Hostname: page-component-78c5997874-4rdpn Total loading time: 0 Render date: 2024-11-19T09:32:57.576Z Has data issue: false hasContentIssue false
  • English
  • Français

Oncospheres of Taenia solium and T. saginata asiatica develop into metacestodes in normal and immunosuppressed mice

Published online by Cambridge University Press:  11 April 2024

I.C. Wang ,
Y.X. Ma ,
J.X. Guo ,
W.C. Chung ,
S.C. Lu ,
A. Ito  and
P.C. Fan
I.C. Wang
Affiliation:
Institute and Department of Parasitology, National Yangming University
Y.X. Ma
Affiliation:
Henan Provincial Health and Antiendemic Station
J.X. Guo
Affiliation:
Zhengzhou King-Shui Hospital, Zhengzhou, Henan, Peoples' Republic of China
W.C. Chung
Affiliation:
Department of Parasitology, Taipei Medical College
S.C. Lu
Affiliation:
Department of Parasitology, National Taiwan University, Taipei, Taiwan, Republic of China
A. Ito
Affiliation:
Department of Parasitology, Gifu University School of Medicine, Gifu, Japan
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Normal and immunosuppressed mice were infected with oncospheres of Taenia saginata asiatica and T. solium. Although normal ICR mice were not susceptible to these two parasites, cysticerci were recovered from the immunosuppressed ones following venous injection. For T. s. asiatica, immunosuppressed ICR mice had an infection rate of 12.5% and six cysticerci of this parasite were recovered from three males. After injection of T. solium oncospheres, a high infection rate of 57% was obtained and 23 cysticerci were collected from 13 male immunosuppressed ICR mice. The immunosuppressed C57 mice had the highest infection rate (100%) and cysticercus recovery rate (2.4%) for T. solium. The infection rate and cysticercus recovery rate in six normal C57 mice were 40% and 3% respectively. The immunosuppressed ICR, Balb/c and C3H mice were also susceptible to T. s. asiatica.

Type
Review Article
Information
Journal of Helminthology , Volume 73 , Issue 2 , February 1999 , pp. 183 - 186
Copyright
Copyright © Cambridge University Press 1999

References

Allan, J.C., Garcia-Dominguez, C., Craig, P.S., Rogan, M.T., Lowe, B.S. & Flisser, A. (1991) Sexual development of Taenia solium in hamsters. Annals of Tropical Medicine and Parasitology 85, 573–576.CrossRefGoogle ScholarPubMed
Dixon, J.B. & Jenkins, P. (1995) Immunology of mammalian metacestode infections. I. Antigens, protective immunity and immunopathology. Helminthological Abstracts 64, 533–542.Google Scholar
Fan, P.C., Lin, C.Y., Chen, C.C. & Chung, W.C. (1995) Morphological description of Taenia saginata asiatica (Cyclophyllidea: Taeniidae) from man in Asia. Journal of Helminthology 69, 299–303.CrossRefGoogle ScholarPubMed
Ishiwata, K., Oku, Y., Ito, M. & Kamiya, M. (1992) Responses to larval Taenia taeniaeformis in mice with severe combined immunodeficiency (scid). Parasitology 104, 363–369.CrossRefGoogle ScholarPubMed
Ito, A. (1985) Thymus dependency of induced immune responses against Hymenolepis nana (cestode) using congenitally athymic nude mice. Clinical and Experimental Immunology 60, 87–94.Google ScholarPubMed
Ito, A., Chung, W.C., Chen, C.C., Ito, M., Endo, S., Okamoto, M. & Fan, P.C. (1997a) Human Taenia eggs develop into cysticerci in scid mice. Parasitology 114, 85–88.CrossRefGoogle ScholarPubMed
Ito, A., Ito, M., Eom, K.S., Chung, W.C., Chen, C.C., Ma, L., Endo, S. & Fan, P.C. (1997b) In vitro hatched oncospheres of Asian Taenia from Korea and Taiwan develop into cysticerci in the peritoneal cavity of female scid (severe combined immunodeficiency) mice. International Journal for Parasitology 27, 631–633.CrossRefGoogle ScholarPubMed
Kamiya, M., Sato, H., Kitaoka, M., Ishiwata, K., Oku, Y., Ito, M. & Gathura, P. (1991) Laboratory rodent models for the tapeworm-stage of Taenia saginata and other related taeniid species. Southeast Asian Journal of Tropical Medicine and Public Health 22 (Supplement), 262–267.Google ScholarPubMed
Kitaoka, K., Oku, Y., Okamoto, M. & Kamiya, M. (1990) Development and sexual maturation of Taenia crassiceps (Cestoda) in the golden hamster. Journal of Parasitology 76, 399–402.CrossRefGoogle ScholarPubMed
Lucas, S.B., Hassounah, O.A., Muller, R. & Doenhoff, M. (1980) Abnormal development of Hymenolepis nana larvae in immunosuppressed mice. Journal of Helminthology 54, 75–82.CrossRefGoogle ScholarPubMed
Machnicka, B. & Smyth, J.D. (1985) The early development of larval Taenia saginata in vitro and in vivo . Acta Parasitolica Polonica 30, 47–52.Google Scholar
Mitchell, G.F., Goding, J.W. & Rickard, M.D. (1977) Studies on immune responses to larval cestodes in mice. Increased susceptibility of certain strains and hypothymic mice to Taenia taeniaeformis and analysis of passive transfer of resistance with serum. Australian Journal of Experimental Biology and Medical Science 55, 165–186.CrossRefGoogle ScholarPubMed
Stevenson, P. (1983) Observations on the hatching and activation of fresh Taenia saginata eggs. Annals of Tropical Medicine and Parasitology 77, 399–404.CrossRefGoogle ScholarPubMed
Wang, I.C., Ma, Y.X., Guo, J.X. & Fan, P.C. (1997) A comparative study on egg hatching methods and oncosphere viability determination for Taenia solium eggs. International Journal for Parasitology 27, 1311–1314.CrossRefGoogle ScholarPubMed
Yang, X., Xu, H., Cao, Z. & Wang, W. (1994) Establishment of mouse model for Cysticercus cellulosae. Chinese Journal of Parasitology and Parasitic Diseases 12, 297–299 (in Chinese with English summary).Google Scholar