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Utilising genetic contributions to maximise long term response to selection

Published online by Cambridge University Press:  05 November 2021

B Grundy
Affiliation:
Scottish Agricultural College, West Mains Road, Edinburgh EH9 3JG, United Kingdom
B Villanueva
Affiliation:
Scottish Agricultural College, West Mains Road, Edinburgh EH9 3JG, United Kingdom
J A Woolliams
Affiliation:
Roslin Institute (Edinburgh), Roslin, Midlothian EH25 9PS, United Kingdom
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Extract

The concept of long term contributions was devised by Wray and Thompson (1990) to describe the accumulation of inbreeding in a population under selection, and further developed by Woolliams and Thompson (1994) to describe genetic progress. This study describes a method to utilise these relationships for optimising schemes where the breeding objective is cumulative net response with restrictions on inbreeding. The selection decisions at a given generation can be obtained from maximising the function f(x) of accumulated gain corrected for squared contributions: f(x) = xTg-λTAx, where x is the vector of long term contributions, g is the vector of estimated breeding values, A is the matrix of genetic relationships which has not been corrected for reduced Mendelian variance with inbreeding (unlike the method of Wray and Goddard, 1994), and λ is a constant taking positive values.

Type
Animal Breeding
Copyright
Copyright © The British Society of Animal Science 1996

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References

Woolliams, J.A. and Thompson, R. 1994. A theory of genetic contributions. Proceedings of the 5th World Congress on Genetics Applied to Livestock Production 19: 127134 Google Scholar
Wray, N.R and Thompson, R 1990. Prediction of rates of inbreeding in selected populations. Genetical Research 55: 4154 10.1017/S0016672300025180CrossRefGoogle ScholarPubMed
Wray, N.R. and Goddard, M.E. 1994. Increasing long-term response to selection. Genetics Selection Evolution 26: 431451 10.1186/1297-9686-26-5-431CrossRefGoogle Scholar