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Antimicrobial resistance among salmonella isolates from hospitals in Rome

  • Vincenzo Falbo (a1), Alfredo Caprioli (a1), Francesca Mondello (a1), Maria Luisa Cacace (a1), Stefania Luzi (a2) and Donato Greco (a2)...

Summary

The susceptibility to antimicrobial agents of 569 salmonella isolates collected in 1977–8 from patients in hospitals in Rome was tested. Fifty-nine per cent of all isolates were resistant to one or more antimicrobials. Resistance was most common to sulphathiazole, tetracycline, streptomycin, whereas colistin, gentamicin, tobramycin, trimethoprim-sulphamethoxazole and nalidixic acid were the most active in vitro.

Multiple resistance was most frequently found in strains of Salmonella wien and S. typhimurium (94% and 38% respectively).

A significant change in the resistance pattern of S. wien was observed between 1977 and 1978, with a significant increase of susceptibility to some antimicrobials in 1978.

Twenty-one R-plasmids transmissible to E. coli K12 were derived from 46 resistant strains of S. typhimurum.

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References

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