Gravitational waves from coalescing neutron stars encode information about nuclear matter at extreme densities, inaccessible by laboratory experiments. The late inspiral is influenced by the presence of tides, which depend on the neutron star equation of state. Neutron star mergers are expected to often produce rapidly rotating remnant neutron stars that emit gravitational waves. These will provide clues to the extremely hot post-merger environment. This signature of nuclear matter in gravitational waves contains most information in the 2–4 kHz frequency band, which is outside of the most sensitive band of current detectors. We present the design concept and science case for a Neutron Star Extreme Matter Observatory (NEMO): a gravitational-wave interferometer optimised to study nuclear physics with merging neutron stars. The concept uses high-circulating laser power, quantum squeezing, and a detector topology specifically designed to achieve the high-frequency sensitivity necessary to probe nuclear matter using gravitational waves. Above 1 kHz, the proposed strain sensitivity is comparable to full third-generation detectors at a fraction of the cost. Such sensitivity changes expected event rates for detection of post-merger remnants from approximately one per few decades with two A+ detectors to a few per year and potentially allow for the first gravitational-wave observations of supernovae, isolated neutron stars, and other exotica.

Glyphosate-tolerant and glyphosate-resistant weeds are becoming increasingly problematic in cotton fields in Australia, necessitating a return from a glyphosate dominated system to a more integrated approach to weed management. The development of an integrated weed management system can be facilitated by identifying the critical period for weed control (CPWC), a model that enables cotton growers to optimize the timing of their weed control inputs. Using data from field studies conducted from 2003 to 2015, CPWC models using extended functions, including weed biomass in the relationships, were developed for the mimic weeds, common sunflower and Japanese millet, in high-yielding, fully irrigated cotton. A multispecies CPWC model was developed after combining these data sets with data for mungbean in irrigated cotton, using weed height and weed biomass as descriptors in the models. Comparison of observed and predicted relative cotton-lint yields from the multispecies CPWC model demonstrated that the model reasonably described the competition from these three very different mimic weeds, opening the possibility for cotton growers to use a multispecies CPWC model in their production systems.

Research using the critical period for weed control (CPWC) has shown that high-yielding cotton crops are very sensitive to competition from grasses and large broadleaf weeds, but the CPWC has not been defined for smaller broadleaf weeds in Australian cotton. Field studies were conducted over five seasons from 2003 to 2015 to determine the CPWC for smaller broadleaf weeds, using mungbean as a mimic weed. Mungbean was planted at densities of 1, 3, 6, 15, 30, and 60 plants m−2 with or after cotton emergence and added and removed at approximately 0, 150, 300, 450, 600, 750, and 900 degree days of crop growth (GDD). Mungbean competed strongly with cotton, with season-long interference; 60 mungbean plants m−2 resulted in an 84% reduction in cotton yield. A dynamic CPWC function was developed for densities of 1 to 60 mungbean plants m−2 using extended Gompertz and exponential curves including weed density as a covariate. Using a 1% yield-loss threshold, the CPWC defined by these curves extended for the full growing season of the crop at all weed densities. The minimum yield loss from a single weed control input was 35% at the highest weed density of 60 mungbean plants m−2. The relationship for the critical time of weed removal was further improved by substituting weed biomass for weed density in the relationship.

Field studies were conducted over five seasons from 2004 to 2015 to determine the critical period for weed control (CPWC) in high-yielding, irrigated cotton using a competitive mimic grass weed, Japanese millet. Japanese millet was planted with or after cotton emergence at densities of 10, 20, 50, 100, and 200 plants m−2. Japanese millet was added and removed at approximately 0, 150, 300, 450, 600, 750, and 900 degree days of crop growth (GDD). Data were combined over years. Japanese millet competed strongly with cotton, with season-long interference resulting in an 84% reduction in cotton yield with 200 Japanese millet plants m−2. The data were fit to extended Gompertz and logistic curves including weed density as a covariate, allowing a dynamic CPWC to be estimated for densities of 10 to 200 Japanese millet plants m−2. Using a 1% yield-loss threshold, the CPWC commenced at 65 GDD, corresponding to 0 to 7 d after crop emergence (DAE), and ended at 803 GDD, 76 to 98 DAE with 10 Japanese millet plants m−2, and 975 GDD, 90 to 115 DAE with 200 Japanese millet plants m−2. These results highlight the high level of weed control required throughout the cropping season in high-yielding cotton to ensure crop losses do not exceed the cost of weed control.

We employ global input–output analysis to quantify amplification of exogenous disturbances in compressible boundary layer flows. Using the spatial structure of the dominant response to time-periodic inputs, we explain the origin of steady reattachment streaks in a hypersonic flow over a compression ramp. Our analysis of the laminar shock–boundary layer interaction reveals that the streaks arise from a preferential amplification of upstream counter-rotating vortical perturbations with a specific spanwise wavelength. These streaks are associated with heat-flux striations at the wall near flow reattachment and they can trigger transition to turbulence. The streak wavelength predicted by our analysis compares favourably with observations from two different hypersonic compression ramp experiments. Furthermore, our analysis of inviscid transport equations demonstrates that base-flow deceleration contributes to the amplification of streamwise velocity and that the baroclinic effects are responsible for the production of streamwise vorticity. Finally, the appearance of the temperature streaks near reattachment is triggered by the growth of streamwise velocity and streamwise vorticity perturbations as well as by the amplification of upstream temperature perturbations by the reattachment shock.

We compared systematic and random survey techniques to estimate breeding population sizes of burrow-nesting petrel species on Marion Island. White-chinned (Procellaria aequinoctialis) and blue (Halobaena caerulea) petrel population sizes were estimated in systematic surveys (which attempt to count every colony) in 2009 and 2012, respectively. In 2015, we counted burrows of white-chinned, blue and great-winged (Pterodroma macroptera) petrels within 52 randomized strip transects (25 m wide, total 144 km). Burrow densities were extrapolated by Geographic Information System-derived habitat attributes (geology, vegetation, slope, elevation, aspect) to generate island-wide burrow estimates. Great-winged petrel burrows were found singly or in small groups at low densities (2 burrows ha−1); white-chinned petrel burrows were in loose clusters at moderate densities (3 burrows ha−1); and blue petrel burrows were in tight clusters at high densities (13 burrows ha−1). The random survey estimated 58% more white-chinned petrels but 42% fewer blue petrels than the systematic surveys. The results suggest that random transects are best suited for species that are widely distributed at low densities, but become increasingly poor for estimating population sizes of species with clustered distributions. Repeated fixed transects provide a robust way to monitor changes in colony density and area, but might fail to detect the formation/disappearance of new colonies.

Field studies were conducted over six seasons to determine the critical period for weed control (CPWC) in high-yielding cotton, using common sunflower as a mimic weed. Common sunflower was planted with or after cotton emergence at densities of 1, 2, 5, 10, 20, and 50 plants m−2. Common sunflower was added and removed at approximately 0, 150, 300, 450, 600, 750, and 900 growing degree days (GDD) after planting. Season-long interference resulted in no harvestable cotton at densities of five or more common sunflower plants m−2. High levels of intraspecific and interspecific competition occurred at the highest weed densities, with increases in weed biomass and reductions in crop yield not proportional to the changes in weed density. Using a 5% yield-loss threshold, the CPWC extended from 43 to 615 GDD, and 20 to 1,512 GDD for one and 50 common sunflower plants m−2, respectively. These results highlight the high level of weed control required in high-yielding cotton to ensure crop losses do not exceed the cost of control.

Crop plants have been used as mimic weeds to substitute for real weeds in competition studies. These mimic weeds have the advantages of availability of seed, uniform germination and growth, and the potential to confer better experimental controllability and repeatability. However, the underlying assumption that the competitive effects of mimic weeds are similar to real weeds has not been tested. We compared a range of morphological traits (plant height, node and leaf number, leaf area, leaf size, and dry weight) between the mimic weeds and real weeds: Japanese millet vs. junglerice, mungbean vs. bladder ketmia, and common sunflower vs. fierce thornapple. The impact of these mimic and real weeds on cotton was also assessed. There were similarities and differences between the mimic and real weeds, but impact on cotton lint yield was most closely associated with weed height and dry weight at mid-season. Mimic weeds may be satisfactorily substituted for real weeds in competition experiments where seasonal and environmental conditions are not limiting, such as with fully irrigated cotton, provided the plants have similar dry weight and height at mid-season. Alternatively, one can account for the differences in dry weight and height. We define here a generalized relationship estimating the yield loss of high-yielding, irrigated cotton from weed competition over a range of weed dry weights and heights, allowing extrapolation from the results with mimic weeds to the competitive effects of a range of weeds.

The role that vitamin D plays in pulmonary function remains uncertain. Epidemiological studies reported mixed findings for serum 25-hydroxyvitamin D (25(OH)D)–pulmonary function association. We conducted the largest cross-sectional meta-analysis of the 25(OH)D–pulmonary function association to date, based on nine European ancestry (EA) cohorts (n 22 838) and five African ancestry (AA) cohorts (n 4290) in the Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium. Data were analysed using linear models by cohort and ancestry. Effect modification by smoking status (current/former/never) was tested. Results were combined using fixed-effects meta-analysis. Mean serum 25(OH)D was 68 (sd 29) nmol/l for EA and 49 (sd 21) nmol/l for AA. For each 1 nmol/l higher 25(OH)D, forced expiratory volume in the 1st second (FEV1) was higher by 1·1 ml in EA (95 % CI 0·9, 1·3; P<0·0001) and 1·8 ml (95 % CI 1·1, 2·5; P<0·0001) in AA (Prace difference=0·06), and forced vital capacity (FVC) was higher by 1·3 ml in EA (95 % CI 1·0, 1·6; P<0·0001) and 1·5 ml (95 % CI 0·8, 2·3; P=0·0001) in AA (Prace difference=0·56). Among EA, the 25(OH)D–FVC association was stronger in smokers: per 1 nmol/l higher 25(OH)D, FVC was higher by 1·7 ml (95 % CI 1·1, 2·3) for current smokers and 1·7 ml (95 % CI 1·2, 2·1) for former smokers, compared with 0·8 ml (95 % CI 0·4, 1·2) for never smokers. In summary, the 25(OH)D associations with FEV1 and FVC were positive in both ancestries. In EA, a stronger association was observed for smokers compared with never smokers, which supports the importance of vitamin D in vulnerable populations.

Introduction: Patients with acute atrial fibrillation or flutter (AAFF) are the most common acute arrhythmia cases requiring care in the ED. Our goal was to adapt the existing Canadian Cardiovascular Society (CCS) AF Management Guidelines into an emergency physician-friendly best practices checklist. Methods: We chose to adapt, for use by emergency physicians, existing high-quality clinical practice guidelines (CPG) previously developed by the CCS using the GRADE system. We used the Canadian CAN-IMPLEMENT© process adapted from the ADAPTE Collaboration. We created an Advisory Committee consisting of 14 academic and community emergency physicians, three cardiologists, one PhD methodologist, and two patients. The Advisory Committee communicated by a two-day face-to-face meeting, teleconferences, and email. The checklist was prepared and revised through a process of feedback and discussions through ten iterations until consensus was achieved. We then circulated the draft checklist for comment to approximately 300 emergency medicine and cardiology colleagues whose written feedback was further incorporated into the final approved version. Results: The final CAEP ED AAFF Guidelines are comprised of two algorithms and four sets of checklists, organized by 1) Assessment and Risk Stratification, 2) Rhythm and Rate Control, 3) Long-term Stroke Prevention with the CHADS-65 Algorithm, and 4) Disposition and Follow-up. The guidelines have been endorsed by CAEP and accepted for publication in the Canadian Journal of Emergency Medicine. During the consensus and feedback processes, we addressed a number of issues and concerns. We highlighted the issue that many unstable patients are actually suffering from underlying medical problems rather than a primary arrhythmia. One controversial recommendation is to consider rate control or transesophageal echocardiography guided cardioversion if the duration of symptoms is 24-48 hours and the patient has two or more CHADS-65 criteria. We emphasize the importance of evaluating long-term stroke risk by use of the CHADS-65 algorithm and encourage ED physicians to prescribe anticoagulants where indicated. Conclusion: We have created the CAEP AAFF Best Practices Checklist which we hope will standardize and improve care of AAFF patients in all EDs across Canada. We believe that most of these patients can be managed rapidly and safely with ED rhythm control, early discharge, and appropriate use of anticoagulants.

Radio emission from astrophysical transients allows us to derive calorimetry of kinetic feedback and detailed imaging in ways that are not possible at other wavelengths, and as such it forms an important part of the multi-messenger follow-ups of these events. The field is burgeoning, with a renaissance of interest in accretion, stellar explosions and jetted supernovæ, alongside newer classes of phenomena such as fast radio bursts and tidal disruption events. The purpose of this workshop was to discuss the infrastructure and techniques for detecting, identifying and probing radio transients, with a particular focus on how best to exploit transient alerts from multi-messenger facilities. We examined the type of transient alerts those facilities will broadcast, and methods for following them up, such as rapid-response triggering and shadowing. In break-out groups, participants chose a science question related to a particular radio transient type or class and discussed whether the planned transient strategies and observing techniques on the Square Kilometre Array will be adequate to address the particular question. The classes they chose included fast radio bursts, supernovæ, cataclysmic variable and unknown transients. Any proposed adaptation or suggestion was relayed to a panel of experts for further discussion. The second part of the workshop concentrated on the application of long baseline interferometry for detecting and measuring radio transients.

A fossil assemblage containing molluscs, mammals, insects, ostracodes, and plants has been recovered from a silt-filled depression near Lima, in west-central Illinois. The reversed remanent magnetic signature of the sediments and the temporal ranges of two mammals, Microtus paroperarius and Lasiopodomys deceitensis, constrain the age of the assemblage to between 730,000 and 830,000 yr B.P. The extent of isoleucine epimerization in the molluscan shell is consistent with this age interpretation. The fauna includes at least 43 taxa of beetles from 11 families, 35 nominal species of molluscs, and two genera of ostracodes. The mammals include two shrews, three rodents, and a rabbit. The plant macrofossils (no pollen recovered) include 25 species of seed plants and four kinds of terrestrial or wetland mosses. Most of the plant species identified still occur in the upper Midwest, although a few of the taxa are found mainly to the north of the site. The fauna is characterized by an almost total absence of true aquatic taxa. The association of both boreal and thermophilous faunal and floral elements suggest that summer temperatures were not greatly different from present ones, but cooler, moist areas must have been available to support the boreal elements. Local conditions were probably similar to those now found in northeastern Iowa, where rains blocks, fissures, and joints in carbonate bedrock serve as traps for debris accumulations, provide shade, and are kept cool and moist during the hot summer months by cold-air drainage and groundwater seepage. Summer mean temperature in these microhabitats was probably between 18 and 20°C, similar to temperatures that now occur near the northern hardwood spruce-fir transition in the eastern United States.

The purpose of this note is to present some recently acquired data showing the effects of variations in the open area of slotted liners on the pressures on a twodimensional aerofoil at sonic speed in the 36 inch X 14 inch transonic wind tunnel at the NPL. The basic slotted liners for this tunnel have eleven longitudinal slots, giving an open-area ratio (σ) of 0.091. Other slot openings are obtained by closing appropriate slots with “Sellotape.” Nine values of σ ranging from 0 to 0.091, were used in this investigation. A wall static-pressure orifice, sufficiently far upstream of the model to be unaffected by its presence (3-6 chords), was used as a reference pressure for tunnel speed. The relationship between the Mach number given by this reference pressure and the true tunnel Mach number (M0), at the model location, was obtained by careful calibration.

Closed-form equations for the evaluation of forces on a body in compressible, inviscid and viscous flows are presented. The expressions which are used to calculate lift and drag require only knowledge of the velocity field (and its derivatives) on an arbitrarily chosen contour enclosing the body. Various forms of the force equations are presented, both for two-dimensional and three-dimensional flows. The work is an extension of earlier research by Noca) developed for incompressible flows. The equations are implemented on a number of two-dimensional aerofoil cases and the results show excellent agreement with surface and wake integration approaches.

The present paper continues the work of Zhu et al. The closed-form expressions for the evaluation of forces on a body in compressible, viscous and rotational flow derived in the previous paper have been extended to different forms. The expressions require only a knowledge of the velocity field (and its derivatives) in a finite and arbitrarily chosen region enclosing the body. The equations are implemented on three-dimensional inviscid flows over wings and wing/body combinations. Further implementation on three-dimensional viscous flows over wings has also been investigated.