Hostname: page-component-f554764f5-qhdkw Total loading time: 0 Render date: 2025-04-11T17:35:31.478Z Has data issue: false hasContentIssue false
  • English
  • Français

Relationship between neuropsychiatric symptoms, cognition, and neuroimaging in mild cognitive impairment: Are we there yet?

Commentary on “Neuropsychiatric symptoms and their neural correlates in individuals with mild cognitive impairment” by De Lucia et al.

Published online by Cambridge University Press:  23 February 2023

Latha Velayudhan
Latha Velayudhan*
Affiliation:
Division of Academic Psychiatry, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, UK South London and Maudsley NHS Foundation Trust, London, UK Department of Population Health Sciences, University of Leicester, Leicester, UK
*
Email: latha.velayudhan@kcl.ac.uk
Get access

Abstract

An abstract is not available for this content so a preview has been provided. Please use the Get access link above for information on how to access this content.
Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Commentary
Information
International Psychogeriatrics , Volume 35 , Special Issue 11: Issue Theme: Neuropsychiatric Symptoms of Mild and Major Neurocognitive Disorders , November 2023 , pp. 595 - 597
Copyright
© International Psychogeriatric Association 2023

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Article purchase

Temporarily unavailable

References

Bayard, S., Jacus, J. P., Raffard, S. and Gely-Nargeot, M. C. (2014). Apathy and emotion-based decision-making in amnesic mild cognitive impairment and Alzheimer’s disease. Behavioural Neurology, 2014, 231469.CrossRefGoogle ScholarPubMed
Beaudreau, S. A. and O'Hara, R. (2008). Late-life anxiety and cognitive impairment: a review. The American Journal of Geriatric Psychiatry, 16, 790–803.CrossRefGoogle ScholarPubMed
Brodaty, H. et al. (2012). Neuropsychiatric symptoms in older people with and without cognitive impairment. Journal of Alzheimer’s Disease, 31, 411–420.CrossRefGoogle ScholarPubMed
Connors, M. H., Teixeira-Pinto, A., Ames, D., Woodward, M. and Brodaty, H. (2023). Apathy and depression in mild cognitive impairment: distinct longitudinal trajectories and clinical outcomes. International Pyschogeriatrics, 1–10. https://doi.org/10.1017/S1041610222001089.Google ScholarPubMed
De Lucia, N. et al. (2023). Neuropsychiatric symptoms and their neural correlates in individuals with mild cognitive impairment. International Pyschogeriatrics, 1–10. https://doi.org/10.1017/S104161022200117X.Google ScholarPubMed
Fang, F., Gao, Y., Schulz, P. E., Selvaraj, S. and Zhang, Y. (2021). Brain controllability distinctiveness between depression and cognitive impairment. Journal of Affective Disorders, 294, 847–856.CrossRefGoogle ScholarPubMed
Folstein, M. F., Folstein, S. E. and McHugh, P. R. (1975). “Mini-mental state”. A practical method for grading the cognitive state of patients for the clinician. Journal of Psychiatric Research, 12, 189–198.CrossRefGoogle ScholarPubMed
Liu, C., Liu, S., Wang, X. and Ji, Y. (2021). Neuropsychiatric profiles in mild cognitive impairment with Lewy bodies. Aging & Mental Health, 25, 2011–2017.CrossRefGoogle ScholarPubMed
Lü, W., Duan, J., Zhang, W., Yang, W. and Yu, W. (2021). Relationship between neuropsychiatric symptoms and cognitive functions in patients with cognitive impairment. Psychogeriatrics, 21, 773–782.CrossRefGoogle ScholarPubMed
Martin, E. and Velayudhan, L. (2020). Neuropsychiatric symptoms in mild cognitive impairment: a literature review. Dementia and Geriatric Cognitive Disorders, 49, 146–155.CrossRefGoogle ScholarPubMed
Martin, J. L. and Ancoli-Israel, S. (2008). Sleep disturbances in long-term care. Clinics in Geriatric Medicine, 24, 39–50.CrossRefGoogle ScholarPubMed
Monastero, R., Mangialasche, F., Camarda, C., Ercolani, S. and Camarda, R. (2009). A systematic review of neuropsychiatric symptoms in mild cognitive impairment. Journal of Alzheimer’s Disease, 18, 11–30.10.3233/JAD-2009-1120CrossRefGoogle ScholarPubMed
Mortby, M. E. et al. (2022). Apathy as a treatment target in Alzheimer’s disease: implications for clinical trials. The American Journal of Geriatric Psychiatry, 30, 119–147.CrossRefGoogle ScholarPubMed
Nowrangi, M. A. et al. (2021). The association of neuropsychiatric symptoms with regional brain volumes from patients in a tertiary multi-disciplinary memory clinic. International Psychogeriatrics, 33, 233–244.CrossRefGoogle Scholar
Rosen, W. G., Mohs, R. C. and Davis, K. L. (1984). A new rating scale for Alzheimer’s disease. American Journal of Psychiatry, 141, 1356–1364.Google ScholarPubMed
Siafarikas, N. et al. (2021). Neuropsychiatric symptoms and brain morphology in patients with mild cognitive impairment and Alzheimer’s disease with dementia. International Psychogeriatrics, 33, 1217–1228.CrossRefGoogle ScholarPubMed
Sun, Y., Xu, W., Chen, K. L., Shen, X. N., Tan, L. and Yu, J. T. (2021). Mild behavioral impairment correlates of cognitive impairments in older adults without dementia: mediation by amyloid pathology. Translational Psychiatry, 11, 577.CrossRefGoogle ScholarPubMed
Velayudhan, L. (2023). Apathy and depression as risk factors for dementia conversion in mild cognitive impairment. International Psychogeriatrics, 1–7. https://doi.org/10.1017/S1041610223000042.Google ScholarPubMed
Zahodne, L. B., Gongvatana, A., Cohen, R. A., Ott, B. R. and Tremont, G. (2013). Are apathy and depression independently associated with longitudinal trajectories of cortical atrophy in mild cognitive impairment? The American Journal of Geriatric Psychiatry, 21, 1098–1106.CrossRefGoogle ScholarPubMed