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  • Print publication year: 2011
  • Online publication date: January 2012

Chapter 41 - Perioperativeantiemetic therapies

from Part 6 - IntravenousAnesthetics and Adjunct Drugs

Suggested readings

BaileyPL, StreisandJB, PaceNL, et al. Transdermal scopolamine reduces nausea and vomiting after outpatient laparoscopy. Anesthesiology 1990; 72:977–980.
ChangNS, SimoneAF, SchultheisLW. From the FDA: what's in a label? A guide for the anesthesia practitioner. Anesthesiology 2005; 103(1):179–185.
ChenJJ, FrameDG, WhiteTJ. Efficacy of ondansetron and prochlorperazine for the prevention of postoperative nausea and vomiting after total hip replacement or total knee replacement procedures: a randomized, double-blind, comparative trial. Arch Intern Med 1998; 158:2124–2128.
DiemunschP, SchoefflerP, BryssineB, et al. Antiemetic activity of the NK1 receptor antagonist GR205171 in the treatment of established postoperative nausea and vomiting after major gynaecological surgery. Br J Anaesth 1999; 82:274–276.
DominoKB, AndersonEA, PolissarNL, PosnerKL. Comparative efficacy and safety of ondansetron, droperidol, and metoclopramide for preventing postoperative nausea and vomiting: a meta-analysis. Anesth Analg 1999; 88:1370–1379.
ErnstE, PittlerMH. Efficacy of ginger for nausea and vomiting: a systematic review of randomized clinical trials. Br J Anaesth 2000; 84:367–371.
FortneyJT, GanTJ, GraczykS, et al. A comparison of the efficacy, safety, and patient satisfaction of ondansetron versus droperidol as antiemetics for elective outpatient surgical procedures: S3A-409 and S3A-410 Study Groups. Anesth Analg 1998; 86:731–738.
GanTJ, ApfelC, KovacA, et al. Aprepitant-PONV Study Group. A randomized, double-blind comparison of the NK1 antagonist, aprepitant versus ondansetron for the prevention of postoperative nausea and vomiting. Anesth Analg 2007; 104:1082–1089.
GanT, MeyersT, ApfelC. Consensus guidelines for managing postoperative nausea and vomiting. Anesth Analg 2003; 97:62–71.
GesztesiZ, ScuderiPE, WhitePF, et al. Substance P (Neurokinin-1) antagonist prevents postoperative vomiting after abdominal hysterectomy procedures. Anesthesiology 2000; 93:931–937.
GollV, OzanA, GreifR, et al. Ondansetron is no more effective than supplemental intraoperative oxygen for prevention of postoperative nausea and vomiting. Anesth Analg 2001; 92:112–117.
GreifR, LacinyS, RapfB, et al. Supplemental oxygen reduces the incidence of postoperative nausea and vomiting. Anesthesiology 1999; 91:1246–1252.
HarnettMJ, O'RourkeN, WalshM, et al. Transdermal scopolamine for prevention of intrathecal morphine-induced nausea and vomiting after cesarean delivery. Anesth Analg 2007; 105:764–769.
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HenziI, SondereggerJ, TramerMR. Systematic review: efficacy, dose-response, and adverse effects of droperidol for prevention of postoperative nausea and vomiting. Can J Anaesth 2000a; 47:537–551.
HenziJ, WalderB, TramerMR. Metoclopramide in the prevention of postoperative nausea and vomiting: a quantitative systematic review of randomized placebo-controlled studies. Br J Anaesth 1999; 83:761–771.
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KrankeP, MorinAM, RoewerN, EberhartLH. Dimenhydrinate for prophylaxis of postoperative nausea and vomiting: a metaanalysis of randomized controlled trials. Acta Anaesthesiol Scand 2002b; 46:238–244.
KreislerNS, SpiekermannBF, AscariCM, et al. Small-dose droperidol effectively reduces nausea in a general surgical adult patient population. Anesth Analg 2000; 91:1256–1261.
LeeA, DoneML. The use of nonpharmacologic techniques to prevent postoperative nausea and vomiting: a meta-analysis. Anesth Analg 1999; 88:1362–1369.
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LiuK, HsuCC, ChiaYY. The effective dose of dexamethasone for antiemesis after major gynecological surgery. Anesth Analg 1999; 89:1316–1318.
LoperKA, ReadyLB, DormanBH. Prophylactic transdermal scopolamine patches reduce nausea in postoperative patients receiving epidural morphine. Anesth Analg 1989; 68:144–146.
LorhanPH. Cyclizine lactate (marezine) for post operative control of nausea and vomiting after cataract surgery. Anesth Analg 1958; 37:247–248.
LudwinDB, ShaferSL. Con: the black box warning on droperidol should not be removed (but should be clarified!). Anesth Analg 2008; 106(5):1418–1420.
McKenzieR, WadhwaRK, UyNT, et al. Antiemetic effectiveness of intramuscular hydroxyzine compared with intramuscular droperidol. Anesth Analg 1981; 60:783–788.
MerritBA, OkyereCP, JasinskiDM. Isopropyl alcohol inhalation: alternative treatment of postoperative nausea and vomiting. Nurs Res 2002; 51:125–128.
MorinAM, BetzO, KrankeP, et al. Is ginger a relevant antiemetic for postoperative nausea and vomiting? Anasthesiol Intensivmed Notfallmed Schmerzther 2004; 39:281–285.
NaguibM, el BakryAK, KhoshimMH, et al. Prophylactic antiemetic therapy with ondansetron, tropisetron, granisetron and metoclopramide in patients undergoing laparoscopic cholecystectomy: a randomized, double-blind comparison with placebo. Can J Anaesth 1996; 43:226–231.
RappaportBA. FDA response to droperidol black box warning editorials. Anesth Analg 2008; 106(5):1585.
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TramerMR. A rational approach to the control of postoperative nausea and vomiting: evidence from systemic reviews. I. Efficacy and harm of antiemetic interventions, and methodological issues. Acta Anaesthesiol Scand 2001; 45:4–13.
TramerMR, ReynoldsDJM, MooreRA, McQuayHJ. Efficacy, dose-response, and safety of ondansetron in prevention of postoperative nausea and vomiting: a qualitative systematic review of randomized placebo-controlled trials. Anesthesiology 1997; 87:1277–1289.
WangJJ, HoST, LeeSC, et al. The use of dexamethasone for preventing postoperative nausea and vomiting in females undergoing thyroidectomy: a dose-ranging study. Anesth Analg 2000a; 91:1404–1407.
WangJJ, HoST, TzengJI, TangCS. The effect of timing of dexamethasone administration on its efficacy as a prophylactic antiemetic for postoperative nausea and vomiting. Anesth Analg 2000b; 91:136–139.
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YogendranS, AsokumarB, ChengDC, ChungF. A prospective randomized double-blinded study of the effect of intravenous fluid therapy on adverse outcomes on outpatient surgery. Anesth Analg 1995; 80:682–686.