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Redundant Complexity: A Critical Analysis of Intelligent Design in Biochemistry

Published online by Cambridge University Press:  01 April 2022

Niall Shanks  and
Karl H. Joplin
Niall Shanks
Affiliation:
Department of Philosophy, Department of Biological Sciences, East Tennessee State University
Karl H. Joplin
Affiliation:
Department of Biological Sciences, East Tennessee State University
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Abstract

Biological systems exhibit complexity at all levels of organization. It has recently been argued by Michael Behe that at the biochemical level a type of complexity exists—irreducible complexity—that cannot possibly have arisen as the result of natural, evolutionary processes and must instead be the product of (supernatural) intelligent design. Recent work on self-organizing chemical reactions calls into question Behe's analysis of the origins of biochemical complexity. His central interpretative metaphor for biochemical complexity, that of the well-designed mousetrap that ceases to function if critical parts are absent, is undermined by the observation that typical biochemical systems exhibit considerable redundancy and overlap of function. Real biochemical systems, we argue, manifest redundant complexity—a characteristic result of evolutionary processes.

Type
Research Article
Information
Philosophy of Science , Volume 66 , Issue 2 , June 1999 , pp. 268 - 282
Copyright
Copyright © 1999 by the Philosophy of Science Association

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Footnotes

†

Send requests for reprints to Dr. Niall Shanks, Department of Philosophy—Box 70656, East Tennessee State University, Johnson City, TN 37614 USA.

‡

We would like to thank George Gale for helpful comments, as well as the anonymous referees for Philosophy of Science.

References

Babloyantz, Agnessa (1986), Molecules, Dynamics and Life, New York: Wiley.Google Scholar
Behe, Michael J. (1996), Darwin's Black Box: The Biochemical Challenge to Evolution. New York: The Free Press.Google Scholar
Bennett, William S. Jr, and Steitz, Thomas A. (1978), “Glucose-induced Conformational Changes in Yeast Hexokinase”, Proceedings of the National Academy of Sciences, USA 75: 4848–4852.CrossRefGoogle ScholarPubMed
Beutler, Ernest (1993), “The Molecular Biology of G6PD Variants and other Red Cell Enzyme Defects”, Annual Review of Medicine 43: 47–59.CrossRefGoogle Scholar
Clayton, Rebecca A., White, Owen, Ketchum, Karen A., and Venter, J. Craig (1997), “The First Genome from the Third Domain of Life”, Nature 387: 459–462.10.1038/387459a0CrossRefGoogle ScholarPubMed
Cooke, Jonathan, Nowak, Martin A., Boerlijst, Maarten, and Maynard-Smith, John (1997), “Evolutionary Origins and Maintenance of Redundant Gene Expression during Metazoan Development”, Trends in Genetics 13: 360–364.CrossRefGoogle ScholarPubMed
Dowehower, Lawrence A., Harvey, Michele, Slagle, Betty L., McArthur, Mark J., Montgomery, Charles A. Jr., Butel, Janet S., and Bradley, Allan (1992), “Mice Deficient for p53 are Developmentally Normal but Susceptible to Spontaneous Tumors”, Nature 356: 215–221.CrossRefGoogle Scholar
Elledge, Richard M. and Lee, Wen-Hwa (1995), “Life and Death by p53”, BioEssays 17: 923–930.CrossRefGoogle ScholarPubMed
Goodwin, Brian (1996), How the Leopard Changed its Spots: The Evolution of Complexity. New York: Touchstone Books.Google Scholar
Gould, Steven J. and Vrba, Elizabeth S. (1982), “Exaptation—a Missing Term in the Science of Form”, Paleobiology 8: 4–5.CrossRefGoogle Scholar
Hess, Benno and Mikhailov, Alexander (1994), “Self-Organization in Living Cells”, Science 264: 223–224.CrossRefGoogle ScholarPubMed
Johnson, Phillip E. (1997), Defeating Darwinism by Opening Minds. Downers Grove, IL: InterVarsity Press.Google Scholar
Kauffman, Stuart (1993), The Origins of Order: Self Organization and Selection in Evolution. Oxford: Oxford University Press.Google Scholar
Martini, Giuseppe and Ursini, Matilde V. (1996), “A New Lease of Life for an Old Enzyme”, BioEssays 18: 631–637.CrossRefGoogle ScholarPubMed
Mitsialis, S. Alex and Kafatos, Fotis C. (1984), “Regulatory Elements Controlling Chorion Gene Expression are Conserved between Flies and Moths”, Nature 317: 453–456.CrossRefGoogle Scholar
Murray, Andrew W. and Hunt, Tim (1993), The Cell Cycle. Oxford: Oxford University Press.Google Scholar
Nicolis, Gregoire (1989), “Physics of Far-From-Equilibrium Systems and Self-Organization”, in Davis, P. (ed.) The New Physics. Cambridge: Cambridge University Press, 316–347.Google Scholar
Ralph, John, Mackay, John J., Hatfield, Ronald D., O'Malley, David M., Whetten, Ross W., and Sederoff, Ronald S. (1997), “Abnormal Lignin in a Loblolly Pine Mutant”, Science 277: 235–239.CrossRefGoogle Scholar
Smith, Emil L., Hill, Robert, Lehman, I. Robert, Lefkowski, Robert, Handler, Philip, and White, Abraham (1983), Principles of Biochemistry. New York: McGraw-Hill.Google Scholar
Tabony, James (1994), “Morphological Bifurcations involving Reaction-Diffusion Processes during Microtubule Formation”, Science 264: 245–248.CrossRefGoogle ScholarPubMed
Travis, John (1992), “Scoring a Technical Knockout in Mice”, Science 256:1392–1394.CrossRefGoogle ScholarPubMed
Tyson, John T. (1994), “What Everyone Should Know about the Belousov-Zhabotinsky Reaction”, in Levin, S. A. (ed.), Frontiers in Mathematical Biology. New York: Springer Verlag, 569–587.CrossRefGoogle Scholar
Voet, Donald, and Voet, Judith G. (1995), Biochemistry. New York: Wiley.Google Scholar
Vulliamy, Tom, Mason, Philip, and Luzzatto, Lucio (1992), “The Molecular Basis of Glucose-6-Phosphate Dehydrogenase Deficiency”, Trends in Genetics 8: 138–143.CrossRefGoogle ScholarPubMed
Winfree, Arthur T. (1984), “The Prehistory of the Belousov-Zhabotinsky Oscillator”, Journal of Chemical Education 61: 661–663.CrossRefGoogle Scholar
Winfree, Arthur T. (1994): “Puzzles about Excitable Media and Sudden Death”, in Levin, S. A. (ed.) Frontiers in Mathematical Biology. New York: Springer Verlag, 139–158.CrossRefGoogle Scholar