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High-quality photoacoustic imaging by usingof concentration-adjustable glycerin as an acoustic couplant

Published online by Cambridge University Press:  22 November 2006

Sihua Yang  and
Huaimin Gu
Sihua Yang
Affiliation:
MOE Key Laboratory of Laser Life Science & Institute of Laser Life Science, South China Normal University, Guangzhou 510631, P.R. China
Huaimin Gu*
Affiliation:
MOE Key Laboratory of Laser Life Science & Institute of Laser Life Science, South China Normal University, Guangzhou 510631, P.R. China
*
guhm@scnu.edu.cn
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Abstract

The influences of mismatch of ultrasonic propagation velocities on photoacoustic imaging are studied. The concentration-adjustable glycerin is used as an ultrasonic couplant to match the ultrasonic velocities in different media in order to eliminate the acoustic refraction, reduce the acoustic reflection, and rectify the acoustic path difference. Two biological phantoms are tested by using water and glycerin as ultrasonic couplant, respectively. The spatial resolution of reconstructed image by experimental evaluation also is estimated to be 0.12 mm. The experimental results demonstrate that the high-quality photoacoustic imaging can be obtained by matching the ultrasonic propagation velocities in different media. The contrast of reconstructed image is significantly improved and the image artifacts are obviously reduced after matching ultrasonic velocity. It has potential to promote photoacoustic imaging as a clinical diagnosis technique.

Keywords

Type
Research Article
Information
The European Physical Journal - Applied Physics , Volume 37 , Issue 1 , January 2007 , pp. 87 - 92
Copyright
© EDP Sciences, 2006

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References

Su, Y., Zhang, F., Xu, K., Yao, J., Wang, R.K., J. Phys. D Appl. Phys. 38, 15 (2005)
Yaguang Zeng, Da Xing, Yi Wang, Bangzhen Yin, Qun Chen, Opt. Lett. 29, 15 (2004)
Wang, X., Pang, Y., Ku, G., Xie, X., Stoica, G., Wang, L.-H., Nat. Biotechnol. 21, 7 (2003)
Siphanto, R.I., Thumma, K.K., Kolkman, R.G.M., van Leeuwen, T.G., de Mul, F.F.M., van Neck, J.W., van Adrichem, L.N.A., Steenbergen, W., Opt. Express 13, 1 (2005) CrossRef
Yuan Xu, Li Long, V. Wang, IEEE T. Ultrason. Ferr. 50, 9 (2003) CrossRef
Bangzheng Yin, Da Xing, Yi Wang, Yaguang Zeng, Yi Yan, Qun Chen, Med. Biol. 49, 7 (2004)
Diwu Yang, Da Xing, Huaimin Gu, Yi Tan, Lvming Zeng, Appl. Phys. Lett. 87, 19 (2005)
Diwu Yang, Da Xing, Yi Tan, Huaimin Gu, Sihua Yang, Appl. Phys. Lett. 88, 17 (2006)
Yi Tan, Da Xing, Yi Wang, Zeng Yangguang, Yin Bangzheng, Acta Optica Sinica 25, 1 (2005)
Yaguang Zeng, Da Xing, Hongbo Fu, Yin Bangzheng, Chin. J. Lasers 32, 1 (2005)
Robert, A., Kruger, Pingyu Liu, Yuncai Fang, C.R. Appledon, Med. Phys. 22, 10 (1995)
Kostli, K.P., Beard, P.C., Appl. Opt. 42, 10 (2003) CrossRef
Hoelen, C.G.A., de Mul, F.F.M., Appl. Opt. 39, 31 (2000) CrossRef
Minghua, Xu, Yuan, Xu, Lihong, V. Wang, IEEE T. Bio-Med. Eng. 50, 9 (2003) CrossRef
Yi Wang, Da Xing, Yaguang Zeng, Qun Chen, Phys. Med. Biol. 49, 14 (2004)
P.M. Morse, K.U. Ingard, Theoretical acoustics (McGraw-Hill, New York, 1954)
Minghua, Xu, Lihong, V. Wang, IEEE T. Med. Imaging 21, 7 (2002) CrossRef