In this prospective, longitudinal study, we examined the risk factors for severe acute respiratory coronavirus virus 2 (SARS-CoV-2) infection among a cohort of chronic hemodialysis (HD) patients and healthcare personnel (HCPs) over a 6-month period. The risk of SARS-CoV-2 infection among HD patients and HCPs was consistently associated with a household member having SARS-CoV-2 infection.

Gastropods are an important component of subtidal Antarctic communities including in common association with macroalgae. Nonetheless, limited data exist detailing their abundance and distribution on macroalgal species. This study documents the abundance and species composition of gastropod assemblages on the two largest, blade-forming Antarctic macroalgae, Himantothallus grandifolius and Sarcopeltis antarctica, sampled across two depths (9 and 18 m) at four sites for each species off Anvers Island, Antarctica. Gastropods were also enumerated on Desmarestia anceps, Desmarestia antarctica and Plocamium sp. but were not included in the main analyses because of small sample sizes. There were major differences between the gastropod assemblages on deep vs shallow H. grandifolius and S. antarctica with much higher numbers of individuals and also greater numbers of gastropod species at the greater depth. Differences between the gastropod assemblages on H. grandifolius and S. antarctica across sampling sites were apparent in non-parametric, multivariate analyses, although depth contributed more than site to these differences. Within common sites, assemblages on H. grandifolius were significantly different from those on S. antarctica at 18 m depth but not at 9 m depth, indicating that the host species can be but is not always more important than site in influencing the gastropod assemblages.

Praziquantel (PZQ) remains the only drug of choice for the treatment of schistosomiasis, caused by parasitic flatworms. The widespread use of PZQ in schistosomiasis endemic areas for about four decades raises concerns about the emergence of resistance of Schistosoma spp. to PZQ under drug selection pressure. This reinforces the urgency in finding alternative therapeutic options that could replace or complement PZQ. We explored the potential of medicinal plants commonly used by indigenes in Kenya for the treatment of various ailments including malaria, pneumonia, and diarrhoea for their antischistosomal properties. Employing the Soxhlet extraction method with different solvents, seven medicinal plants Artemisia annua, Ajuga remota, Bredilia micranta, Cordia africana, Physalis peruviana, Prunus africana and Senna didymobotrya were extracted. Qualitative phytochemical screening was performed to determine the presence of various phytochemicals in the plant extracts. Extracts were tested against Schistosoma mansoni newly transformed schistosomula (NTS) and adult worms and the schistosomicidal activity was determined by using the adenosine triphosphate quantitation assay. Phytochemical analysis of the extracts showed different classes of compounds such as alkaloids, tannins, terpenes, etc., in plant extracts active against S. mansoni worms. Seven extracts out of 22 resulted in <20% viability against NTS in 24 h at 100 μg/ml. Five of the extracts with inhibitory activity against NTS showed >69.7% and ≥72.4% reduction in viability against adult worms after exposure for 24 and 48 h, respectively. This study provides encouraging preliminary evidence that extracts of Kenyan medicinal plants deserve further study as potential alternative therapeutics that may form the basis for the development of the new treatments for schistosomiasis.

This essay introduces the three essays in this collection, “Latin American Studies and the Humanities: One Year Later.” This collection follows our first dossier, “Latin American Studies and the Humanities: Past, Present, Future,” which was published in September 2018 (https://doi.org/10.25222/larr.521). The essays here—all written by historians—address current questions in humanistic research in Latin American and ethnic/area studies, including object-centered analysis, comparative methodologies, and archival formation and practices. Our introduction situates the essays in the dossier within three critical contexts, suggesting how new work in Latin American studies can engage with diverse scholarly paradigms, frameworks, and methodological approaches, specifically oceanic worlds and science studies, ethnic and area studies, and Latinx studies.

Childhood maltreatment is associated with increased risk for most forms of psychopathology. We examine emotion dysregulation as a transdiagnostic mechanism linking maltreatment with general psychopathology. A sample of 262 children and adolescents participated; 162 (61.8%) experienced abuse or exposure to domestic violence. We assessed four emotion regulation processes (cognitive reappraisal, attention bias to threat, expressive suppression, and rumination) and emotional reactivity. Psychopathology symptoms were assessed concurrently and at a 2-year longitudinal follow-up. A general psychopathology factor (p factor), representing co-occurrence of psychopathology symptoms across multiple internalizing and externalizing domains, was estimated using confirmatory factor analysis. Maltreatment was associated with heightened emotional reactivity and greater use of expressive suppression and rumination. The association of maltreatment with attention bias varied across development, with maltreated children exhibiting a bias toward threat and adolescents a bias away from threat. Greater emotional reactivity and engagement in rumination mediated the longitudinal association between maltreatment and increased general psychopathology over time. Emotion dysregulation following childhood maltreatment occurs at multiple stages of the emotion generation process, in some cases varies across development, and serves as a transdiagnostic mechanism linking child maltreatment with general psychopathology.

This essay outlines the three articles in this dossier, “Latin American Studies and the Humanities: Past, Present, Future.” The authors, working in different disciplines, contribute to debates about how to reconceptualize area studies. Each article considers how area studies might be enriched by considering different spatial scales and incorporating methodologies drawn from ethnic studies disciplines. Our introduction explains how each essay contributes to our understanding of five key issues in Latin American studies: (1) the relationship between the field’s regionally bound framework and emerging conceptual paradigms like the global South; (2) the potential for interdisciplinary, rather than multidisciplinary, research; (3) how to place Latin American studies in dialogue with ethnic studies; (4) how to rethink the origins of Latin American studies by tracing the long history of Latin America–generated knowledge about the region; and (5) how recent indigenous studies approaches might decolonize the field of Latin American studies.

What determines citizens’ freedom to exit autocracies? How does this influence global patterns of migration and democratization? Although control over citizen movement has long been central to autocratic power, modern autocracies vary considerably in how much they restrict emigration. This article shows that autocrats strategically choose emigration policy by balancing several motives. Increasing emigration can stabilize regimes by selecting a more loyal population and attracting greater investment, trade and remittances, but exposing their citizens to democracy abroad is potentially dangerous. Using a half-century of bilateral migration data, the study calculates the level and destinations of expected emigration given exogenous geographic and socioeconomic characteristics. It finds that when citizens disproportionately emigrate to democracies, countries are more likely to democratize – and that autocrats restrict emigration freedom in response. In contrast, a larger expected flow of economic emigration predicts autocratic survival and freer emigration policy. These results have important implications for autocratic politics, democratic diffusion and the political sources of migration.

The panel, “Negotiating the Personal and Professional: Ethnomusicologists and Uncomfortable Truths,” presented at the Forty-third ICTM World Conference in Astana, Kazakhstan, grew out of informal conversations common among ethnomusicologists. As practitioners in our discipline, we are involved in complex webs of experience, relationships, and representations focused around music, broadly defined. Our work is inherently social and, when in the field, we develop close relationships with our teachers and consultants as we become comfortable in our sites of research. We are grateful for priceless access to communities and individuals. The intensity and combination of certain relationships and circumstances, however, can lead to conflicting expectations, unanticipated misunderstanding, and situations of personal and professional conflict.

Is territory a trap? Does the concept of territory trap us into false assumptions of internally homogeneous, externally bounded political communities that exercise uniform sovereignty across their domain? Against the background of debates about territory and the territorial state in international relations, this symposium brings together five contributions in political theory that advance a nuanced and systemic understanding of what territory is. Taken together, they indicate that there is much to the territorial paradigm beyond the modern, sovereign, and territorial state model. There are diverse conceptions of territory, which may be relevant across different legal and political orders. The various conceptual analyses of territory in this symposium suggest that the sovereign state model is only one way in which a sovereign political authority can be territorial. These essays provide the conceptual tools to formulate (and subsequently test) the hypothesis that the transformations in statehood may not be best described in terms of the rise and decline of territorial sovereignty, but as moves from one model of territorially bounded political authority to another. In political theory, it is only in recent years that this foundational concept has received sustained attention from political theorists. This symposium aims to take forward this welcome theoretical development.