Hostname: page-component-78c5997874-8bhkd Total loading time: 0 Render date: 2024-11-18T05:50:31.625Z Has data issue: false hasContentIssue false

Biomedical application of ferrofluids containing magnetite nanoparticles

Published online by Cambridge University Press:  21 March 2011

D. K. Kim
Affiliation:
Materials Chemistry Division, Royal Institute of Technology, SE-100 44 Stockholm, Sweden
W. Voit
Affiliation:
Engineering Materials Physics Division, Royal Institute of Technology, SE-100 44 Stockholm, Sweden XaarJet AB, SE-175 26 Järfälla, Sweden
W. Zapka
Affiliation:
XaarJet AB, SE-175 26 Järfälla, Sweden
B. Bjelke
Affiliation:
MR Research Center, Dept. of Clinical Neuroscience, Karolinska Institutet, SE-171 76 Stockholm, Sweden
M. Muhammed
Affiliation:
Materials Chemistry Division, Royal Institute of Technology, SE-100 44 Stockholm, Sweden
K.V. Rao
Affiliation:
Engineering Materials Physics Division, Royal Institute of Technology, SE-100 44 Stockholm, Sweden
Get access

Abstract

Ferrofluids containing superparamagnetic Fe3O4 nanoparticles have been prepared by a controlled co-precipitation method.The aggregation of the particles was prevented by using a polymeric starch network as a coating agent. Structural and magnetic measurements reveal a particle size of around 6 nm, with a clear evidence of a uniform particle coating. The ferrofluids have been used as a contrast agent for MR imaging in biological tissue.

Type
Research Article
Copyright
Copyright © Materials Research Society 2001

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

1. Remsen, L. G., McCormick, C. I., Roman-Goldstein, S., Nilaver, G., Weissleder, R., Bogdanov, A., Hellstrom, I., Kroll, R. A. and Neuwelt, E. A., American Journal of Neuroradiology 17, 411 (1996)Google Scholar
2. Schaffer, B. K., Linker, C., Papisov, M., Tsai, E., Nossiff, N., Shibata, T., Bogdanov, A. Jr., Brady, T. J. and Weissleder, R., Magnetic Resonance Imaging 11, 411 (1993)Google Scholar
3. Bogdanov, A. and Weissleder, R., Trends Biotechnol. 16, 5 (1998)Google Scholar
4. Moore, A., Basilion, J. P., Chiocca, E. A. and Weissleder, R., Biochim. Biophys. Acta. 1402, 239 (1998)Google Scholar
5. Massart, R., IEEE Trans. Magn. MAG-17, 1247 (1981)Google Scholar
6. Kim, D. K., Zhang, Y., Kehr, J., Klason, T., Bjelke, B., and Muhammed, M., J. Magn. Magn. Mater 225, 256 (2001)Google Scholar
7. Doviáš, B., Qiu, X. and Rybinsky, W. V., Surfactant Science Series Vol. 81. MARCEL DEKKER, INC.Google Scholar
8. Chantrell, R. W., Popplewell, J. and Charles, S. W., IEEE Trans. Magn. MAG-14, 975 (1978)Google Scholar
9. Bradbury, A., Menear, S., O'Grady, K. and Chantrell, R. W., IEEE Trans. Magn. MAG-20, 1846 (1984)Google Scholar
10. Néel, L., Ann. Geophys. 5, 99 (1949)Google Scholar