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Antimicrobial resistance among salmonella isolates from hospitals in Rome

Published online by Cambridge University Press:  25 March 2010

Vincenzo Falbo ,
Alfredo Caprioli ,
Francesca Mondello ,
Maria Luisa Cacace ,
Stefania Luzi  and
Donato Greco
Vincenzo Falbo
Affiliation:
Laboratorio di Malattie Batteriche e Virali and Istituto Superiore di Sanità, Viale Regina Elena 299, 00161, Rome
Alfredo Caprioli
Affiliation:
Laboratorio di Malattie Batteriche e Virali and Istituto Superiore di Sanità, Viale Regina Elena 299, 00161, Rome
Francesca Mondello
Affiliation:
Laboratorio di Malattie Batteriche e Virali and Istituto Superiore di Sanità, Viale Regina Elena 299, 00161, Rome
Maria Luisa Cacace
Affiliation:
Laboratorio di Malattie Batteriche e Virali and Istituto Superiore di Sanità, Viale Regina Elena 299, 00161, Rome
Stefania Luzi
Affiliation:
Laboratorio di Epidemiologia e Biostatistica, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161, Rome
Donato Greco
Affiliation:
Laboratorio di Epidemiologia e Biostatistica, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161, Rome
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Summary

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The susceptibility to antimicrobial agents of 569 salmonella isolates collected in 1977–8 from patients in hospitals in Rome was tested. Fifty-nine per cent of all isolates were resistant to one or more antimicrobials. Resistance was most common to sulphathiazole, tetracycline, streptomycin, whereas colistin, gentamicin, tobramycin, trimethoprim-sulphamethoxazole and nalidixic acid were the most active in vitro.

Multiple resistance was most frequently found in strains of Salmonella wien and S. typhimurium (94% and 38% respectively).

A significant change in the resistance pattern of S. wien was observed between 1977 and 1978, with a significant increase of susceptibility to some antimicrobials in 1978.

Twenty-one R-plasmids transmissible to E. coli K12 were derived from 46 resistant strains of S. typhimurum.

Type
Research Article
Information
Journal of Hygiene , Volume 88 , Issue 2 , April 1982 , pp. 275 - 284
Copyright
Copyright © Cambridge University Press 1982

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