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Drugs as instruments from a developmental child and adolescent psychiatric perspective

Published online by Cambridge University Press:  10 November 2011

Tobias Banaschewski ,
Dorothea Blomeyer ,
Arlette F. Buchmann ,
Luise Poustka ,
Aribert Rothenberger  and
Manfred Laucht
Tobias Banaschewski
Affiliation:
Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, 68159 Mannheim, Germany. tobias.banaschewski@zi-mannheim.dedorothea.blomeyer@zi-mannheim.dearlette.buchmann@zi-mannheim.deluise.poustka@zi-mannheim.demanfred.laucht@zi-mannheim.dewww.zi-mannheim.de
Dorothea Blomeyer
Affiliation:
Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, 68159 Mannheim, Germany. tobias.banaschewski@zi-mannheim.dedorothea.blomeyer@zi-mannheim.dearlette.buchmann@zi-mannheim.deluise.poustka@zi-mannheim.demanfred.laucht@zi-mannheim.dewww.zi-mannheim.de
Arlette F. Buchmann
Affiliation:
Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, 68159 Mannheim, Germany. tobias.banaschewski@zi-mannheim.dedorothea.blomeyer@zi-mannheim.dearlette.buchmann@zi-mannheim.deluise.poustka@zi-mannheim.demanfred.laucht@zi-mannheim.dewww.zi-mannheim.de
Luise Poustka
Affiliation:
Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, 68159 Mannheim, Germany. tobias.banaschewski@zi-mannheim.dedorothea.blomeyer@zi-mannheim.dearlette.buchmann@zi-mannheim.deluise.poustka@zi-mannheim.demanfred.laucht@zi-mannheim.dewww.zi-mannheim.de
Aribert Rothenberger
Affiliation:
Department of Child and Adolescent Psychiatry and Psychotherapy, University of Göttingen, 37075 Göttingen, Germany. arothen@gwdg.de
Manfred Laucht
Affiliation:
Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, 68159 Mannheim, Germany. tobias.banaschewski@zi-mannheim.dedorothea.blomeyer@zi-mannheim.dearlette.buchmann@zi-mannheim.deluise.poustka@zi-mannheim.demanfred.laucht@zi-mannheim.dewww.zi-mannheim.de
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Abstract

Developmental, epidemiological, and neurobiological studies indicate that the adaptive and maladaptive functions, as well as immediate and long-term consequences of drug use, may vary by age. Early initiation seems to be associated with a reduced ability to use drugs purposely in a temporally stable, non-addictive manner. Prevention strategies should consider social environmental factors and aim to delay age at initiation.

Type
Open Peer Commentary
Information
Behavioral and Brain Sciences , Volume 34 , Issue 6 , December 2011 , pp. 312 - 313
Copyright
Copyright © Cambridge University Press 2011

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References

Adriani, W., Spijker, S., Deroche-Gamonet, V., Laviola, G., Le Moal, M., Smit, A. B. & Piazza, P. V. (2003) Evidence for enhanced neurobehavioral vulnerability to nicotine during periadolescence in rats. The Journal of Neuroscience 23(11):4712–16.Google Scholar
Andersen, S. L. & Teicher, M. H. (2009) Desperately driven and no brakes: Developmental stress exposure and subsequent risk for substance abuse. Neuroscience and Biobehavioral Reviews 33(4):516–24.Google Scholar
Behrendt, S., Wittchen, H. U., Hofler, M., Lieb, R. & Beesdo, K. (2009) Transitions from first substance use to substance use disorders in adolescence: Is early onset associated with a rapid escalation? Drug and Alcohol Dependence 99(1–3):68–78.CrossRefGoogle ScholarPubMed
Belin, D., Mar, A. C., Dalley, J. W., Robbins, T. W. & Everitt, B. J. (2008) High impulsivity predicts the switch to compulsive cocaine-taking. Science 320:1352–55.Google Scholar
Blomeyer, D., Buchmann, A. F., Schmid, B., Jennen-Steinmetz, C., Schmidt, M. H., Banaschewski, T. & Laucht, M. (2011) Age at first drink moderates the impact of current stressful life events on drinking behavior in young adults. Alcoholism, Clinical and Experimental Research 35(6):1142–48.Google Scholar
Blomeyer, D., Treutlein, J., Esser, G., Schmidt, M. H., Schumann, G. & Laucht, M. (2008) Interaction between CRHR1 gene and stressful life events predicts adolescent heavy alcohol use. Biological Psychiatry 63(2):146–51.Google Scholar
Brown, S. A. & Tapert, S. F. (2004) Adolescence and the trajectory of alcohol use: Basic to clinical studies. Annals of the New York Academy of Sciences 1021:234–44.CrossRefGoogle ScholarPubMed
Buchmann, A. F., Schmid, B., Blomeyer, D., Becker, K., Treutlein, J., Zimmermann, U. S., Jennen-Steinmetz, C., Schmidt, M. H., Esser, G., Banaschewski, T., Rietschel, M., Schumann, G. & Laucht, M. (2009) Impact of age at first drink on vulnerability to alcohol-related problems: Testing the marker hypothesis in a prospective study of young adults. Journal of Psychiatric Research 43(15):1205–12.CrossRefGoogle Scholar
Buchmann, A. F., Schmid, B., Blomeyer, D., Zimmermann, U. S., Jennen-Steinmetz, C., Schmidt, M. H., Esser, G., Banaschewski, T., Mann, K. & Laucht, M. (2010) Drinking against unpleasant emotions: Possible outcome of early onset of alcohol use? Alcoholism, Clinical and Experimental Research 34(6):1052–57.Google Scholar
Casey, B. J. & Jones, R. M. (2010) Neurobiology of the adolescent brain and behavior: Implications for substance use disorders. Journal of the American Academy of Child and Adolescent Psychiatry 49(12):1189–201.Google ScholarPubMed
DeWit, D. J., Adlaf, E. M., Offord, D. R. & Ogborne, A. C. (2000) Age at first alcohol use: A risk factor for the development of alcohol disorders. American Journal of Psychiatry 157(5):745–50.Google Scholar
Doremus-Fitzwater, T. L., Varlinskaya, E. I. & Spear, L. P. (2010) Motivational systems in adolescence: Possible implications for age differences in substance abuse and other risk-taking behaviors. Brain and Cognition 72(1):114–23.CrossRefGoogle ScholarPubMed
Grant, B. F. & Dawson, D. A. (1997) Age at onset of alcohol use and its association with DSM-IV alcohol abuse and dependence: Results from the National Longitudinal Alcohol Epidemiologic Survey. Journal of Substance Abuse 9:103–10.Google Scholar
Kendler, K. S., Schmitt, E., Aggen, S. H. & Prescott, C. A. (2008) Genetic and environmental influences on alcohol, caffeine, cannabis, and nicotine use from early adolescence to middle adulthood. Archives of General Psychiatry 65(6):674–82.CrossRefGoogle ScholarPubMed
Laucht, M., Blomeyer, D., Buchmann, A. F., Treutlein, J., Schmidt, M. H., Esser, G., Jennen-Steinmetz, C., Rietschel, M., Zimmermann, U. S. & Banaschewski, T. (2011) Catechol-O-methyltransferaseVal 158 Met genotype, parenting practices and adolescent alcohol use: Testing the differential susceptibility hypothesis. Journal of Child Psychology and Psychiatry. Article first published online: 19 APR 2011. Doi: 10.1111/j.1469-7610.2011.02408.x. [Epub ahead of print]Google ScholarPubMed
Laucht, M., Hohm, E., Esser, G., Schmidt, M. H. & Becker, K. (2007) Association between ADHD and smoking in adolescence: Shared genetic, environmental and psychopathological factors. Journal of Neural Transmission 114(8):1097–104.CrossRefGoogle ScholarPubMed
Laucht, M., Treutlein, J., Schmid, B., Blomeyer, D., Becker, K., Buchmann, A. F., Schmidt, M. H., Esser, G., Jennen-Steinmetz, C., Rietschel, M., Zimmermann, U. S. & Banaschewski, T. (2009) Impact of psychosocial adversity on alcohol intake in young adults: Moderation by the LL genotype of the serotonin transporter polymorphism. Biological Psychiatry 66(2):102–109.Google Scholar
Molina, B. S. & Pelham, W. E. (2003) Childhood predictors of adolescent substance use in a longitudinal study of children with ADHD. Journal of Abnormal Psychology 112(3):497–507.Google Scholar
Robinson, T. E. & Berridge, K. C. (2008) Review. The incentive sensitization theory of addiction: Some current issues. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences 363(1507):3137–46.CrossRefGoogle ScholarPubMed
Ryan, S. M., Jorm, A. F., Kelly, C. M., Hart, L. M., Morgan, A. J. & Lubman, D. I. (2011) Parenting strategies for reducing adolescent alcohol use: A Delphi consensus study. BMC. Public Health 11: 13 .CrossRefGoogle ScholarPubMed
Ryan, S. M., Jorm, A. F. & Lubman, D. I. (2010) Parenting factors associated with reduced adolescent alcohol use: A systematic review of longitudinal studies. Australian and New Zealand Journal of Psychiatry 44(9):774–83.Google Scholar
Scribner, R. A., Theall, K. P., Mason, K., Simonsen, N., Schneider, S. K., Towvim, L. G. & Dejong, W. (2011) Alcohol prevention on college campuses: The moderating effect of the alcohol environment on the effectiveness of social norms marketing campaigns. Journal of Studies on Alcohol and Drugs 72(2):232–39.Google Scholar
Spear, L. P. (2002) The adolescent brain and the college drinker: Biological basis of propensity to use and misuse alcohol. Journal of Studies on Alcohol Supplement 14:71–81.Google Scholar
van Leijenhorst, L., Zanolie, K., Van Meel, C. S., Westenberg, P. M., Rombouts, S. A. & Crone, E. A. (2010) What motivates the adolescent? Brain regions mediating reward sensitivity across adolescence. Cerebral Cortex 20(1):61–69.Google Scholar
Wittchen, H. U., Behrendt, S., Hofler, M., Perkonigg, A., Lieb, R., Buhringer, G. & Beesdo, K. (2008) What are the high risk periods for incident substance use and transitions to abuse and dependence? Implications for early intervention and prevention. International Journal of Methods in Psychiatric Research 17(Suppl. 1):S16–S29.Google Scholar