Participants will be able to describe programs which illustrate the benefits of service-user support.

Drawing an analogy with immigrant and ethnic minority communities, the presenter will argue that there is a value in the mutual support found in identity communities of people who have experienced mental illness.

Ethnic minorities have multiple successful pathways towards social inclusion. They can choose to live, work and socialize in the dominant community, remain in their sub-communities, or move back and forth, choosing activities in each. People with psychiatric disabilities can be offered these same choices: we should not assume that integration into the broader community through mainstreaming is the ultimate goal.

Successful models that build on the value of the mutual support in communities of people with disabilities, such as social firms and the psychosocial clubhouse, will be cited. These models include business incubators that help community members develop micro-businesses and a user-friendly bank to assist in capitalizing such ventures. An economic development approach which identifies enterprises that can advance the economy of the service-user community and offer members work opportunities will be described.

Service-users should be given opportunities to appreciate the mutual support which comes from those with whom they share experiences, concerns, needs and goals, and not feel they must abandon this resource in order to integrate themselves into the broader community.

Electrodermal hyporeactivity has a high sensitivity (up to 97%) and high raw specificity (up to 98%) for suicide.

To evaluate prevalence, sensitivity and specificity of electrodermal hyporeactivity for suicide and suicide attempt, with and without death intent and with violent method or not, in adult patients with a primary diagnosis of depression.

The study will be performed at 20 psychiatric clinical centres in ten European countries. Patients with a primary diagnosis of depression, also in remission, will be recruited. Depressive symptomatology will be assessed through the Montgomery-Asberg Depression Scale. Previous suicide attempts will be registered and the death intent of the worst attempt will be rated according to the first eight items of the Beck Suicide Intent Scale. The risk of suicide will be assessed first according to rules and traditions at the centre and eventually revised considering the results of the EDOR Test (ElectroDermal Orienting Reactivity Test). Through headphones a moderately strong tone is presented now and then during the test. Sensors located within gold electrodes, on which two fingers are connected, are able to register the electrodermal response to those tones, measuring the skin conductance. Sensors also register blood volume variation. Recruited patients will be followed-up for one year. During this test period, information concerning possible suicide attempts or completed suicide will be acquired. Methods used and death intent will be also assessed.

It is expected that the test of electrodermal hyporeactivity detects a previously unknown neuropsychological dysfunction that is independent of the depressive state and can predict suicidality with a high sensitivity and specificity. The EDOR Test is optimized for detecting hyporeactivity and could be easily included into the everyday clinical practice.

To describe therapeutic features of 120 panic disorder (PD) patients treated with clonazepam, paroxetine, or clonazepam + paroxetine for 3 years and their follow-up for more 6 years.

A prospective open study randomized 120 PD patients to 2 mg/day clonazepam or 40 mg/day paroxetine. Poor responders were switched after 8 weeks to combined treatment with ∼2 mg/day clonazepam + ∼40 mg/day paroxetine. Tapered withdrawal of all treatments was performed after 3 years. Efficacy, safety, and cumulative relapse and remission were studied over the following 6 years, using panic attack (PA) count, clinical global impression-severity (CGI-S), and Hamilton anxiety scale (HAMA).

94 patients completed 3 years treatment. All were free of panic attacks since at least one year before undergoing tapered drug withdrawal. After two months of tapering, 80% of clonazepam patients were drug-free, versus 55% on paroxetine. No serious or severe adverse event were observed but PA/month, CGI-S, and HAMA worsened slightly. In annually studied patients the relapse rates were similar after the 3 treatments with an advantage of clonazepam over the combination (p=0.0035) and paroxetine (p=0.08, exact Fisher) at the first year after drug withdrawal. Cumulative relapses rate were 41%, 77%, and 94% at years 1, 4, and 6, but relapse therapy with either clonazepam or paroxetine was successful in nearly all cases.

PD is a chronic disorder, with many patients relapsing after 3 years treatment. Response to retreatment was excellent. Paroxetine and clonazepam were associated with similar long-term prognoses but clonazepam was better tolerated.

Social anxiety disorder (SAD) is a strong risk factor for the development of depressive disorders (major depressive disorder or dysthymia).

Identification of blood-based molecular predictors of a subsequent depressive episode in SAD.

Objectives: To screen SAD patient serum for biomarkers which predict the onset of depressive disorders over a 2-year follow-up period.

Multiplexed-immunoassay data obtained from 143 SAD patients without co-morbid depressive disorders, recruited within the Netherlands Study of Depression and Anxiety (NESDA), were investigated. The serum screen included 165 mainly immunological, metabolical and hormonal analytes. Predictive performance of identified biomarkers and clinical variables (e.g. Beck Anxiety Inventory) was assessed using receiver operating characteristics curves (ROC) and represented by the area under the ROC curve (AUC). Stepwise logistic regression was used to select an optimal set of patient parameters, combining predictive serum analytes and clinical variables.

A set of four serum analytes and four associated clinical variables reached an AUC of 0.86 for the identification of SAD individuals, who developed a subsequent depressive episode. Throughout our analyses, biomarker panels yielded superior discriminative performance compared to clinical variables alone.

We report the discovery of a serum marker panel with good predictive performance to identify SAD individuals prone to develop depressive disorders in a naturalistic cohort design. Furthermore, we emphasise the importance to combine biological markers and clinical parameters for disease course predictions in psychiatry. Validated biomarkers could help to identify SAD patients at risk of a depressive episode, thus facilitating early treatment and improving clinical outcome.

Using meta-analysis and physician billing data, the prevalence and efficacy of treatments for anxiety disorders in children and adolescents was elucidated.

To use billing data from the Calgary Health Region (CHR) to determine anxiety disorder prevalence rates. Meta-analysis was performed to compare treatment efficacy of two leading interventions for anxiety disorders in youth.

We sought to examine the prevalence of anxiety disorders in the CHR, and evaluate the efficacy of cognitive behavioural therapy (CBT) and attention bias modification (ABM) for the treatment of anxiety disorders in youth.

Physician billing data was used to identify 303 938 unique individuals diagnosed with an anxiety disorder. Effect sizes for CBT/ABM treatments were calculated for clinician and self-report measures and displayed in forest plots, allowing comparison of treatment efficacy.

The 16-year cumulative anxiety disorder prevalence rate was 28.8% in the CHR, while the annual rate increased from 1.5% to 2.1% from 1994 to 2009. There was no evidence of efficacy for the ABM treatment. 80% of the CBT studies showed efficacy of the treatment as rated by clinicians, but none showed significant improvement in self-report measures. Analysis revealed the ABM placebo was more effective than ABM, and significantly more efficacious than CBT.

The prevalence of anxiety disorders in the CHR increased by 40% from 1993 to 2009. Meta-analysis revealed no evidence of efficacy for ABM. CBT only showed efficacy in terms of clinician-rated measures; possible evidence of clinician bias. Ultimately, revision of current ABM methods is necessary.

Longitudinal alcohol consumption in early adulthood has been studied, but reports from later adulthood are scarce.

Finding longitudinal trends in alcohol consumption using prospective birth cohort data.

To investigate trends in self-reported alcohol consumption in adulthood.

In the Northern Finland Birth Cohort 1966 (N=5,621) alcohol use was studied with questionnaires at ages 31 and 46. Participants were classified into steady drinkers, increasers and decreasers based on the change in consumption (g/day). Multinomial regression analysis was conducted with educational, marital and employment baseline statuses and their changes, and baseline alcohol use as factors influencing the change in alcohol consumption.

70% of alcohol users were classified as steady drinkers, 10% as decreasers and 20% as increasers. In all, daily alcohol consumption rose over 30%, particularly among women. The unemployed, singles and low-educated consumed the most (P<0.01). Being a divorced male (OR 1.5; 95%CI: 1.0-2.1) or a long-term unemployed female (1.6; 1.0-2.6) predicted increase in alcohol use. The probability of decrease was higher among single men (OR 1.6; 1.0-2.4) and women (2.8; 1.7-4.4) at 31y, among men entering a relationship (1.9; 1.2-3.1), and among divorced women (2.4; 1.4-3.8) and entering a relationship (2.1; 1.3-3.5).

Alcohol usage among middle-aged Northern Finns is rather stable and increase is more exhibited than decrease. Gender differences in predictors existed: changes in relationship status predicted decrease in usage in women, whereas in men divorce predicted increase in usage and a new relationship predicted decrease. Long-term unemployment predicted increase only in women.

Adolescents with a problematic use of the Web reported less satisfaction also in interpersonal relationships and poorer onces with their parents (Liu & Kou, 2007). Other studies have shown that attachment plays a role in the way in which the person interacts with others in the network (Buote et.al. 2009).

This study was focused on the psychological profile of a sample of young Facebook users and on the relationships between the time spent on the Web, symptoms detected by the SLC-90, the state of attachment (Ca-Mir), and the self perception of attachment to parents and friends.

500 adolescents (F = 221, M = 214), aged between 13 and 18 years, were assessed by means of self rating questionnaires (BFAS Over-Bergen Facebook Addiction Scale, SPQ – Shorter Promis Questionnaire, MPIQ – Mobile Phone Involvement Questionnaire, UCLA – Loniless Scale, Self-Disclosure Online, IPPA – Inventory of Parent and Peer Attachment, SCL-90 – Syntom Check List, Ca-mir). On two subjects was performed EEG recording, during exposure to stimuli related to Facebook and to the Web.

A subgroup of young people were spending more time on the Web and were also reporting situations of mental and emotional vulnerability asociated with dysfunction in family relationships.

These results emerge from profiles of normality and risk, even multiples, which relate the quality of parent-child attachment relationship and the proper use of social networks and the Internet in general. Further investigations are needed to fully understand the brain dynamics behind these profiles.

Physical comorbidities are common in patients with mental illness and substance use disorder. Both regular use of alcohol and cannabis have been associated with adverse health effects. However, their physical comorbidities can also be explained by other unhealthy lifestyle choices, i.e. lack of physical activity, poor nutrition and smoking.

The aim of this study is to analyse baseline and follow up data after one and a half year of a 3-year interventional programme of improvement of physical health in patients with mental illness and comorbid substance use disorder.

All patients with mental illness and substance use disorder referred to Department M at Aarhus University Hospital Risskov, Denmark from 1 July 2013 and onwards are included in the programme. The study takes an active awareness and motivational interviewing approach to increase knowledge and understanding of physical health problems. The intervention includes health promotion activities, and physical health parameters are monitored. Further guidance on healthy food intake, smoking cessation and a physically active life is provided.

50 patients are expected to be participating in the programme after one and a half year. Preliminary results after one-year show that 89,7 % smoke cigarettes, their level of physical activity is low, which is seen in the extent of their sedentary behaviour. Further there are problems with insufficient food intake among patients.

This study indicates, that patients with mental illness and comorbid substance use disorder need guidance on a healthier lifestyle. They show an interest in this interventional programme.

Our knowledge about the effect of internet use on patients with psychotic disorder has not been fully investigated.

The main objective was to investigate the psychological characteristics associated with Internet use in chronically mentally ill, compared to the general population.

To explore the levelsof internet use in patients with psychosis and their association with self-esteemand interpersonal relationships.

The study involved 101 participants of which 30 were psychotic outpatients (meanage 39 years, SD = 11) and 71 (mean age 34 years, SD = 8) from the generalpopulation. Participants filled out a questionnaire of a) social-demographicand clinical parameters b) Diagnostic criteria Young's Internet addiction, c) Internet Addiction Test (IAT) questionnaire for the diagnosis of Internet addiction, d) The Scale in Interpersonal Relationships (ECRI) and e) The Greek version of Self-esteem Questionnaire (SES, Self-Esteem Scale).

We found significant statistical differences in terms of internetaddiction (Young's diagnostic criteria: 5/25 vs 6/65, p<.00001 and IAT: 7/23 vs 8/63, p<.00001) when we compared patients with psychotic disorder with general population. Especially, for psychotic patients logistic regression models found that self-esteem, avoidance and anxiety adulthood relationships statistically contributed to internet addiction, after adjustments(p=043, p=.015 and p=.021, respectively).

Our results found that a psychotic patient with difficulty ininterpersonal relationships and with low self-esteem is more likely to adopt an addictive behavior in the use of internet in comparison to the general population.

Faut-il veiller sur une crise suicidaire dès lors qu’un sujet a été rencontré au décours d’une TS ? Nous prônons la simple idée de revenir un peu à distance, sur le compromis de sortie des urgences qui avait été conclu avec le patient suicidant. Nous présentons l’enchaînement des recherches internationales et françaises, quantitatives et qualitatives, qui nous permet aujourd’hui de proposer de tester un nouveau dispositif de soins.

Revue d’essais thérapeutiques randomisés comparatifs. L’objectif principal était pour tous la réduction des conduites suicidaires à 6 ou 12 mois, en comparaison d’un groupe contrôle sans intervention spécifique. Un focus particulier sur le PHRC ALGOS et son étude qualitative et sociologique : ÉQUATION.

L’efficacité de l’algorithme baptisé ALGOS, jointe aux appropriations par les patients et les partenaires de soin des éléments du processus de veille, nous permettent de proposer un nouveau dispositif de suivi posthospitalier des suicidants : Vigilan S. Ce dispositif associe une « carte ressource prévention » en 0 800 distribuée à tous suicidants quittant le système hospitalier, un suivi téléphonique plus intensifié pour les patients ayant déjà connu une TS auparavant et un rappel téléphonique de tous à 6 mois. Le dispositif est centralisé pour une région donnée et un partenariat très étroit a été tissé avec les Samu/centre 15 qui accueillent les recontacteurs.

Ce programme se déploie en Nord–Pas-de-Calais depuis le début de cette année et 24 sites sont déjà associés au programme ; en cette fin d’année 2015, 4 autres régions rejoignent le NPC pour un essai populationnel pilote de trois ans, au terme desquelles la DGS associée à la CNAMTS prendront la décision ou non de proposer sa généralisation à tout le territoire français.