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Genetic Criteria for the Classification of Malformations — A twin study *

Published online by Cambridge University Press:  01 August 2014

L. Gedda ,
G. Del Porto  and
M. T. Lun
L. Gedda*
Affiliation:
The Gregor Mendel Institute of Medical Genetics and Twin Research, Rome
G. Del Porto
Affiliation:
The Gregor Mendel Institute of Medical Genetics and Twin Research, Rome
M. T. Lun
Affiliation:
The Gregor Mendel Institute of Medical Genetics and Twin Research, Rome
*
Istituto di Genetica Medica e Gemellologia Gregorio Mendel, Piazza Galeno 5, 00161 Roma, Italy

Extract

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The authors have investigated the genetic conditioning of malformative phenomena in the series of twin pairs identified by the Italian Institute for Vital Statistics in the five-year period 1961-1965 (approximately, 55000 twin pairs).

For the present study, an original theoretical model has been chosen, that makes the classical twin test of comparison between twin series different as to zygosity be applied to twin series different as to sex composition.

The resulting analysis enables the authors to formulate a hierarchical classification of many of the malformations listed by the Italian Institute for Vital Statistics, according to their degree of genetic conditioning.

Type
Session 12 - Twins and Malformations
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 19 , Issue 1-2 , April 1970 , pp. 212
Copyright
Copyright © The International Society for Twin Studies 1970

Footnotes

*

The full paper is in preparation.

References

* The full paper is in preparation.