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Effect of butaphosphan and cyanocobalamin on postpartum metabolism and milk production in dairy cows

Published online by Cambridge University Press:  29 January 2013

R. A. Pereira ,
P. A. S. Silveira ,
P. Montagner ,
A. Schneider ,
E. Schmitt ,
V. R. Rabassa ,
L. F. M. Pfeifer ,
F. A. B. Del Pino ,
M. E. Pulga  and
M. N. Corrêa
R. A. Pereira*
Affiliation:
Núcleo de Pesquisa, Ensino e Extensão em Pecuária (NUPEEC), Departamento de Clínicas Veterinária, Universidade Federal de Pelotas, CEP: 96010-900, Pelotas, Rio Grande do Sul, Brazil
P. A. S. Silveira
Affiliation:
Núcleo de Pesquisa, Ensino e Extensão em Pecuária (NUPEEC), Departamento de Clínicas Veterinária, Universidade Federal de Pelotas, CEP: 96010-900, Pelotas, Rio Grande do Sul, Brazil
P. Montagner
Affiliation:
Núcleo de Pesquisa, Ensino e Extensão em Pecuária (NUPEEC), Departamento de Clínicas Veterinária, Universidade Federal de Pelotas, CEP: 96010-900, Pelotas, Rio Grande do Sul, Brazil
A. Schneider
Affiliation:
Núcleo de Pesquisa, Ensino e Extensão em Pecuária (NUPEEC), Departamento de Clínicas Veterinária, Universidade Federal de Pelotas, CEP: 96010-900, Pelotas, Rio Grande do Sul, Brazil
E. Schmitt
Affiliation:
Núcleo de Pesquisa, Ensino e Extensão em Pecuária (NUPEEC), Departamento de Clínicas Veterinária, Universidade Federal de Pelotas, CEP: 96010-900, Pelotas, Rio Grande do Sul, Brazil Centro de Pesquisa Agroflorestal de Rondônia – Embrapa CPAF, BR 364 - Km 5,5 - Zona Rural, Caixa Postal 127 - CEP 76815-800, Porto Velho, Rondônia, Brazil
V. R. Rabassa
Affiliation:
Núcleo de Pesquisa, Ensino e Extensão em Pecuária (NUPEEC), Departamento de Clínicas Veterinária, Universidade Federal de Pelotas, CEP: 96010-900, Pelotas, Rio Grande do Sul, Brazil
L. F. M. Pfeifer
Affiliation:
Núcleo de Pesquisa, Ensino e Extensão em Pecuária (NUPEEC), Departamento de Clínicas Veterinária, Universidade Federal de Pelotas, CEP: 96010-900, Pelotas, Rio Grande do Sul, Brazil Centro de Pesquisa Agroflorestal de Rondônia – Embrapa CPAF, BR 364 - Km 5,5 - Zona Rural, Caixa Postal 127 - CEP 76815-800, Porto Velho, Rondônia, Brazil
F. A. B. Del Pino
Affiliation:
Núcleo de Pesquisa, Ensino e Extensão em Pecuária (NUPEEC), Departamento de Clínicas Veterinária, Universidade Federal de Pelotas, CEP: 96010-900, Pelotas, Rio Grande do Sul, Brazil Departamento de Bioquímica, Universidade Federal de Pelotas, CEP: 96010-900, Pelotas, Rio Grande do Sul, Brazil
M. E. Pulga
Affiliation:
Bayer S. A. Animal Health, Rua Domingos Jorge, 1100 - Prédio 9701, CEP: 04779-900, São Paulo, SP, Brazil
M. N. Corrêa
Affiliation:
Núcleo de Pesquisa, Ensino e Extensão em Pecuária (NUPEEC), Departamento de Clínicas Veterinária, Universidade Federal de Pelotas, CEP: 96010-900, Pelotas, Rio Grande do Sul, Brazil
*
†E-mail: rubens_ap@yahoo.com.br
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Abstract

The aim of this study was to determine the effect of butaphosphan and cyanocobalamin (BTPC) supplementation on plasma metabolites and milk production in postpartum dairy cows. A total of fifty-two Holstein cows were randomly assigned to receive either: (1) 10 ml of saline (NaCl 0.9%, control group); (2) 1000 mg of butaphosphan and 0.5 mg of cyanocobalamin (BTPC1 group); and (3) 2000 mg of butaphosphan and 1.0 mg of cyanocobalamin (BTPC2 group). All cows received injections every 5 days from calving to 20 days in milk (DIM). Blood samples were collected every 15 days from calving until 75 DIM to determine serum concentration of glucose, non-esterified fatty acids (NEFA), β-hydroxybutyrate (BHB), cholesterol, urea, calcium (Ca), phosphorus (P), magnesium (Mg), aminotransferase aspartate (AST) and γ-glutamyltransferase (GGT). The body condition score (BCS) and milk production were evaluated from calving until 90 DIM. Increasing doses of BTPC caused a linear reduction in plasma concentrations of NEFA and cholesterol. Supplementation of BTPC also reduced concentrations of BHB but it did not differ between the two treatment doses. Milk yield and milk protein had a linear increase with increasing doses of BTPC. A quadratic effect was detected for milk fat and total milk solids according to treatment dose, and BTPC1 had the lowest mean values. Concentrations of glucose, urea, P, Mg, AST, GGT, milk lactose and BCS were not affected by treatment. These results indicate that injections of BTPC during the early postpartum period can reduce NEFA and BHB concentrations and increase milk production in Holstein cows.

Keywords

butaphosphancyanocobalaminpostpartum dairy cowsnon-esterified fatty acid
Type
Physiology and functional biology of systems
Information
animal , Volume 7 , Issue 7 , July 2013 , pp. 1143 - 1147
Copyright
Copyright © The Animal Consortium 2013 

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