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An epidemiological study of paediatric pulmonary hypertension in Turkey

Published online by Cambridge University Press:  19 June 2015

Ayhan Pektas ,
Bilgehan M. Pektas  and
Serdar Kula
Ayhan Pektas*
Affiliation:
Department of Pediatric Cardiology, Afyon Kocatepe University Medical School Hospital, Afyonkarahisar, Turkey
Bilgehan M. Pektas
Affiliation:
Department of Pharmacology, Afyon Kocatepe University Medical School, Afyonkarahisar, Turkey
Serdar Kula
Affiliation:
Department of Pediatric Cardiology, Gazi University Medical School Hospital, Ankara, Turkey
*
Correspondence to: A. Pektas, MD, Selcuklu Mah., Adnan Kahveci Cad. No: 16/2 03128, Afyonkarahisar 03200, Turkey. Tel: +90 272 246 3333; Fax: +90 272 246 3322; E-mail: drayhanpektas@hotmail.com
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Abstract

Objective

The present study aims to evaluate the epidemiological characteristics of paediatric pulmonary hypertension within the entire Turkish population over a period of 5 years using the registry of the National Health Insurance System.

Methods

All individuals aged <18 years who were admitted to a Turkish hospital for the first time between 2009 and 2013 with a discharge diagnosis of idiopathic pulmonary hypertension and secondary pulmonary hypertension were identified.

Results

The overall annual incidence of idiopathic pulmonary hypertension during childhood was 11.7 cases/million, whereas the overall annual incidence of secondary pulmonary hypertension during childhood was 9.5 cases/million. There was a gradual and significant increase in the annual incidence of idiopathic pulmonary hypertension and that of secondary pulmonary hypertension during the 5-year study period (p=0.001 for both). In the years 2012 and 2013, idiopathic pulmonary hypertension was significantly more frequent in children aged <2 years when compared with children aged above 2 years (p=0.002 for both). The male to female ratio was 1.2:1 for idiopathic pulmonary hypertension, whereas the female to male ratio was 1.1:1 for secondary pulmonary hypertension during childhood.

Conclusion

The incidence of paediatric pulmonary hypertension in Turkey is higher than those reported for the Western populations. Moreover, no female dominance could be observed. These discrepancies may be attributed to the differences in the study design, study cohort, timing of the study, and the definitions adopted for pulmonary hypertension classification.

Keywords

Epidemiologypaediatricincidencepulmonary hypertension
Type
Original Articles
Information
Cardiology in the Young , Volume 26 , Issue 4 , April 2016 , pp. 693 - 697
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Copyright
© Cambridge University Press 2015 

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