Book contents
- High-Risk Pregnancy: Management Options
- High-Risk Pregnancy: Management Options
- Copyright page
- Contents
- Contributors
- Section 1 Prepregnancy Problems
- Section 2 Early Prenatal Problems
- Section 3 Late Prenatal – Fetal Problems
- Section 4 Problems Associated with Infection
- Chapter 24 Hepatitis Virus Infections in Pregnancy (Content last reviewed: 23rd July 2019)
- Chapter 25 Human Immunodeficiency Virus in Pregnancy (Content last reviewed: 23rd July 2019)
- Chapter 26 Rubella, Measles, Mumps, Varicella, and Parvovirus in Pregnancy (Content last reviewed: 11th November 2020)
- Chapter 27 Cytomegalovirus, Herpes Simplex Virus, Adenovirus, Coxsackievirus, and Human Papillomavirus in Pregnancy (Content last reviewed: 11th November 2020)
- Chapter 28 Parasitic Infections in Pregnancy (Content last reviewed: 15th June 2018)
- Chapter 29 Other Infectious Conditions in Pregnancy (Content last reviewed: 11th November 2020)
- Section 5 Late Pregnancy – Maternal Problems
- Chapter 30 Substance Misuse in Pregnancy (Content last reviewed: 15th June 2018)
- Chapter 31 Medication in Pregnancy (Content last reviewed: 11th November 2020)
- Chapter 32 Hypertension in Pregnancy (Content last reviewed: 11th November 2020)
- Chapter 33 Cardiac Disease in Pregnancy (Content last reviewed: 11th November 2020)
- Chapter 34 Respiratory Disease in Pregnancy (Content last reviewed: 15th June 2018)
- Chapter 35 Anemia and White Blood Cell Disorders in Pregnancy
- Chapter 36 Hematological Malignancies in Pregnancy (Content last reviewed: 14th December 2020)
- Chapter 37 Thrombocytopenia and Bleeding Disorders in Pregnancy (Content last reviewed: 11th November 2020)
- Chapter 38 Disorders of Coagulation in Pregnancy (Content last reviewed: 11th November 2020)
- Chapter 39 Autoimmune Disease in Pregnancy (Content last reviewed: 23rd July 2019)
- Chapter 40 Diabetes in Pregnancy (Content last reviewed: 11th November 2020)
- Chapter 41 Thyroid Disease in Pregnancy (Content last reviewed: 14th December 2020)
- Chapter 42 Pituitary and Adrenal Disease in Pregnancy (Content last reviewed: 14th December 2020)
- Chapter 43 Gastrointestinal and Liver Diseases in Pregnancy (Content last reviewed: 14th December 2020)
- Chapter 44 Neurologic Complications in Pregnancy (Content last reviewed: 15th October 2018)
- Chapter 45 Renal Disorders in Pregnancy (Content last reviewed: 15th October 2018)
- Chapter 46 Spine and Joint Disorders in Pregnancy (Content last reviewed: 23rd July 2019)
- Chapter 47 Skin Disease in Pregnancy (Content last reviewed: 23rd July 2019)
- Chapter 48 Malignant Disease in Pregnancy (Content last reviewed: 15th October 2018)
- Chapter 49 Pregnancy After Transplantation (Content last reviewed: 14th December 2020)
- Chapter 50 Trauma in Pregnancy
- Chapter 51 Mental Health Disorders in Pregnancy (Content last reviewed: 14th December 2020)
- Section 6 Late Prenatal – Obstetric Problems
- Section 7 Postnatal Problems
- Section 8 Normal Values
- Index
- References
Chapter 31 - Medication in Pregnancy (Content last reviewed: 11th November 2020)
from Section 5 - Late Pregnancy – Maternal Problems
Published online by Cambridge University Press: 15 November 2017
- High-Risk Pregnancy: Management Options
- High-Risk Pregnancy: Management Options
- Copyright page
- Contents
- Contributors
- Section 1 Prepregnancy Problems
- Section 2 Early Prenatal Problems
- Section 3 Late Prenatal – Fetal Problems
- Section 4 Problems Associated with Infection
- Chapter 24 Hepatitis Virus Infections in Pregnancy (Content last reviewed: 23rd July 2019)
- Chapter 25 Human Immunodeficiency Virus in Pregnancy (Content last reviewed: 23rd July 2019)
- Chapter 26 Rubella, Measles, Mumps, Varicella, and Parvovirus in Pregnancy (Content last reviewed: 11th November 2020)
- Chapter 27 Cytomegalovirus, Herpes Simplex Virus, Adenovirus, Coxsackievirus, and Human Papillomavirus in Pregnancy (Content last reviewed: 11th November 2020)
- Chapter 28 Parasitic Infections in Pregnancy (Content last reviewed: 15th June 2018)
- Chapter 29 Other Infectious Conditions in Pregnancy (Content last reviewed: 11th November 2020)
- Section 5 Late Pregnancy – Maternal Problems
- Chapter 30 Substance Misuse in Pregnancy (Content last reviewed: 15th June 2018)
- Chapter 31 Medication in Pregnancy (Content last reviewed: 11th November 2020)
- Chapter 32 Hypertension in Pregnancy (Content last reviewed: 11th November 2020)
- Chapter 33 Cardiac Disease in Pregnancy (Content last reviewed: 11th November 2020)
- Chapter 34 Respiratory Disease in Pregnancy (Content last reviewed: 15th June 2018)
- Chapter 35 Anemia and White Blood Cell Disorders in Pregnancy
- Chapter 36 Hematological Malignancies in Pregnancy (Content last reviewed: 14th December 2020)
- Chapter 37 Thrombocytopenia and Bleeding Disorders in Pregnancy (Content last reviewed: 11th November 2020)
- Chapter 38 Disorders of Coagulation in Pregnancy (Content last reviewed: 11th November 2020)
- Chapter 39 Autoimmune Disease in Pregnancy (Content last reviewed: 23rd July 2019)
- Chapter 40 Diabetes in Pregnancy (Content last reviewed: 11th November 2020)
- Chapter 41 Thyroid Disease in Pregnancy (Content last reviewed: 14th December 2020)
- Chapter 42 Pituitary and Adrenal Disease in Pregnancy (Content last reviewed: 14th December 2020)
- Chapter 43 Gastrointestinal and Liver Diseases in Pregnancy (Content last reviewed: 14th December 2020)
- Chapter 44 Neurologic Complications in Pregnancy (Content last reviewed: 15th October 2018)
- Chapter 45 Renal Disorders in Pregnancy (Content last reviewed: 15th October 2018)
- Chapter 46 Spine and Joint Disorders in Pregnancy (Content last reviewed: 23rd July 2019)
- Chapter 47 Skin Disease in Pregnancy (Content last reviewed: 23rd July 2019)
- Chapter 48 Malignant Disease in Pregnancy (Content last reviewed: 15th October 2018)
- Chapter 49 Pregnancy After Transplantation (Content last reviewed: 14th December 2020)
- Chapter 50 Trauma in Pregnancy
- Chapter 51 Mental Health Disorders in Pregnancy (Content last reviewed: 14th December 2020)
- Section 6 Late Prenatal – Obstetric Problems
- Section 7 Postnatal Problems
- Section 8 Normal Values
- Index
- References
Summary
Drug use during pregnancy and lactation remain underdeveloped areas of clinical pharmacology and drug research. Pregnancy risk factors together with an increased incidence of chronic diseases and a rise in the average maternal age predict medication use will continue to rise during gestation. Common exposure categories include over-the-counter (OTC) medication, psychiatric agents, gastrointestinal medications, herbals, vitamins, antibiotics, and topical products. Only a few medications have been tested specifically for safety and efficacy during human gestation. Profound physiologic changes occur during both normal and pathologic pregnancy that may dramatically alter drug clearance, efficacy, and safety. Under such circumstances, the danger of a drug to mothers, their fetuses, and nursing infants cannot be determined with any confidence until it has been widely used. It is important that women with medical disorders such as diabetes, hypertension, epilepsy, and inflammatory bowel disease continue necessary therapy while pregnant. Unfortunately, many physicians stop or delay medically important agents precisely because of the lack of information.
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- High-Risk PregnancyManagement Options, pp. 807 - 845Publisher: Cambridge University PressFirst published in: 2017