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Insufficient nutrition during the perinatal period causes structural alterations in humans and experimental animals, leading to increased vulnerability to diseases in later life. Japanese quail, Coturnix japonica, in which partial (8–10%) egg white was withdrawn (EwW) from eggs before incubation had lower birth weights than controls (CTs). EwW birds also had reduced hatching rates, smaller glomeruli and lower embryo weight. In EwW embryos, the surface condensate area containing mesenchymal cells was larger, suggesting that delayed but active nephrogenesis takes place. In mature EwW quail, the number of glomeruli in the cortical region (mm2) was significantly lower (CT 34.7±1.4, EwW 21.0±1.2); capillary loops showed focal ballooning, and mesangial areas were distinctly expanded. Immunoreactive cell junction proteins, N-cadherin and podocin, and slit diaphragms were clearly seen. With aging, the mesangial area and glomerular size continued to increase and were significantly larger in EwW quail, suggesting compensatory hypertrophy. Furthermore, apoptosis measured by terminal deoxynucleotidyl transferase-mediated dUTP-biotin nick-end labeling analysis was higher in EwWs than in CTs on embryonic day 15 and postnatal day 4 (D4). Similarly, plasma glucocorticoid (corticosterone) was higher (P<0.01) on D4 in EwW quail. These results suggest that although nephrogenic activity is high in low-nutrition quail during the perinatal period, delayed development and increased apoptosis may result in a lower number of mature nephrons. Damaged or incompletely mature mesangium may trigger glomerular injury, leading in later life to nephrosclerosis. The present study shows that birds serve as a model for ‘fetal programming,’ which appears to have evolved phylogenetically early.
A new approach is proposed to analyze Bremsstrahlung X-rays that are emitted from laser-produced plasmas (LPP) and are measured by a stack type spectrometer. This new method is based on a spectral tomographic reconstruction concept with the variational principle for optimization, without referring to the electron energy distribution of a plasma. This approach is applied to the analysis of some experimental data obtained at a few major laser facilities to demonstrate the applicability of the method. Slope temperatures of X-rays from LPP are determined with a two-temperature model, showing different spectral characteristics of X-rays depending on laser properties used in the experiments.
Establishment of nonindigenous (NI) aquatic plants in the nearshore regions of freshwater ecosystems has resulted in environmental degradation, recreation concerns, economic impacts, and substantial management challenges. To reduce these undesirable effects, NI aquatic plants are often targeted for removal or control by management agencies, but the efficacy of implementation is often not documented or sustained. In this study, we developed a management plan to completely remove all NI plants from Emerald Bay, Lake Tahoe, CA, using only physical control techniques. Management plan priorities were based on previous research and lessons learned, including the need for (1) integrated weed management using multiple physical control techniques, (2) a large initial treatment investment, (3) ongoing early detection and rapid response, (4) detailed ecological monitoring, and (5) a long-term commitment to annual maintenance removal. Application of this management plan resulted in complete removal of all NI aquatic plants from Emerald Bay and substantial cost savings each year after the initial large investment. Annual maintenance removal and monitoring will need to continue as long as NI aquatic plants continue to enter Emerald Bay on boats and currents from other areas of Lake Tahoe.
Seyfert galaxies often have extended emission line regions around their nucleus. We started an observation program of optical tridimensional spectroscopy for circumnuclear regions of nearby Seyfert galaxies to investigate the ionization source of the gas of just vicinity(typically several hundred pc) of nucleus.
A narrow-band imaging observation of the Seyfert galaxy NGC1068 was made in the Fabry-Perot mode of the Kyoto 3D Spectrograph attached to the 188cm telescope of the Okayama Astrophysical Observatory. We observed at wavelengths of Hα, [S ii]λ6716, [S ii]λ6731 and adjacent continua of the respective lines with a “tunable filter”, i.e. a gap-scanning etalon with a spectral resolution of 20 Å.
The Kyoto 3-D Spectrograph was commissioned successfully at the 188-cm telescope of the Okayama Astrophysical Observatory in the spring of 1996. This instrument has four distinct modes (Ohtani et al. 1994): (1) narrow-band imager, which is an ordinary focal-reducer camera; (2) Spectro-NebulaGraph (long-slit spectrograph; Kosugi et al. 1995); (3) imaging Fabry-Perot interferometer, using either of two Fabry-Perot etalons from Queensgate Instruments (a tunable filter with R = 300 and another with R = 7000 for velocity-field observations. Broad-band (400–700 nm) coatings are deposited on both etalons. During observations, the etalon temperature is stabilized within 0.5°C); and (4) integral-field spectrograph of the TIGER-type (Bacon et al. 1995). In this mode, the spectra of 7 × 11 objects can be recorded simultaneously, along with 7 × 2 spectra of the sky 4′ away. The spatial resolution is 1″.3 and the field of view is 9″ × 14″.
We developed a slit-scanning type 3D-spectroscopic system named as Spectronebulagraph (hereafter SNG; Kosugi et al. 1994) at Okayama Astrophysical Observatory. A detailed description about SNG is presented by Ohtani et al. elsewhere in this colloquium. We present here the results of the 3D-spectroscopy of four nearby active galaxies by using SNG.
This nearby (at distance of 5.4 Mpc) Magellanic irregular galaxy has many H II regions in its main body suggesting violent star-formation activity. We performed tridimensional observations of NGC 4449 using SNG in order to obtain detailed kinematic structure and then to investigate the star-formation mechanism of NGC 4449. Hα intensity map, Hα velocity field are shown in figure 1. As is obvious in lower panel of figure 1, no global rotational motion was detected. Most impressive feature of the velocity field is kpc-scale mosaic structure of low velocity and high velocity components. Also, many filamentary components were newly found in 3D-datacube of the SNG observation.
Our Universe provides the grandest arena in which to test General Relativity as a theory of space, time and gravity. It becomes essential to consider both the causal propagation of matter and radiation through space-time and the dynamical evolution of space-time if we are to construct a consistent theoretical framework in which to interpret astronomical observations on the largest observable scales. Einstein himself originally tried to construct a static cosmology but it was soon appreciated that the field equations of General Relativity naturally accommodate dynamical and evolving space-times. Einstein's own static model of a 3-sphere, balancing the gravitational pull of matter against a positive spatial curvature and a cosmological constant was shown to be poised between expansion and collapse and hence unstable to infinitesimal disturbance.
Friedmann and Lemaître showed that Einstein's field equations admit expanding- universe solutions, which have become the basis for modern cosmology, despite Einstein's initial dismissal of the solutions. However persuasive the theoretical models, empirical observations are, of course, necessary to determine the actual dynamics of our observable Universe; the work of Slipher and Hubble in the 1920s  persuaded scientists that in fact our Universe is expanding. The logical consequence of this expansion is that either our Universe was hotter and denser in the past (coming ultimately from a Hot Big Bang) or, perhaps, that energy had to be continually created as the universe expanded (the Steady State model). The discovery of the Cosmic Microwave Background (CMB) radiation by Penzias and Wilson in 1965  convinced most astronomers that the Universe did in fact begin at a Hot Big Bang, a finite time in the past. This hot dense plasma, in thermal equilibrium at early times, also provides a setting for the freezing out of the light atomic nuclei as the universe cools below several million degrees Kelvin , although heavier elements must be formed later in stars.
Group III-Sb compound semiconductors are promising materials for future CMOS circuits. Especially, In1-xGaxSb is considered as a complimentary p-type channel material to n-type In1-xGaxAs MOSFET due to the superior hole transport properties and similar chemical properties in III-Sb’s to those of InGaAs. The heteroepitaxial growth of In1-xGaxSb on Si substrate has significant advantage for volume fabrication of III-V ICs. However large lattice mismatch between InGaSb and Si results in many growth-related defects (micro twins, threading dislocations and antiphase domain boundaries); these defects also act as deep acceptor levels. Accordingly, unintentional doping in InGaSb films causes additional scattering, increase junction leakages and affects the interface properties. In this paper, we studied the correlations between of defects and hole carrier densities in GaSb and strained In1-xGaxSb quantum well layers by using various designs of metamorphic superlattice buffers.
Using a genetic moderation approach, this study examines how an experimental prime of religion impacts self-control in a social context, and whether this effect differs depending on the genotype of an oxytocin receptor gene (OXTR) polymorphism (rs53576). People with different genotypes of OXTR seem to have different genetic orientations toward sociality, which may have consequences for the way they respond to religious cues in the environment. In order to determine whether the influence of religion priming on self-control is socially motivated, we examine whether this effect is stronger for people who have OXTR genotypes that should be linked to greater rather than less social sensitivity (i.e., GG vs. AA/AG genotypes). The results showed that experimentally priming religion increased self-control behaviors for people with GG genotypes more so than people with AA/AG genotypes. Furthermore, this Gene × Religion interaction emerged in a social context, when people were interacting face to face with another person. This research integrates genetic moderation and social psychological approaches to address a novel question about religion's influence on self-control behavior, which has implications for coping with distress and psychopathology. These findings also highlight the importance of the social context for understanding genetic moderation of psychological effects.
The shear deformations of pillared-graphene nanostructures are investigated using molecular dynamics simulation. Slight anisotropy regarding the direction of a shear load is detected. Changing the loading area in graphene and the radius of a single-walled carbon nanotube (SWNT) as a pillar, the deformations near the joints of graphene and a SWNT are examined in detail. It is concluded the anisotropy of the shear deformation of the nanostructure is due to the atomic structures at the joints of graphene and a SWNT as a pillar, and the out-of-plane deformations of graphene near the joints dominantly affect the overall shear deformation of the nanostructure.
In this study, aluminized, boronized, chromized and siliconized gray cast iron plate specimens were prepared, and their microstructures and tribological properties were investigated. The surfaces of the aluminized, boronized, chromized and siliconized specimens mainly consisted of FeAl, Fe2B, (Cr, Fe)23C6 and FeSi phases, respectively. Also, the surface of the boronized specimen exhibited the highest microvickers hardness of all the specimens. The aluminized, boronized and chromized specimens exhibited friction coefficients as low as the non-coated specimens when sliding against AISI 52100 steel ball specimens in poly-alpha-olefin. In addition, the boronized and chromized specimens exhibited much higher wear resistance than the non-coated specimens.