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Antimicrobial resistance among salmonella isolates from hospitals in Rome

Published online by Cambridge University Press:  25 March 2010

Vincenzo Falbo ,
Alfredo Caprioli ,
Francesca Mondello ,
Maria Luisa Cacace ,
Stefania Luzi  and
Donato Greco
Vincenzo Falbo
Affiliation:
Laboratorio di Malattie Batteriche e Virali and Istituto Superiore di Sanità, Viale Regina Elena 299, 00161, Rome
Alfredo Caprioli
Affiliation:
Laboratorio di Malattie Batteriche e Virali and Istituto Superiore di Sanità, Viale Regina Elena 299, 00161, Rome
Francesca Mondello
Affiliation:
Laboratorio di Malattie Batteriche e Virali and Istituto Superiore di Sanità, Viale Regina Elena 299, 00161, Rome
Maria Luisa Cacace
Affiliation:
Laboratorio di Malattie Batteriche e Virali and Istituto Superiore di Sanità, Viale Regina Elena 299, 00161, Rome
Stefania Luzi
Affiliation:
Laboratorio di Epidemiologia e Biostatistica, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161, Rome
Donato Greco
Affiliation:
Laboratorio di Epidemiologia e Biostatistica, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161, Rome
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Summary

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The susceptibility to antimicrobial agents of 569 salmonella isolates collected in 1977–8 from patients in hospitals in Rome was tested. Fifty-nine per cent of all isolates were resistant to one or more antimicrobials. Resistance was most common to sulphathiazole, tetracycline, streptomycin, whereas colistin, gentamicin, tobramycin, trimethoprim-sulphamethoxazole and nalidixic acid were the most active in vitro.

Multiple resistance was most frequently found in strains of Salmonella wien and S. typhimurium (94% and 38% respectively).

A significant change in the resistance pattern of S. wien was observed between 1977 and 1978, with a significant increase of susceptibility to some antimicrobials in 1978.

Twenty-one R-plasmids transmissible to E. coli K12 were derived from 46 resistant strains of S. typhimurum.

Type
Research Article
Information
Journal of Hygiene , Volume 88 , Issue 2 , April 1982 , pp. 275 - 284
Copyright
Copyright © Cambridge University Press 1982

References

REFERENCES

Abbate, G. F., Alagia, T., d'Aprea, L., Leonessa, V. & Altucci, P. (1977). In vitro sensitivity to chemoantibiotics, displayed by recently isolated Salmonellae as indicator of the therapy of enteritides of which these microorganisms are the causative agents. Giornale di Malattie Infettive e Parassitarie 29, 221.Google Scholar
Altucci, P., Abbate, G. F., Alagia, I. & Leonessa, V. (1977). Salmonellae and salmonellosis in the view of our regional experience. Giornale di Malattie Infettive e Parassitarie 29, 553.Google Scholar
Anderson, E. S. & Lewis, M. J. (1965). Drug resistance and its transfer in Salmonella typhimurium. Nature 206, 579.CrossRefGoogle ScholarPubMed
Armitage, P. (1975). In Statistica Medico, p. 46. Feltrinelli.Google Scholar
Bauer, A. W., Kirby, W. M. M., Sherris, I. C. & Turck, M. (1966). Antibiotic susceptibility testing by a standardized single disc method. American Journal of Clinical Pathology 45, 493.CrossRefGoogle Scholar
Bissett, M. L., Abbott, S. L. & Wood, R. M. (1974). Antimicrobial resistance and R. factors in Salmonella isolated in California (1971–1972). Antimicrobial Agents and Chemotherapy 5, 161.CrossRefGoogle Scholar
Brisou, B., Bardon, A. & Menard, I. C. (1972). Salmonella wien dans la région toulonnaise. Médicine et Maladies Infectiuses 2, 173.CrossRefGoogle Scholar
Datta, N. & Hedges, R. W. (1972). Trimethoprim resistance conferred by W plasmids in Enterobacteriaceae. Journal of General Microbiology 72, 349.CrossRefGoogle Scholar
Dixon, W. I. (1975). In Biomedical Computer Programs P series, p. 259. University of California Press.Google Scholar
Duck, P. D., Dillon, J. R., Lior, H. & Eidus, L. (1978). Antibiotic resistance among predominant Salmonella serovare and phagovats in Canada. Canadian Journal of Microbiology 24, 1358.CrossRefGoogle Scholar
Edwards, P. R. & Ewing, W. H. (1973). Classification of Enterobacteriaceae. Burgess Publishing Co.Google Scholar
Grant, R. B. & Di Mambro, L. (1977). Antimicrobial resistance and resistance plasmids in Salmonella from Ontario, Canada. Canadian Journal of Microbiology 23, 1266.CrossRefGoogle ScholarPubMed
Kaufmann, F. (1966). The Bacteriology of Enterobacteriaceae. Copenhagen: Munksgaard.Google Scholar
Le Minor, S. (1972). Apparition en France d'une épidémie à Salmonella wien. Médecine et Maladies Infectieuses 2, 441.CrossRefGoogle Scholar
Luppi, A., Bucci, G., Maini, P., Gaiani, R. & Piva, I. (1973). Antibiotico-resistenza trasmissibile in stipiti di Salmonella, isolati in provincia di Ferrara, da feci umane, da liquami e da acque superficiali. Bollettino dell' Istituto Sieroterapico Milanese 52, 287.Google Scholar
Marks, M. I., Kazemi, M. & McKay, E. (1973). In vitro sensitivity of Salmonella to ten antimicrobial agents including sulfamethoxazole and trimethoprim, alone and in combination. Antimicrobial Agents and Chemotherapy 4, 555.CrossRefGoogle ScholarPubMed
Marranzano, M., Nastasi, A., Scarlata, G., Salvo, S. & Falcidia, A. (1976). Resistenza agli antibiotici e fattori di resistenza in stipiti di Salmonella wien isolati in Sicilia. Bollettino dell'Istituto Sieroterapico Milanese 55, 187.Google Scholar
McConnel, M. M., Smith, H. R., Leonardopoulos, J. & Anderson, E. S. (1979). The values of plasmid studies in the epidemiology of infections due to drug-resistant Salmonella wien. Journal of Infectious Diseases 139, 178.CrossRefGoogle Scholar
Mered, B., Benhassine, M., Papa, F., Kharti, B., Kheddari, M., Rahal, A. & Sari, L. (1970). Epidémie à S. wien et S. typhimurium dans un service de pédiatrie. Archives des Institus Pasteur d'Algérie 48, 41.Google Scholar
National Committee for Clinical Laboratory Standards (1975). Performance standards for disc susceptibility tests. Approved Standard Ash-2. NCCLS, 771 E. Lancaster Ave., Villanova, Pa 190085, U.S.A.Google Scholar
Neu, H. C., Cherubin, C. E., Longo, E. D., Flouton, B. & Winter, J. (1975). Antimicrobial resistance and R-factor transfer among isolates of Salmonella in the Northeastern United States: a comparison of human and animal isolates. Journal of Infectious Diseases 132, 617.CrossRefGoogle ScholarPubMed
Organisation Mondiale de la Santé (1978). La surveillance, moyen de prévenir et de réduire les risques pour la santé associés aux entérobactéries antibiorésistantes. Série de Rapports techniques, no. 624.Google Scholar
Paradelis, A. G. & Stathopoulos, G. (1978). Multi-resistant strains of Salmonella wien and Salmonella heidelberg susceptible to cephradine. Journal of Antimicrobial Chemotherapy 4, 386.CrossRefGoogle ScholarPubMed
Pitzus, E., Peretti, P., Ghinelli, P. & Bisicchia, S. (1975). Considerazioni sull'attività (CMI) rivelata su 247 sierotipi di Salmonella. Bollettino dell'Istituto Sieroterapico Milanese, 54, 488.Google Scholar
Pocurull, D. W., Gaines, S. A. & Mercer, H. D. (1971). Surveys of infectious multiple drug resistance among Salmonella isolated from animals in the United States. Applied Microbiology 21, 358.CrossRefGoogle ScholarPubMed
Schroeder, S. A., Terry, P. M. & Bennett, J. V. (1968). Antibiotic resistance and transfer factor in Salmonella, United States 1967. Journal of the American Medical Association 205, 903.CrossRefGoogle ScholarPubMed
Voogd, C. E., Guinée, P. A. M., Manten, A. & Valkenburg, J. J. (1973). Incidence of resistance to tetracycline, chloramphenicol and ampicillin among Salmonella species isolated in the Netherlands in 1969, 1970 and 1971. Antonie van Leeuwenhoek 39, 321.CrossRefGoogle ScholarPubMed
Voogd, C. E., Van Leeuwen, W. J., Guinée, P. A. M., Manten, A. & Valkenburg, J. J. (1977). Incidence of resistance to ampicillin, chloramphenicol, kanamycin and tetracycline among Salmonella species isolated in the Netherlands in 1972, 1973 and 1974. Antonie van Leeuwenhoek 43, 269.CrossRefGoogle ScholarPubMed
Winshell, E. B., Cherubin, C., Winter, J. & Neu, H. C. (1970). Antibiotic resistance of Salmonella in the Eastern United States. Antimicrobial Agents and Chemotherapy 1969, 86.Google Scholar