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Case 40 - Natural Killer T-Cell Lymphoma

Published online by Cambridge University Press:  19 November 2019

By
Alessandro Franchi
Edited by
Alessandro Franchi
Alessandro Franchi
Affiliation:
Università degli Studi di Firenze, Italy
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Summary

A 35-year-old man presented with nasal obstruction accompanied by repeated episodes of epistaxis and nasal discharge in the last month. In addition, he reported headache and loss of appetite. On physical examination, firm and nontender lymph nodes were found over bilateral levels II, III, and IV. Fiberoptic endoscopic examination of the nasal cavities revealed mucosal ulcers covered by whitish exudate in the left nasal cavity. Laboratory examination revealed mild anemia and leukocytosis. HIV test was negative. Computed tomography showed isoenhancing lesions in the left nasal cavity and paranasal sinuses, associated with bone destruction. Multiple enlarged lymph nodes were observed at bilateral levels IB, II, III, and IV. An incisional biopsy of the nasal mucosa was taken.

Type
Chapter
Information
Pearls and Pitfalls in Head and Neck Pathology , pp. 89 - 90
Publisher: Cambridge University Press
Print publication year: 2019

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References

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Ha, SY, An, J, Park, S. Detection of Epstein–Barr virus-infected lymphoid cells in nasal mucosa or nasopharynx: appearances can be deceptive. Virchows Arch. 2013;462:391–397.CrossRefGoogle ScholarPubMed

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