Nicotine 2,6-dihydroxybenzoate is a nicotine salt that can be used as the nicotine source in tobacco products. X-ray powder diffraction data, unit-cell parameters, and space group for nicotine 2,6-dihydroxybenzoate, C10H15N2⋅C7H5O4, are reported [a = 7.726(8) Å, b = 11.724(3) Å, c = 9.437(1) Å, α = 90°, β = 109.081(3)°, γ = 90°, unit-cell volume V = 802.902 Å3, Z = 2, ρcal = 1.309 g cm−3, and space group P21] at room temperature. All measured lines were indexed and were consistent with the P21 space group.

Two new genera and six new species of trilobites are systematically documented herein: Sinagnostus mirabilis new genus new species, Yanpingia punctata n. gen. n. sp., Illaenus taoyuanensis n. sp., Panderia striolatus n. sp., Nileus yichongqiaoensis n. sp., and Paratiresias peculiaris n. sp. The materials were collected from the Darriwilian (late Middle Ordovician) strata in the Upper Yangtze Region, South China. Also provided is an emended diagnosis of the genus Paratiresias based on the new species Paratiresias peculiaris, which is the oldest known species of this genus with an extremely narrow (sag. and exsag.) preglabellar field. Those Chinese species previously referred to Nanillaenus are reassigned to Illaenus sensu lato. These trilobites add new data for the Darriwilian trilobite macroevolution and show highly endemic to South China and the faunal exchanges between South China and Tarim, Kazakhstan, Alborz, as well as Sibumasu and North China.

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In this paper, we propose and study an almost periodic reaction–diffusion epidemic model in which disease latency, spatial heterogeneity and general seasonal fluctuations are incorporated. The model is given by a spatially nonlocal reaction–diffusion system with a fixed time delay. We first characterise the upper Lyapunov exponent λ* for a class of almost periodic reaction–diffusion equations with a fixed time delay and provide a numerical method to compute it. On this basis, the global threshold dynamics of this model is established in terms of λ* It is shown that the disease-free almost periodic solution is globally attractive if λ* < 0, while the disease is persistent if λ* > 0. By virtue of numerical simulations, we investigate the effects of diffusion rate, incubation period and spatial heterogeneity on disease transmission.

Sexual interaction is an important activity that determines the reproductive schedule of organisms and can ultimately influence the fitness traits of both sexes. Although the influence of sexual interaction on the fitness of females has been extensively determined, little is known about the effects on males, which often have different mating strategies and optimal mating regimes from those of females. To understand how mating regimes (timing and frequency) modulate the fitness in both sexes, we used spider mite (Tetranychus urticae) to investigate the influence of delayed mating and repeated mating on the fitness of male and female. For females, the unmated and the delayed mating females outlived those mated immediately after adult emergence. The repeated mating shortened the lifespan of females that mated at 1-day-old, but not that mated 7-day-old. However, no significant variation in lifespan was observed for males across different mating regimes. We found although delayed mating significantly reduced the daily reproductive rate of the females, there was no significant difference in lifetime reproduction of females across treatments because the delayed mating females increased their reproductive lifespan as a compensation. Our study highlighted that the time and frequency of sexual interaction showed a sex-specific consequence on male and female spider mites, indicating that sexual interaction incurs a higher cost to females which have a much lower optimal mating frequency than males.

Partial differential equations (PDEs) are used with huge success to model phenomena across all scientific and engineering disciplines. However, across an equally wide swath, there exist situations in which PDEs fail to adequately model observed phenomena, or are not the best available model for that purpose. On the other hand, in many situations, nonlocal models that account for interaction occurring at a distance have been shown to more faithfully and effectively model observed phenomena that involve possible singularities and other anomalies. In this article we consider a generic nonlocal model, beginning with a short review of its definition, the properties of its solution, its mathematical analysis and of specific concrete examples. We then provide extensive discussions about numerical methods, including finite element, finite difference and spectral methods, for determining approximate solutions of the nonlocal models considered. In that discussion, we pay particular attention to a special class of nonlocal models that are the most widely studied in the literature, namely those involving fractional derivatives. The article ends with brief considerations of several modelling and algorithmic extensions, which serve to show the wide applicability of nonlocal modelling.

Four ground-state OH transitions were detected in emission, absorption and maser emission in the Southern Parkes Large-Area Survey in Hydroxyl (SPLASH). We re-observed these OH masers with the Australia Telescope Compact Array to obtain positions with high accuracy (~1 arcsec). According to the positions, we categorised these OH masers into different classes, i.e. star formation, evolved stars, supernova remnants and unknown origin. We found one interesting OH maser source (G336.644-0.695) in the pilot region, which has been studied in detail in Qiao et al. (2016a). In this paper, we present the current stage of the ATCA follow-up for SPLASH and discuss the potential future researches derived from the ATCA data.

Porous silicon nitride ceramics are attracting extensive attention due to its high strength and low dielectric loss. However, further strength enhancement at elevated temperatures is hindered by its intergranular phase, forming from sintering additives. This paper describes the fabrication of porous silicon nitride ceramic materials, by using a replacement method of carbothermal nitridation. The initial samples which were obtained from the sintering of mixed powder consisted of 95 wt% Si3N4 and 5 wt% Y2O3. After the removal of the oxide intergranular phase and the infiltration of mixtures of phenolic resins and silica sols, carbothermal nitridation process was carried out at 1550 °C for 2 h under nitrogen. X-ray diffraction and microstructural analysis revealed a complete replacement of oxide intergranular phases by the newly formed Si3N4 intergranular phase. The unmodified ceramic exhibited lower flexural strength at 1400 °C, which was only 50% of the room-temperature strength. Although the modified ceramic attained a slightly lower flexural strength at room temperature after the replacement of intergranular phase, its strength measured at 1400 °C could attain 90% of room-temperature strength.

This investigation addresses the dynamics of annular viscoelastic films flowing down a flexible tube. The fluid viscoelasticity is assumed to be weak in order to obtain approximate explicit expressions for the stresses. Based on Shkadov’s integral boundary layer method (Fluid Dyn., vol. 2(1), 1967, pp. 29–34), a set of nonlinear evolution equations is derived that is valid for flows with moderate Reynolds numbers. The linear stability property of the system is examined by using normal-mode analysis, which is verified by comparing the results with those resulting from the linearization of the full Navier–Stokes equations. The results indicate that the fluid viscoelasticity plays an unstable role in the stability of the annular film flow. The tube flexibility, which includes wall damping and wall tension, plays a dual role. A bifurcation analysis is performed, and the families of steady travelling waves are catalogued. It is found that the stiffness of the tube tends to stimulate the interfacial capillary ripples. The fluid viscoelasticity acts to strengthen the dispersion of the interfacial waves but weakens the interfacial capillary ripples. The spatio-temporal evolutions of the system are also solved numerically. When the tube radius is small enough, tube closure can be observed due to the Plateau–Rayleigh instability. The fluid viscoelasticity acts to promote tube closure while the tube radius is relatively small. However, it plays a role in postponing the closure of the tube with a large radius.

Ground-state OH masers identified in the Southern Parkes Large-Area Survey in Hydroxyl were observed with the Australia Telescope Compact Array to obtain positions with high accuracy (~1 arcsec). We classified these OH masers into evolved star OH maser sites, star formation OH maser sites, supernova remnant OH maser sites, planetary nebula OH maser sites and unknown maser sites using their accurate positions. Evolved star and star formation OH maser sites in the Galactic Centre region (between Galactic longitudes of −5° to +5° and Galactic latitudes of −2° and +2°) were studied in detail to understand their distributions.

A congruent melting compound LiNaV2O6 has been synthesized by high-temperature solution reaction and it has been grown with sizes up to 11 × 6 × 2 mm3 by the top-seeded growth method for the first time. LiNaV2O6 crystallizes in the monoclinic system with space group C2/c, with a = 10.184(2) Å, b = 9.067(2) Å, c = 5.8324(11) Å, β = 108.965(14)°. UV–Vis–NIR diffuse reflectance spectrum of LiNaV2O6 shows that it has a wide transmittance range from 385 to 2500 nm. The ab initio calculations show that the birefringence of LiNaV2O6 is 0.136 at 589.3 nm. Therefore, LiNaV2O6 may be a new birefringent material. Based on the analysis of the relationship between crystal structure and linear optical properties, it is found that the large birefringence is attributed to the particular arrangement of V–O anionic groups.

Recent evidence shows that excess nicotinamide can cause epigenetic changes in developing rats. The aim of the present study was to investigate the effects of maternal nicotinamide supplementation on the fetus. Female rats were randomised into four groups fed a standard chow diet (control group) or diets supplemented with 1 g/kg of nicotinamide (low-dose group), 4 g/kg of nicotinamide (high-dose group) or 4 g/kg of nicotinamide plus 2 g/kg of betaine (betaine group) for 14–16 d before mating and throughout the study. Fetal tissue samples were collected on the 20th day of pregnancy. Compared with the control group, the high-dose group had a higher fetal death rate, and the average fetal body weight was higher in the low-dose group but lower in the high-dose group. Nicotinamide supplementation led to a decrease in placental and fetal hepatic genomic DNA methylation and genomic uracil contents (a factor modifying DNA for diversity) in the placenta and fetal liver and brain, which could be completely or partially prevented by betaine. Moreover, nicotinamide supplementation induced tissue-specific alterations in the mRNA expression of the genes encoding nicotinamide N-methyltransferase, DNA methyltransferase 1, catalase and tumour protein p53 in the placenta and fetal liver. High-dose nicotinamide supplementation increased fetal hepatic α-fetoprotein mRNA level, which was prevented by betaine supplementation. It is concluded that maternal nicotinamide supplementation can induce changes in fetal epigenetic modification and DNA base composition. The present study raises the concern that maternal nicotinamide supplementation may play a role in the development of epigenetic-related diseases in the offspring.

We report results from nearly simultaneous pentachromatic VLBI observations towards a nearby GPS galaxy NGC 1052. The observations at 1.6 and 4.8 GHz with the VSOP, and at 2.3, 8.4, and 15.4 GHz with VLBA, provide linear resolutions of ∼0.1 pc. Convex spectra of a double-sided jet imply that synchrotron emission is obscured through foreground cold dense plasma, in terms of free–free absorption (FFA). We found a central condensation of the plasma which covers about 0.1 and 1 pc of the approaching and receding jets, respectively. A simple model with a geometrically thick plasma torus perpendicular to the jets is established to explain the asymmetric distribution of FFA opacities.

We report very long baseline array (VLBA) observations at 2.3, 8.4, and 15.4 GHz towards nine gigahertz peaked spectrum (GPS) sources. One Seyfert 1 galaxy, one Seyfert 2 galaxy, three radio galaxies, and four quasars were included in our survey. We obtained spatial distributions of the free–free absorption (FFA) opacity with milliarcsecond resolution for all sources. It is found that type 1 (Seyfert 1 and quasars) and type 2 (Seyfert 2 and radio galaxies) sources showed different distributions of the FFA opacities. The type 1 sources tend to show more asymmetric opacity distributions towards a double lobe, while those of the type 2 sources are rather symmetric. Our results imply that the different viewing angle of the jet causes the difference of FFA opacity along the external absorber. This idea supports the unified scheme between quasars and radio galaxies, proposed by Barthel (1989).

Williams syndrome is caused by a gene deletion of chromosome 7. A majority of the cases are sporadic with typical facial appearance, cardiac anomalies, and mental retardation. We report a rare case of Williams syndrome associated with supravalvular aortic stenosis, subvalvular aortic membrane, mitral regurgitation, aortic coarctation, and patent ductus arteriosus. The patient had undergone a single-stage surgical repair with satisfactory results at 5 months of follow-up.

Several divergent sympatry mtDNA lineages have been described in redlip mullet Liza haematocheilus, and this high inter-lineage divergence raises questions about the taxonomic status of L. haematocheilus lineages in the north-western Pacific. In this study, the amplified fragment length polymorphism technique was employed to examine genetic structure of L. haematocheilus and estimate the level of independence of the different mtDNA lineages in the north-western Pacific. A total of 186 bands were amplified from 91 individuals among 8 populations by 4 primer combinations and the percentage of polymorphic bands was 91.74%. The Unweighted Pair Group Method with Arithmetic Mean tree based on Nei genetic distance revealed two clusters (North Clade and South Clade). Molecular variance analysis and pairwise FST supported the separation of north and south populations of L. haematocheilus in the north-western Pacific. The incongruence between nuclear groups and mitochondrial lineages suggests the three distinct lineages do not represent cryptic species and the presence of divergent mitochondrial lineages in the same sample is a result of secondary contact after an extended period of isolation. The Pleistocene isolation and biological characteristics of species may be responsible for the genetic differentiation of L. haematocheilus.