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Pattern of gastric emptying in the pig: Relation to feeding

Published online by Cambridge University Press:  09 March 2007

P. C. Gregory ,
M. Mcfadyen  and
D. V. Rayner
P. C. Gregory
Affiliation:
Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB2 9SB
M. Mcfadyen
Affiliation:
Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB2 9SB
D. V. Rayner
Affiliation:
Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB2 9SB
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Abstract

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The aims of the present study were to compare the gastric emptying of dry matter (DM) and liquids during the feeding period with that following meal consumption, to clarify the relationship between feeding and gastric emptying, and to investigate how gastric emptying changes in growing animals. The studies were performed in pigs fitted with a gastric cannula and fed on a normal finely ground solid diet mixed with water containing CrEDTA as liquid marker. Gastric emptying was measured using a gastric evacuation technique. It was observed that between 0.75 and 6 h after feeding the total amounts emptied increased, but the proportion of the meal emptied fell, with increase in meal size; emptying of both DM and liquids with large and small meals followed and exponential pattern. In contrast, while the animals were feeding, there was linear and rapid emptying of both DM and liquids following a very short (approximately 2 min) lag phase before emptying began. The rate of emptying increased linearly with body-;weight (by 0.55 g DM/min and by 0.24 ml/min per kg body-weight over the range 58–200 kg) such that the emptying of digestible energy per kg metabolic body-weight (W0.75) was roughly maintained (between 2.9 and 3.2 kJ/min per kg W0.75). This suggests that the rate of emptying may be linked in some way with the metabolic requirements of the body. The biphasic pattern of gastric emptying observed is probably the intrinsic pattern of emptying of a meal which does not require breakdown of particles before emptying can occur.

Keywords

Gastric emptyingGastrointestinal tractPig
Type
Digestion, Absorption and Utilization of Nutrients
Information
British Journal of Nutrition , Volume 64 , Issue 1 , July 1990 , pp. 45 - 58
Copyright
Copyright © The Nutrition Society 1990

References

Ash, R. W. (1962). Gastro-intestinal re-entrant cannulae for studies of digestion in sheep. Animal Production 4, 309–312.Google Scholar
Binnerts, W. T., Van't Klooster, A. T. & Frens, A. M. (1968). Soluble chromium indicator measured by atomic absorption in digestion experiments. Veterinary Record 82, 470.Google Scholar
Brener, W., Hendrix, T. R. & McHugh, P. R. (1983). Regulation of the gastric emptying of glucose. Gastroenterology 85, 76–82.CrossRefGoogle ScholarPubMed
Camilleri, M., Malagelada, J. R., Brown, M. L., Becker, G. & Zinsmeister, A. R. (1985). Relation between antral motility and gastric emptying of solids and liquids in humans. American Journal of Physiology 249, G580–G585.Google ScholarPubMed
Christian, R. R. & Coup, M. R. (1954). Measurement of feed intake by grazing cattle and sheep. VI. The determination of chromic oxide in faeces. New Zealand Journal of Science and Technology 36A, 328–330.Google Scholar
Cuber, J. C. & Laplace, J. P. (1979). Evacuation gastrique de l'amidon et de l'azote d'un régime semi-purifié à base d'amidon de mais chez le Pore. Annales de Zootechnie 28, 173–184.CrossRefGoogle Scholar
Cuber, J. C., Laplace, J. P. & Villiers, P. A. (1980). Fistulation de l'estomac et contenus gastriques résiduals après ingestion d'un régime semi-purifié à bas d'amidon de mais chez le pore. Reproduction, Nutrition, Developpement 20, 1161–1172.CrossRefGoogle Scholar
Elashoff, J. D., Reedy, T. J. & Meyer, J. H. (1982). Analysis of gastric emptying data. Gastroenterology 83, 1306–1312.CrossRefGoogle ScholarPubMed
Gregory, P. C., McFadyen, M. & Rayner, D. V. (1987). The influence of gastrointestinal infusions of glucose on regulation of food intake in pigs. Quarterly Journal of Experimental Physiology 72, 525–535.CrossRefGoogle ScholarPubMed
Gregory, P. C., McFadyen, M. & Rayner, D. V. (1988). Regulation of stomach emptying in pigs. Journal of Physiology 396, 18P.Google Scholar
Gregory, P. C., McFadyen, M. & Rayner, D. V. (1989). Control of gastric emptying in the pig: influence of duodenal infusions of glucose and emulsified fat. Quarterly Journal of Experimental Physiology 74, 109–119.CrossRefGoogle ScholarPubMed
Gregory, P. C., Miller, S. J. & Brewer, A. C. (1985). The relation between food intake and abomasal emptying and small intestinal transit time in sheep. British Journal of Nutrition 53, 373–380.CrossRefGoogle ScholarPubMed
Gregory, P. C. & Rayner, D. V. (1985). Stomach emptying of solids in the pig: relation to feeding. Digestive Diseases and Sciences 30, 771.Google Scholar
Gregory, P. C. & Rayner, D. V. (1986). The role of stomach emptying in short-term control of food intake in pigs. Journal of Physiology 378, 25P.Google Scholar
Gregory, P. C. & Rayner, D. V. (1987). The influence of gastrointestinal infusion of fats on regulation of food intake in pigs. Journal of Physiology 385, 471–481.CrossRefGoogle ScholarPubMed
Hinder, R. A. & Kelly, K. A. (1977). Canine gastric emptying of solids and liquids. American Journal of Physiology 233, E335–E340.Google ScholarPubMed
Horowitz, M., Collins, P. J. & Shearman, D. J. C. (1986). Effect of increasing the caloric/osmotic content of the liquid component of a mixed solid and liquid meal on gastric emptying in obese subjects. Human Nutrition: Clinical Nutrition 40 C, 51–56.Google Scholar
Hunt, J. N. (1980). A possible relation between the regulation of gastric emptying and food intake. American Journal of Physiology 239, G1–G4.Google ScholarPubMed
Hunt, J. N. & Spurrell, N. R. (1951). The pattern of emptying of the human stomach. Journal of Physiology 113, 157–168.CrossRefGoogle ScholarPubMed
Hunt, J. N. & Stubbs, D. F. (1975). The volume and energy content of meals as determinants of gastric emptying. Journal of Physiology 245, 209–225.CrossRefGoogle ScholarPubMed
Johansson, C. & Eklund, K. (1976). Relation between body weight and gastric and intestinal handling of an oral caloric load. Gut 17, 456–462.CrossRefGoogle ScholarPubMed
Kalogeris, T. J., Reidelberger, R. D. & Mendel, V. E. (1983). Effect of nutrient density and composition of liquid meals on gastric emptying in feeding rats. American Journal of Physiology 244, R865–R871.Google ScholarPubMed
Kleiber, M. (1947). Bodysize and metabolic rate. Physiology Reviews 27, 511–541.CrossRefGoogle Scholar
Laplace, J. P., Pons, O., Cuber, J. C., Kabore, C. & Villiers, P. A. (1981). Effects de la nature de l'amidon (blé ou mais) et des proteines (poisson ou gluten) sur les facteurs de contrôle et le décours de l'évacuation gastrique d'un régime semi-purifié chez le porc. Applications de l'analyse multidimensionelle et de la régression polynomiale. Annales de Zootechnie 30, 209–248.CrossRefGoogle Scholar
Laplace, J. P. & Tomassone, R. (1970). Evacuation gastro-duodénale chez le pore. Annales de Zootechnie 19, 303–332.CrossRefGoogle Scholar
Lavigne, M. E., Wiley, Z. D., Meyer, J. H., Martin, P. & MacGregor, I. L. (1978). Gastric emptying rates of solid foods in relation to body size. Gastroenterology 74, 1258–1260.CrossRefGoogle ScholarPubMed
Low, A. G., Pittman, R. J. & Elliott, R. J. (1985). Gastric emptying of barley-soya-bean diets in the pig: effects of feeding level, supplementary maize oil, sucrose or cellulose and water intake. British Journal of Nutrition 54, 437–447.CrossRefGoogle ScholarPubMed
McCann, M. J. & Stricker, E. M. (1986). Gastric emptying of glucose loads in rats: effects of insulin-induced hypoglycemia. American Journal of Physiology 251, R609–R613.Google ScholarPubMed
McHugh, P. R. & Moran, T. H. (1979). Calories and gastric emptying: A regulatory capacity with implications for feeding. American Journal of Physiology 236, R254–R260.Google ScholarPubMed
McHugh, P. R., Moran, T. H. & Barton, G. N. (1975). Satiety: A graded behavioral phenomenon regulating calorie intake. Science 190, 167–169.CrossRefGoogle Scholar
McHugh, P. R., Moran, T. H. & Wirth, J. B. (1982). Postpyloric regulation of gastric emptying in rhesus monkeys. American Journal of Physiology 243, R408–R415.Google ScholarPubMed
Malagelada, J. R., Go, V. L. W. & Summerskill, W. H. J. (1979). Different gastric, pancreatic and biliary responses to solid-liquid or homogenized meals. Digestive Diseases and Sciences 24, 101–109.CrossRefGoogle ScholarPubMed
Meyer, J. H., Dressman, J., Fink., A. & Amidon, G. (1985). Effect of size and density on canine gastric emptying of nondigestible solids. Gastroenterology 89, 805–813.CrossRefGoogle ScholarPubMed
Meyer, J. H., Ohashi, H., Jehn, D. & Thomson, J. B. (1981). Size of liver particles emptied from the human stomach. Gastroenterology 80, 489–496.CrossRefGoogle ScholarPubMed
Meyer, J. H., Thomson, J. B., Cohen, M. B., Shadchehr, A. & Mandiola, S. A. (1979). Sieving of solid food by the canine stomach and sieving after gastric surgery. Gastroenterology 76, 804–813.CrossRefGoogle ScholarPubMed
Moore, J. G., Christian, P. E., Brown, J. A., Brophy, C., Datz, F., Taylor, A. & Alazraki, N. (1984). Influence of meal weight and caloric content on gastric emptying of meals in man. Digestive Diseases and Sciences 29, 513–519.CrossRefGoogle ScholarPubMed
Rayner, D. V. & Gregory, P. C. (1989). The role of the gastrointestinal tract in the control of voluntary food intake. In The Voluntary Food Intake of Pigs. Occasional Publication no. 13, British Society of Animal Production, pp. 27–39 [Forbes, J. M., Varley, M. A. and Lawrence, T. L. J., editors]. Milton Keynes: British Society of Animal Production.Google Scholar
Reed, J. H. & Kidder, D. E. (1972). The effect of glucose, galactose and sorbitol on gastric emptying in the young pig. Quarterly Journal of Experimental Physiology 57, 30–36.CrossRefGoogle ScholarPubMed
Rosenthal, S. & Nasset, E. S. (1958). Gastric emptying and intestinal absorption of carbohydrate and protein as influenced by the nature of the meal. Journal of Nutrition 66, 91–103.CrossRefGoogle ScholarPubMed
Setler, P. E. & Smith, G. P. (1969). Gastric emptying in rats with chronic gastric fistulas. American Journal of Digestive Diseases 14, 137–142.CrossRefGoogle ScholarPubMed
Tan, T. N., Weston, R. H. & Hogan, J. P. (1971). Use of 103Ru-labelled tris (1,10-phenanth ruthenium(11)) chloride as a marker in digestion studies in sheep. International Journal of Applied Radiation and Isotopes 22, 301–308.CrossRefGoogle Scholar
Uden, P., Colucci, P. E. & Van Soest, P. (1980). Investigation of chromium, cerium and cobalt, as markers in digesta – rate of passage studies. Journal of Science of Food and Agriculture 31, 625–632.CrossRefGoogle ScholarPubMed
Wright, R. A., Krinsky, S., Fleeman, C., Trujillo, J. & Teague, E. (1983). Gastric emptying and obesity. Gastroenterology 84, 747–751.CrossRefGoogle ScholarPubMed