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We study a distributionally robust reinsurance problem with the risk measure being an expectile and under expected value premium principle. The mean and variance of the ground-up loss are known, but the loss distribution is otherwise unspecified. A minimax problem is formulated with its inner problem being a maximization problem over all distributions with known mean and variance. We show that the inner problem is equivalent to maximizing the problem over three-point distributions, reducing the infinite-dimensional optimization problem to a finite-dimensional optimization problem. The finite-dimensional optimization problem can be solved numerically. Numerical examples are given to study the impacts of the parameters involved.
Neuronal intranuclear inclusion disease (NIID) is a rare slowly progressive neurodegenerative disorder that is characterized pathologically by the presence of eosinophilic intranuclear inclusions. NIID is a heterogeneous disease with diverse clinical manifestations, making diagnosis difficult. Here, we analyzed the clinical, pathological, and radiological features of Chinese NIID patients to improve our understanding of NIID.
Methods:
A total of 17 patients with sporadic NIID were recruited from the Ruijin Hospital Database between 2014 and 2021. Clinical patient information and brain MRI data were collected. All of the patients underwent standard skin biopsy procedures.
Results:
The average age of onset for symptoms was 60.18 years, and the average duration of illness was 4.06 years. All patients were diagnosed with NIID due to the presence of intranuclear inclusions confirmed by skin biopsy. Tremor was the most common initial symptom. The average ages at onset and at diagnosis were both lower in patients with tremor than in patients without tremor. NIID may be a systemic disease that affects multiple organs, for one patient had a history of chronic renal insufficiency for more than 10 years. In addition to high-intensity U-fibers signals on diffusion-weighted imaging, there were several other MRI findings, such as focal leukoencephalopathy and cortical swelling. Encephalitic episodes followed by reversible leukoencephalopathy was another important imaging feature of NIID.
Conclusion:
The clinical manifestations of NIID are highly variable. Tremor may be the most common initial symptom in certain cohorts. Encephalitic episodes followed by reversible asymmetric leukoencephalopathy may also indicate this disease.
This paper addresses fixed-time trajectory tracking for a dual-arm free-floating space robot (FFSR) with the large initial errors and bounded uncertainty. A wrist-based trajectory planning method is improved by fixed-time stability to fast eliminate the error caused by singularity. Then, a novel low-chattering and global-nonsingular fixed-time terminal sliding mode control strategy is studied by state approaching angle and switching sliding mode; the practical fixed-reachable Lyapunov stability analysis is presented for a mechanical control system. In the end, the proposed trajectory planning method and controller are combined to improve the tracking accuracy of end-effector to the nanoscale. Simulation results validate the effectiveness of the proposed methodologies.
Data on average iodine requirements for the Chinese population are limited following implementation of long-term universal salt iodisation. We explored the minimum iodine requirements of young adults in China using a balance experiment and the ‘iodine overflow’ hypothesis proposed by our team. Sixty healthy young adults were enrolled to consume a sequential experimental diet containing low, medium and high levels of iodine (about 20, 40 and 60 μg/d, respectively). Each dose was consumed for 4 d, and daily iodine intake, excretion and retention were assessed. All participants were in negative iodine balance throughout the study. Iodine intake, excretion and retention differed among the three iodine levels (P < 0·01 for all groups). The zero-iodine balance derived from a random effect model indicated a mean iodine intake of 102 μg/d, but poor correlation coefficients between observed and predicted iodine excretion (r 0·538 for μg/d data) and retention (r 0·304 for μg/d data). As iodine intake increased from medium to high, all of the increased iodine was excreted (‘overflow’) through urine and faeces by males, and 89·5 % was excreted by females. Although the high iodine level (63·4 μg/d) might be adequate in males, the corresponding level of 61·6 μg/d in females did not meet optimal requirements. Our findings indicate that a daily iodine intake of approximately half the current recommended nutrient intake (120 μg/d) may satisfy the minimum iodine requirements of young male adults in China, while a similar level is insufficient for females based on the ‘iodine overflow’ hypothesis.
We study a weighted comonotonic risk-sharing problem among multiple agents with distortion risk measures under heterogeneous beliefs. The explicit forms of optimal allocations are obtained, which are Pareto-optimal. A necessary and sufficient condition is given to ensure the uniqueness of the optimal allocation, and sufficient conditions are given to obtain an optimal allocation of the form of excess of loss or full insurance. The optimal allocation may satisfy individual rationality depending on the choice of the weight. When the distortion risk measure is value at risk or tail value at risk, an optimal allocation is generally of the excess-of-loss form. The numerical examples suggest that a risk is more likely to be shared among agents with heterogeneous beliefs, and the introduction of the weight enables us to prioritize some agents as part of a group sharing a risk.
The twinning and slip modes of a rolled magnesium alloy sheet were investigated through quasi-in-situ tensile tests that were carried out along the rolling direction at room temperature with a constant strain rate. Scanning electron microscopy and electron backscattered diffraction observations were used to identify activated twinning and slip systems. Schmid factors were calculated to analyze different deformation modes. The analyses show that a small number of {10-12} tensile twins were present during deformation, and these twins resulted from the accommodation of compression along the tensile direction. Post-deformation examination revealed the dominance of prismatic <a> slip.
Timing of seedling emergence is a critical aspect of a plant's life cycle, and it may influence the expression of other plant life history traits. However, most studies have been conducted at the population level, and thus little is known about timing of seedling emergence at the community level. In the field, we determined the peak emergence season for seedlings of 144 species collected from a subalpine meadow on the eastern Tibet Plateau in China. The proportion of species with seedlings emerging in autumn, spring and summer, seedling field emergence percentage (FE) and mean emergence time (MET) were analysed in relation to seed mass, life cycle type (annual/biennial and perennial) and phylogeny. The results showed that (1) the proportion of species with seedlings emerging in autumn (33%), spring (44%) and summer (23%) differed significantly; (2) overall, species with seedlings emerging in autumn had higher FE than those emerging during spring/summer; (3) there was a positive relationship between log-seed mass and log-MET, but log-seed mass had no significant effect on log-FE; (4) life cycle type did not affect seedling emergence; and (5) phylogeny significantly explained peak emergence season. These results suggest that seed mass and phylogenetic position are the main determinants of seedling emergence season. However, seedling peak emergence season affected FE, growing season length and resource utilization, and thus may be related to the importance of a species in the community.
Previous studies have supported the theory that there is a positive association between ferritin and carotid atherosclerosis in Western people. Diet plays an important role in determining serum ferritin concentration. Asian dietary patterns are different from Western dietary patterns, implying that there may be a difference in the association of ferritin with carotid atherosclerosis between Asian and Western people. However, few studies focus on the association between ferritin and carotid atherosclerosis among Asians. The aim of this study was to investigate how serum ferritin levels are associated with carotid atherosclerosis in an Asian adult population. A cross-sectional assessment was performed in 8302 adults in Tianjin, China. Carotid intima-media thickness (IMT) and plaques were assessed using ultrasonography, and serum ferritin was measured using the protein chip-chemiluminescence method. Multiple logistic regression analysis was used to examine the association between quartiles of serum ferritin concentration and carotid atherosclerosis. In the present study, the overall prevalence of IMT and carotid plaques in participants is 29·2 and 22·7 %, respectively. In women, after adjustments for potentially confounding factors, the OR of IMT and carotid plaques by increasing serum ferritin quartiles were 1·00, 1·39 (95 % CI 0·98–1·99), 1·39 (95 % CI 0·99–1·97), 1·81 (95 % CI 1·30–2·55) (Pfor trend<0·001) and 1·00, 1·24 (95 % CI 0·89–1·73), 1·18 (95 % CI 0·85–1·65), 1·59 (95 % CI 1·15–2·20) (Pfor trend<0·01), respectively. However, no association was found between serum ferritin and carotid atherosclerosis in men. The study demonstrated that increased serum ferritin levels are independently associated with IMT and carotid plaques in Asian women but not in Asian men.
We bring the recently developed framework of dependence uncertainty into collective risk models, one of the most classic models in actuarial science. We study the worst-case values of the Value-at-Risk (VaR) and the Expected Shortfall (ES) of the aggregate loss in collective risk models, under two settings of dependence uncertainty: (i) the counting random variable (claim frequency) and the individual losses (claim sizes) are independent, and the dependence of the individual losses is unknown; (ii) the dependence of the counting random variable and the individual losses is unknown. Analytical results for the worst-case values of ES are obtained. For the loss from a large portfolio of insurance policies, an asymptotic equivalence of VaR and ES is established. Our results can be used to provide approximations for VaR and ES in collective risk models with unknown dependence. Approximation errors are obtained in both cases.
Glyphosate-resistant (GR) horseweed has become an especially problematic
weed in different crop production systems across the United States and the
world. In this field study, we used a nondestructive measurement system to
analyze the pollen production, deposition, and dispersion of a Tennessee
glyphosate resistant (TNR) horseweed biotype in Knoxville, TN during the
2013 pollination season. We observed that the pollination season of TNR
horseweed lasted about 2 mo (54 d). About 78.93% of horseweed pollen was
released between 9:00 A.M. and 7:00 P.M. during each sampling day and the
release peak was at about 1:30 P.M. The seasonal release of pollen grains
was estimated to be 5.11 million grains plant−1. The release rate
data indicated that the integrated horizontal flux density and deposition
flux density contributed to 78.17% and 21.83% of the release rate,
respectively. We also found that pollen concentration decreased with
distance from the source field; the average pollen concentration decreased
to 50.69% at a distance of 16 m from the source plot. This is the first
result of a systematic, direct examination of the release rate (emission and
deposition), release pattern (daily and seasonal), and dispersion pattern of
GR horseweed pollen.
Recent studies have shown that chemical immiscibility is important to achieve enhanced radiation tolerance in metallic multilayers as immiscible layer interfaces are more stable against radiation induced mixing than miscible interfaces. However, as most of these immiscible systems have incoherent interfaces, the influence of coherency on radiation resistance of immiscible systems remains poorly understood. Here, we report on radiation response of immiscible Cu/Fe multilayers, with individual layer thickness h varying from 0.75 to 100 nm, subjected to He ion irradiation. When interface is incoherent, the peak bubble density decreases with decreasing h and reaches a minimum when h is 5 nm. At even smaller h when interface is increasingly coherent, the peak bubble density increases again. However, void swelling in coherent multilayers with smaller h remains less than those in incoherent multilayers. Our study suggests that the coherent immiscible interface is also effective to alleviate radiation induced damage.
InGaN/GaN green light-emitting diodes (LEDs) have been prepared by metal-organic chemical vapor deposition with various growth temperatures for p-GaN layer. The structural and optoelectronic properties of as-grown multiple quantum wells (MQWs) and LEDs are studied in detail. It reveals that with the growth of p-GaN layer, the crystalline qualities of the as-grown n-GaN layer are improved significantly, while the optoelectronic properties of MQWs are decreased dramatically. Furthermore, the mechanisms for the effect of p-GaN growth temperature on the properties of InGaN/GaN green LEDs are proposed. It is demonstrated that the p-GaN layer grown at a suitable temperature of 950 °C shows the highest optoelectronic properties due to the fact that this suitable temperature for p-layer growth is good for the Mg doping and would not cause the fluctuation of indium in the MQWs, and eventually benefits to the effective recombination of carriers. This work provides an optimized p-GaN layer growth temperature for realizing highly efficient InGaN/GaN green LED devices.
The properties of a series of phase measurement techniques, including interferometry, the Hartmann–Shack wavefront sensor, the knife-edge technique, and coherent diffraction imaging, are summarized and their performance in high power laser applications is compared. The advantages, disadvantages, and application ranges of each technique are discussed.
Site selection for Antarctic research stations is of great importance and is necessary to support Antarctic expeditions. Site selection is affected by both the scientific investigations planned and the expected life of stations following construction. In the site allocation process, an efficient spatial data management system is required to manage various criteria and a robust allocation method is important to handle decision uncertainties. The aim of this study was to build a criteria system and to conduct a site selection process with aid from geographical information systems (GIS) and the fuzzy analytical hierarchy process (FAHP). In considering the natural environment and building conditions, fifteen factors were used as multiple evaluation sub-criteria and grouped into four main criteria: scientific research, environment, logistical support and topography. Comparisons were made between potentially suitable areas and the locations of existing stations and camps to demonstrate fitness-for-use of the allocation results. Finally, the suitability map was applied to identify candidate sites for a new Chinese research station by considering the position of current stations and areas of scientific interest. This model offers a comprehensive methodology for decision-makers in the assessment of potential Antarctic research station sites.
We aimed to assess and compare the behavioural and emotional outcomes of school-aged children after surgery or transcatheter closure for ventricular septal defect and investigate the risk factors for developing abnormal behavioural problems with the condition.
Methods
In this study, we included 29 children, including 20 boys, with ventricular septal defect who underwent surgery and 35 children, including 21 boys, who underwent transcatheter closure (6–13 years old) and their age- and sex-matched best friends (n = 56) and their parents. The Child Behavior Checklist was used to obtain standardised parents’ reports of behavioural and emotional problems in children. The 28-item version of the General Health Questionnaire was used to assess parents’ psychological distress. Pearson correlation and logistic regression were used to analyse risk factors for developing behaviour problems.
Results
Behavioural problems were greater for boys and girls undergoing surgery or transcatheter closure than controls. The behavioural problems were mainly depression, somatic complaints, and social withdrawal for boys and thought problems, depression, somatic complaints, and social withdrawal for girls. Depression and somatic complaints were greater for boys undergoing surgery than for boys undergoing transcatheter closure. Behavioural problems did not differ between treatment groups for girls. Risk factors for developing behavioural problems were age at the time of ventricular septal defect repair (p = 0.03; odds ratio = 2.35), skin scar (p = 0.04; odds ratio = 3.12), post-operative atrioventricular block (p = 0.03; odds ratio = 2.81), and maternal anxiety (p < 0.01; odds ratio = 4.5).
Conclusion
School-aged children who underwent repair of ventricular septal defect regardless of the type of treatment (surgery or transcatheter closure) exhibit internalising behavioural problems. Risk factors for developing problems are young age, scarring, post-operative atrioventricular block, and maternal anxiety. In particular, maternal anxiety is the most important risk factor.
Electropulsing treatment (EPT) has been first applied to the recrystallization of a refractory metal—tungsten (W). We have three major observations: (i) the recrystallization temperature of a rolled pure W under EPT is ∼900 K higher than its conventional recrystallization temperature (1603 K); (ii) the time required for recrystallization is significantly reduced compared with that of conventional heat treatment (CHT); (iii) the recrystallized grains are also much finer than the ones under CHT. Based on quantitative analysis, we conclude that the huge increase of the recrystallization temperature of the rolled pure W under EPT is due to the high heating rate generated by EPT and high activation energy for vacancy diffusion of W, and the accelerated recrystallization and grain refinement have resulted from the coupling of thermal and electromigration effects of EPT at relatively high temperatures.
The emergence of tap water supplied through water grids changed the spatial structure of cities. As a commercial port containing foreign settlements and divided urban political systems, Tianjin became host to two major, long-term water supply systems. Different social environments and systems of municipal government meant that tap water was accepted by urban society in different ways. In the settlements, the supply of tap water was the foundation for the formation of a modern community. In the Old City, the introduction of tap water for the most part had a different effect: it manifested the ways in which traditional and new lifestyles conflicted and mingled with each other. Yet, in any case, as tap water entered the lives of the people from the end of the Qing to the Republican period, new ideas of health and hygiene associated with tap water were gradually accepted, and modern urban lifestyles gradually took shape.
The decomposition mechanism of block copolymer templates inside as-synthesized mesostructured solids has been systematically studied using solid-state 1H magic angle spinning nuclear magnetic resonance spectroscopy, thermogravimetric analysis, and high-vacuum Fourier transform infrared spectrometry. It is shown that there exists hydrogen-bonding interaction between silanols and block copolymers at the inorganic–organic interface in the self-assembled as-synthesized mesostructured solids, which plays an important role in protecting the surfactants against decomposition during the high-temperature hydrothermal treatment process. Increasing silanol concentration can enhance the hydrogen-bonding interaction and thus shows better “protection” effect. Moreover, the thermal decomposition of the block copolymer in as-synthesized mesostructured solids in air commences at higher temperatures compared with that in acidic solution or in air, providing further evidence in support of the silanol protection mechanism.
The stress relaxation responses of the Sn–3.8Ag–0.7Cu joints following exposure to electrical currents were examined to investigate the effect of electromigration on the reliability of solder joints. It was found that the stress relaxation rate was enhanced for the Sn–3.8Ag–0.7Cu solder joints subjected to a current density of 2 × 104 A/cm2. Sn hillock formation was observed in situ on the surface of the solder joint and the increase of the hillock volume was obtained as a function of the current application time. Analysis of the vacancy flux indicated that the variations of the vacancy concentration with the electromigration time from the calculations agreed with the growth kinetics of the hillocks observed in the experiments. By modeling the stress relaxation as a climb-assisted dislocation glide process, it is shown that the vacancy accumulation induced by electromigration enhanced the dislocation climb rate, resulting in a large increase of the stress relaxation rate.
We made photonic crystals composed of artificial opals infiltrated with ZnS semiconductor nanocrystals by using self-assembly and solvothermal methods. Scanning electron microscopy images show that the silica spheres exhibit a well-ordered arrangement and the ZnS nanocrystals grow homogenously inside the opal matrix and the as-synthesized ZnS nanocrystals reveal a cubic phase from X-ray diffraction pattern. Furthermore, the optical properties of the infiltrated opals with different ZnS filling ratio are also studied by transmission spectroscopy respectively. It is proposed that the position of the stop band can be easily designed by controlling the infiltration ratio of ZnS. These results demonstrate an effective and practical route to obtain high-performance photonic crystal structures.
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