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A Comparative Study on Virology, Epidemiology, and Clinical Features of SARS and COVID-19

Published online by Cambridge University Press:  31 August 2021

Yanmei Zhao
Affiliation:
Institute of Disaster and Emergency Medicine, Tianjin University, Nankai District, Tianjin, P.R. China
Qianying Lu
Affiliation:
Institute of Disaster and Emergency Medicine, Tianjin University, Nankai District, Tianjin, P.R. China
Xiangyan Meng
Affiliation:
Institute of Disaster and Emergency Medicine, Tianjin University, Nankai District, Tianjin, P.R. China
Siyu Huang
Affiliation:
Institute of Disaster and Emergency Medicine, Tianjin University, Nankai District, Tianjin, P.R. China
Jianfeng Zhang
Affiliation:
Institute of Disaster and Emergency Medicine, Tianjin University, Nankai District, Tianjin, P.R. China
Wenlong Dong
Affiliation:
Institute of Disaster and Emergency Medicine, Tianjin University, Nankai District, Tianjin, P.R. China
Haojun Fan*
Affiliation:
Institute of Disaster and Emergency Medicine, Tianjin University, Nankai District, Tianjin, P.R. China
Shike Hou*
Affiliation:
Institute of Disaster and Emergency Medicine, Tianjin University, Nankai District, Tianjin, P.R. China
*
Corresponding author: Haojun Fan, Email: fanhaojun999@126.com; Shike Hou, Email: houshike@126.com
Corresponding author: Haojun Fan, Email: fanhaojun999@126.com; Shike Hou, Email: houshike@126.com

Abstract

In December 2019, an outbreak of an unknown cause of pneumonia (later named coronavirus disease 2019 [COVID-19]) occurred in Wuhan, China. This was found to be attributed to a novel coronavirus of zoonotic origin, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2; previously named 2019 novel coronavirus or 2019-nCoV). The SARS-CoV-2, a new type of highly pathogenic human coronavirus related to severe acute respiratory syndrome coronavirus (SARS-CoV), spread rapidly worldwide and caused 246,303,023 confirmed infections, including 4,994,160 deaths, by October 31, 2021. SARS-CoV-2 and SARS-CoV vary in their specific characteristics, regarding epidemics and pathogenesis. This article focuses on the comparison of the virology, epidemiology, and clinical features of SARS-CoV and SARS-CoV-2 to reveal their common and distinct properties, to provide an up-to-date resource for the development of advanced systems and strategies to monitor and control future epidemics of highly pathogenic human coronaviruses.

Type
Commentary
Copyright
© The Author(s), 2021. Published by Cambridge University Press on behalf of Society for Disaster Medicine and Public Health, Inc

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