47. [Burckhardt, P, Dawson-Hugues, B, Heaney, RP, editors]. Lausanne: Academic Press.Google Scholar
Walser, M & Browder, AA (1959) Ion association. III. The effect of sulfate infusion on calcium excretion. J Clin Invest 38, 1404–1411.CrossRefGoogle ScholarPubMed
Whiting, SJ & Cole, DE (1986) Effect of dietary anion composition on acid-induced hypercalciuria in the adult rat. J Nutr 116, 388–394.Google Scholar
Whiting, SJ & Draper, HH (1980) The role of sulfate in the calciuria of high protein diets in adult rats. J Nutr 110, 212–222.Google Scholar
Wynckel, A, Hanrotel, C, Wuillai, A & Chanard, J (1997) Intestinal absorption from mineral water. Miner Electrolyte Metab 23, 88–92.Google ScholarPubMed