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Image-based 3D dosimetric studies with high dose rate intracavitary brachytherapy of cervical cancer

Published online by Cambridge University Press:  30 September 2019

N. Chakravarty ,
M. K. Semwal Open the ORCID record for M. K. Semwal [Opens in a new window] ,
G. Trivedi ,
V. Suhag ,
M. Jain ,
N. Sharma  and
R. S. Vashisth
N. Chakravarty
Affiliation:
Radiation Oncology Centre, Army Hospital (R&R), Delhi Cantonment, New Delhi110010, India
M. K. Semwal*
Affiliation:
Radiation Oncology Centre, Army Hospital (R&R), Delhi Cantonment, New Delhi110010, India
G. Trivedi
Affiliation:
Radiation Oncology Centre, Army Hospital (R&R), Delhi Cantonment, New Delhi110010, India
V. Suhag
Affiliation:
Radiation Oncology Centre, Army Hospital (R&R), Delhi Cantonment, New Delhi110010, India
M. Jain
Affiliation:
Radiation Oncology Centre, Army Hospital (R&R), Delhi Cantonment, New Delhi110010, India
N. Sharma
Affiliation:
Radiation Oncology Centre, Army Hospital (R&R), Delhi Cantonment, New Delhi110010, India
R. S. Vashisth
Affiliation:
Radiation Oncology Centre, Army Hospital (R&R), Delhi Cantonment, New Delhi110010, India
*
Author for correspondence: Dr M. K. Semwal, Radiation Oncology Centre, Army Hospital (R&R), Delhi Cantonment, New Delhi 110010, India. Tel: +91-11-25691181. Fax: +91-11-25693490. E-mail: manojsemwal@yahoo.co.in
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Abstract

Aim:

To study 2D and 3D dosimetric values for bladder and rectum, and the influence of bladder volume on bladder dose in high dose rate (HDR) intracavitary brachytherapy (ICBT). The large patient data incorporated in this study would better represent the inherent variations in many parameters affecting dosimetry in HDR-ICBT.

Material and Methods:

We prospectively collected data for 103 consecutive cervical cancer patients (over 310 HDR fractions) undergoing CT-based HDR-ICBT at our centre. Correlation among bladder and rectum maximum volume doses and corresponding International Commission on Radiation Units and Measurement (ICRU) point doses were estimated and analysed. Impact of bladder volume on bladder maximum dose was assessed.

Results:

The ICRU point doses to bladder and rectum varied from the volumetric doses to these organs. Further, bladder volume poorly correlated with bladder maximum dose for volume variations encountered in the clinical practice at our centre.

Findings:

ICRU point doses to bladder and rectum are less likely to correlate with long-term toxicities to these organs. Further, in clinical practice where inter-fraction bladder volume does not vary widely there is no correlation between bladder volume and bladder dose.

Keywords

bladder and rectum dosecervical cancerhigh dose rateintracavitary brachytherapy
Type
Original Article
Information
Journal of Radiotherapy in Practice , Volume 19 , Issue 3 , September 2020 , pp. 277 - 280
Copyright
© Cambridge University Press 2019

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