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Photoembossing for Surface Texturing of Films and Fibres for Biomedical Applications

Published online by Cambridge University Press:  03 February 2012

Nanayaa Freda Hughes-Brittain
Affiliation:
School of Engineering and Material Science. Centre for Material Research, Queen Mary University of London, London, United Kingdom
Olivier T. Picot
Affiliation:
School of Engineering and Material Science. Centre for Material Research, Queen Mary University of London, London, United Kingdom
Lin Qiu
Affiliation:
School of Engineering and Material Science. Centre for Material Research, Queen Mary University of London, London, United Kingdom
Carlos Sanchez
Affiliation:
Departmento de Fisica de la Materia Condensada. Faculta de Ciencias, Universidad de Zaragoza, Zaragoza, Spain
Ton Peijs
Affiliation:
School of Engineering and Material Science. Centre for Material Research, Queen Mary University of London, London, United Kingdom Faculty of Chemistry and Chemical Engineering, Eindhoven University, Eindhoven, Netherlands.
Kees Bastiaansen
Affiliation:
School of Engineering and Material Science. Centre for Material Research, Queen Mary University of London, London, United Kingdom Faculty of Chemistry and Chemical Engineering, Eindhoven University, Eindhoven, Netherlands.
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Abstract

Photoembossing is a technique used to create relief structures using a patterned contact photo-mask exposure and a thermal development step. Typically, the photopolymer consists of a polymer binder and a monomer in a 1/1 ratio together with a photo-initiator which results in a solid and non-tacky material at room temperature. Here, new mixtures for photoembossing are presented which are potentially biocompatible. A polymer binder such as poly (methyl methacrylate) with triacrylate monomer and biocompatible photo-initiator Irgacure 369 is used. Photopolymer films produced are successfully embossed with height of relief structures controlled by UV dosage and developing temperature. Furthermore, the photopolymer blend is electrospun to form fibres with diameters of 5 μm which are then photoembossed. The photoembossed fibres showed homogenous reproducible surface textures. Biocompatibility is evaluated by culturing human umbilical vein endothelial cells (HUVECs) on films of this photopolymer blend. The study shows that photoembossing is a feasible method of producing surface texturing on both films and electrospun fibres for tissue engineering applications.

Type
Research Article
Copyright
Copyright © Materials Research Society 2012

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References

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