Hostname: page-component-78c5997874-m6dg7 Total loading time: 0 Render date: 2024-11-09T00:30:21.875Z Has data issue: false hasContentIssue false

Derealization Syndrome and the Outcome of Schizophrenia: A Report from the International Pilot Study of Schizophrenia

Published online by Cambridge University Press:  29 January 2018

Hai-Gwo Hwu*
Affiliation:
Department of Mental Health, Taipei City Psychiatric Center, 54, Lane 151, Sec. 5, Shin- Yi Road, Taipei, Taiwan, 105, R.O.C.; National Taiwan University College of Medicine, Taipei, Taiwan, R.O.C.
Chu-Chang Chen
Affiliation:
National Taiwan University College of Medicine, and National Taiwan University Hospital, Taipei, Taiwan, R.O.C.
Ming Tso Tsuang
Affiliation:
University of Iowa College of Medicine, U.S.A.
Wen-Shing Tseng
Affiliation:
Department of Psychiatry, University of Hawaii College of Medicine, U.S.A.
*
Correspondence.

Summary

Eighty-five schizophrenic patients were found to have worse two-year follow-up outcome (history of remission, clinical course, improvement in psychotic symptoms, general treatment result) than 39 non-schizophrenic psychotic patients. The outcome of 36 schizophrenic patients with derealization at initial evaluation, especially when nine hebephrenics were excluded, was better than that of 49 schizophrenic patients without derealization but similar to that of 39 non-schizophrenic patients. The hebephrenics with derealization demonstrated similar outcomes to schizophrenic patients without derealization. In non-schizophrenic patients, derealization had no prognostic significance.

Type
Research Article
Copyright
Copyright © Royal College of Psychiatrists, 1981 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Bland, R. C. & Orn, H. (1980) Prediction of long-term outcome from presenting symptoms in schizophrenia. Journal of Clinical Psychiatry, 41, 85–8.Google ScholarPubMed
Brauer, R., Harrow, M. & Tucker, G. J. (1970) Depersonalization phenomena in psychiatric patients. British Journal of Psychiatry, 117, 509–15.CrossRefGoogle ScholarPubMed
Bromet, E., Harrow, M. & Kasl, S. (1974) Premorbid functioning and outcome in schizophrenics and non-schizophrenics. Archives of General Psychiatry, 30, 203–7.CrossRefGoogle Scholar
Carpenter, W. T. Jr., Bartko, J. J., Strauss, J. S. & Hawk, A. B. (1978) Signs and symptoms as predictors of outcome: a report from the international pilot study of schizophrenia. American Journal of Psychiatry, 135, 940–5.Google ScholarPubMed
Chapman, J. (1966) The early symptoms of schizophrenia. British Journal of Psychiatry, 112, 225–51.CrossRefGoogle ScholarPubMed
Chen, C. C., Tsuang, M. T. & Tseng, W. S. (1975) A two-year follow-up study of 85 schizophrenics. Medical Journal of Malaysia, 30, Supp. No. 1, 8892.Google Scholar
Choi, S. C. (1978) Introductory Applied Statistics in Science. New Jersey: Prentice-Hall.Google Scholar
Eitinger, L., Laane, C. L. & Langfeldt, G. (1958) The prognostic value of the clinical picture and the therapeutic value of physical treatment in schizophrenia and the schizophreniform states. Acta Psychiatrica et Neurologica Scandinavica, 33, 3353.CrossRefGoogle Scholar
Harrow, M., Grinker, R. R. Sr. & Silverstein, M. L. (1978) Is modern-day schizophrenic outcome still negative? American Journal of Psychiatry, 135, 1156–62.Google ScholarPubMed
Hawk, A. B. & Carpenter, W. T. Jr. (1975) Diagnostic criteria and five-year outcome in schizophrenia. Archives of General Psychiatry, 32, 343–7.CrossRefGoogle ScholarPubMed
Holmboe, R. & Astrup, C. (1957) A follow-up study of 255 patients with acute schizophrenia and schizophreniform psychoses. Acta Psychiatrica et Neurologica Scandinavica, Suppl. 115.Google Scholar
Huber, G., Gross, G. & Schüttler, R. (1975) A long-term follow-up study of schizophrenia: psychiatric course of illness and prognosis. Acta Psychiatrica Scandinavica, 52, 4957.Google Scholar
Langfeldt, G. (1960) Diagnosis and prognosis of schizophrenia. Proceedings of the Royal Society of Medicine, 53, 1047–52.Google ScholarPubMed
Langfeldt, G. (1969) Schizophrenia: diagnosis and prognosis. Behavioral Science, 14, 173–82.CrossRefGoogle ScholarPubMed
McCabe, M. S., Fowler, R. C., Cadoret, R. J. & Winokur, G. (1972) Symptom differences in schizophrenia with good and poor prognosis. American Journal of Psychiatry, 128, 1239–43.CrossRefGoogle ScholarPubMed
Raman, A. C. & Murphy, H. B. M. (1972) Failure of traditional prognostic indicators in Afro-Asian Psychotics: results of a long-term follow-up survey. Journal of Nervous and Mental Disease, 154, 238–47.CrossRefGoogle Scholar
Simon, W. & Wirt, A. L. (1961) Prognostic factors in schizophrenia. American Journal of Psychiatry, 117, 887–90.CrossRefGoogle Scholar
Simon, W., Wirt, A. L. Wirt, R. D. & Halloran, A. V. (1965) Long-term follow-up study of schizophrenic patients. Archives of General Psychiatry, 12, 510–15.CrossRefGoogle ScholarPubMed
Stephens, J. H. & Astrup, C. (1963) Prognosis in process and non-process schizophrenia. American Journal of Psychiatry, 119, 945–52.CrossRefGoogle Scholar
Stephens, J. H., Astrup, C. & Mangrum, J. C. (1966) Prognostic factors in recovered and deteriorated schizophrenics. American Journal of Psychiatry, 122, 1116–21.CrossRefGoogle ScholarPubMed
Stephens, J. H., Astrup, C. & Mangrum, J. C. (1967) Prognosis in schizophrenia. Archives of General Psychiatry, 16, 693–8.CrossRefGoogle ScholarPubMed
Strauss, J. S. & Carpenter, W. T. Jr. (1972) The prediction of outcome in schizophrenia. I. Characteristics of outcome. Archives of General Psychiatry, 27, 739–46.Google Scholar
Strauss, J. S. & Carpenter, W. T. Jr. (1974a) Characteristic symptoms and outcome in schizophrenia. Archives of General Psychiatry, 30, 429–34.CrossRefGoogle ScholarPubMed
Strauss, J. S. & Carpenter, W. T. Jr. (1974b) The prediction of outcome in schizophrenia. II. Relationships between predictor and outcome variables. Archives of General Psychiatry, 31, 3742.Google Scholar
Tan, K. L. & Chen, C. C. (1979) A preliminary report on the seven-year follow-up of 86 schizophrenics. Bulletin, Chinese Society of Neurology and Psychiatry (R.O.C.), 5 (1), 1516.Google Scholar
Tsuang, M. T., Woolson, R. F. & Fleming, J. A. (1979) Long-term outcome of major psychoses. I. Schizophrenia and affective disorders compared with psychiatrically symptom-free surgical conditions. Archives of General Psychiatry, 36, 1295–301.Google ScholarPubMed
Vaillant, G. E. (1962a) The prediction of recovery in schizophrenia. Journal of Nervous and Mental Disease, 135, 534–43.CrossRefGoogle ScholarPubMed
Vaillant, G. E. (1962b) Prospective prediction of schizophrenic remission. Archives of General Psychiatry, 11, 509–18.Google Scholar
Vaillant, G. E. (1964) An historical review of the remitting schizophrenics. Journal of Nervous and Mental Disease, 138, 4856.CrossRefGoogle Scholar
Varsamis, J. & Adamson, J. D. (1971) Early schizophrenia. Canadian Psychiatric Association Journal, 6, 487–97.Google Scholar
Welner, J. & Strömgren, E. (1958) Clinical and genetic studies on benign schizophreniform psychoses based on a follow-up. Acta Psychiatrica et Neurologica Scandinavica, 33, 337–99.CrossRefGoogle ScholarPubMed
World Health Organization (1973) The International Pilot Study of Schizophrenia, Vol. 1. Geneva: WHO.Google Scholar
World Health Organization (1979) Schizophrenia: An International Follow-up Study. Chichester: John Wiley.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.