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Selective Screening of Hospitalized Patients for the Presence of Asymptomatic Hepatitis B Virus Carriage: Predictability Based on Census Tract Data

Published online by Cambridge University Press:  02 January 2015

Larry M. Baddour ,
Billy R. Jennings ,
Pamela T. Osborne ,
Robert C. Rendtorff ,
Marge C. Moffatt ,
Ginger M. Luther  and
Jamie L. Holcomb
Larry M. Baddour*
Affiliation:
Departments of Medicine and Pathology, University of Tennessee, Memphis; Regional Medical Center; and the Memphis and Shelby County Health Department, Memphis, Tennesse
Billy R. Jennings
Affiliation:
Departments of Medicine and Pathology, University of Tennessee, Memphis; Regional Medical Center; and the Memphis and Shelby County Health Department, Memphis, Tennesse
Pamela T. Osborne
Affiliation:
Departments of Medicine and Pathology, University of Tennessee, Memphis; Regional Medical Center; and the Memphis and Shelby County Health Department, Memphis, Tennesse
Robert C. Rendtorff
Affiliation:
Departments of Medicine and Pathology, University of Tennessee, Memphis; Regional Medical Center; and the Memphis and Shelby County Health Department, Memphis, Tennesse
Marge C. Moffatt
Affiliation:
Departments of Medicine and Pathology, University of Tennessee, Memphis; Regional Medical Center; and the Memphis and Shelby County Health Department, Memphis, Tennesse
Ginger M. Luther
Affiliation:
Departments of Medicine and Pathology, University of Tennessee, Memphis; Regional Medical Center; and the Memphis and Shelby County Health Department, Memphis, Tennesse
Jamie L. Holcomb
Affiliation:
Departments of Medicine and Pathology, University of Tennessee, Memphis; Regional Medical Center; and the Memphis and Shelby County Health Department, Memphis, Tennesse
*
University of Tennessee, Division of Infectious Diseases, 956 Court Avenue, Room H-308, Memphis, TN 38163
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Abstract

Review of all hepatitis B surface antigen-positive patients reported to the county health department over the past 3 years showed that 60% of patients had been diagnosed at our hospital, which serves an inner city, predominantly black, indigent population. Sera from 524 adult patients admitted to the hospital were prospectively collected and tested for hepatitis B surface antigen, eight (1.5%) of which were antigen-positive. Census tract data allowed us to perform selective screening of sera from 95 other patients who were subsequently hospitalized and deemed “high risk” for hepatitis B infection. Nine of 95 (9.5%) selectively screened samples were positive for hepatitis B surface antigen, which represented a significantly higher rate of antigen carriage (P<0.0001) in hospitalized patients from “high risk” areas than that found in the general population screen. The methodology presented herein may be useful in providing a means of identifying hepatitis B surface antigen-positive patients from adult, urban, indigent care populations.

Type
Original Articles
Information
Infection Control & Hospital Epidemiology , Volume 7 , Issue 11 , November 1986 , pp. 546 - 549
Copyright
Copyright © The Society for Healthcare Epidemiology of America 1986

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