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Synthesis of gold nanoparticles specific to pH- and salt- tolerance for biomedical applications

Published online by Cambridge University Press:  22 February 2016

Prem C. Pandey  and
Govind Pandey
Prem C. Pandey*
Affiliation:
Department of Chemistry, Indian Institute of Technology (Banaras Hindu University), Varanasi-221005, India
Govind Pandey
Affiliation:
Department of Pharmacology, BRD Medical College, Gorakhpur-273013, India
*
*(Email: pcpandey.apc@itbhu.ac.in)
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Abstract

The synthesis of gold nanoparticles (AuNPs) displaying pH and salt resistant activity has been a challenging tasks. The use of aminopropyltrimethoxysilane (3-APTMS) as one of the reagent during the synthesis of AuNPs may control such activity due to its micellar behavior. The AuNPs made from 3-APTMS capped gold ions in the presence of formaldehyde are found insensitive to pH- and salt. The major findings on 3-APTMS and formaldehyde mediated synthesis of AuNPs reveal the following: (1) 3-APTMS being amphiphilic, dispersibility of as prepared AuNPs largely depends on the organic reducing agents. (2) An increase in the hydrocarbon content of the reducing agent facilitate the dispersibility of AuNPs in organic solvent whereas decrease of the same increases the dispersibility in water, (3) AuNPs made through aldehydic reducing agents (formaldehyde and acetaldehyde) have relatively better salt and pH tolerance as compared to ketonic reducing agents (acetone, t-butyl dimethyl ketone), and (4) an increase in 3-APTMS concentrations enables salt- and pH- resistant property to AuNPs irrespective of organic reducing agents.

Keywords

Autransmission electron microscopy (TEM)nanostructure
Type
Articles
Information
MRS Advances , Volume 1 , Issue 11: Nanomaterials and Synthesis , 2016 , pp. 729 - 735
Copyright
Copyright © Materials Research Society 2016 

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References

REFERENCES

Saha, K., Agasti, S.S., Kim, C., Li, X., and Rotello, V. M., Chem. Rev. 112, 2739 (2012).CrossRefGoogle Scholar
Pandey, P. C. and Chauhan, D. S., Analyst. 21, 137(2), 376 (2011).Google Scholar
Pandey, P. C., Pandey, A. and Pandey, G., J. Nanosci. Nanotech. 14, 6606 (2014)CrossRefGoogle Scholar
Pandey, P. C. and Pandey, G., J. Mater. Chemistry B. 2, 3383, (2014).CrossRefGoogle Scholar
Pandey, P. C., Pandey, D. and Pandey, G.., RSC Advances. 11, 579 (2011).Google Scholar
Leff, D. V., Brandt, L. and Heath, J. R, Langmuir, 12, 4723. (1996)CrossRefGoogle Scholar
Wight, A. P. and Davis, M. E., Chem. Rev. 102, 3589 (2002)CrossRefGoogle Scholar
Uppal, M. A., Kafisaz, A., Ewing, M. B. and Parkin, I. P.. Journal of Material chemistry A, 1, 7351 (2013)CrossRefGoogle Scholar
Turkevich, J., Gold Bulletin. 18, 86 (1985)CrossRefGoogle Scholar
Enustun, B. V. and Turkevich, J., J. Am. Chem. Soc. 85, 3317 (1963)CrossRefGoogle Scholar
London, F. Z., Phys. 63, 245 (1930)Google Scholar
Yang, H., Heng, X. and Hu, J. , RSC Adv., ,2, 12648 (2012)CrossRefGoogle Scholar
Zhang, X., Servos, M. R. and Liu, J, J. Am. Chem. Soc. 134, 9910 (2012)CrossRefGoogle Scholar
Su, K. H., Wei, Q. H., Zhang, X., Mock, J. J., Smith, D. R. and Schultz, S.. Nano Lett. 3, 1087 (2003)CrossRefGoogle Scholar
Srivastava, S., Frankamp, B. L. and Rotello, V. M.Chem. Mater. 17, 487 (2005).CrossRefGoogle Scholar