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Little research has assessed serum 25-hydroxyvitamin D (25(OH)D) concentration and its predictors in western dwelling South Asians in a relatively large sample size. This observational, cross-sectional analysis assessed baseline prevalence of 25(OH)D deficiency in UK dwelling South Asians (aged 40-69 years, 2006-2010) from the UK Biobank cohort. Serum 25(OH)D measurements were undertaken using the DiaSorin Liaison XL assay. Of n 6433 South Asians with a 25(OH)D measurement, using commonly used cut-off thresholds, 55% (n 3538) had 25(OH)D <25 nmol/L (severe deficiency) and 92% (n 5918) had 25(OH)D <50 nmol/L (insufficiency). Twenty per cent (n 1287) had 25(OH)D concentration <15 nmol/L (very severe deficiency). When n 824 participants with undetectable (<10 nmol/L) 25(OH)D measurements were included (total n 7257), 29% (n 2105) had 25(OH)D <15 nmol/L, 60% (n 4354) had 25(OH)D <25 nmol/L and 93% (n 6749) had 25(OH)D < 50 nmol/L. Logistic regression predictors of 25(OH)D <25 nmol/L included the following characteristics: being male; Pakistani; higher body mass index; 40-59 years old; never consuming oily fish; summer sun exposure < 5 hours per day, not using a vitamin D containing supplement, measurement in winter or spring and vegetarianism. In terms of region, median 25(OH)D concentration was 19-20 nmol/L in Scotland, Northern England, the Midlands and Wales. Across Southern England and London it was slightly higher at 24-25 nmol/L. Our analyses suggest the need for increased awareness of vitamin D deficiency in South Asians as well as urgent public health interventions to prevent and treat vitamin D deficiency in this group.
The stellar disc of the Milky Way exhibits clear departures from planarity, the most conspicuous manifestation being the Galactic Warp but also includes an apparent corrugation pattern in number counts around 15kpc from the Galactic centre, a wave like pattern in the vertical velocities of stars as a function of guiding radius, asymmetries about the midplane in both number counts and bulk motions, and phase spirals in the z–vz projection of the local stellar distribution function. We discuss the physics of these phenomena and, in particular, suggest a possible avenue for inferring the vertical force in the Solar Neighbourhood from phase spirals. We apply Dynamic Mode Decomposition, a technique widely used in the realm of fluid mechanics, to simulations of disc galaxy simulations. This method appears to be particularly well-suited to the study of nonlinear processes such as the coupling of warps and spirals, first discussed by Masset and Tagger.
Isoconcentration surfaces are commonly used to delineate phases in atom probe datasets. These surfaces then provide the spatial and compositional reference for proximity histograms, the number density of particles, and the volume fraction of particles within a multiphase system. This paper discusses the influence of the isoconcentration surface selection value on these quantitative outputs, using a simple oxide dispersive strengthened alloy, Fe91Ni8Zr1, as the case system. Zirconium reacted with intrinsic oxygen impurities in a consolidated ball-milled powder to precipitate nanoscale zirconia particles. The zirconia particles were identified by varying the Zr-isoconcentration values as well as by the maximum separation data mining method. The associated outputs mentioned above are elaborated upon in reference to the variation in this Zr isosurface value. Considering the dataset as a whole, a 10.5 at.% Zr isosurface provided a compositional inflection point for Zr between the particles and matrix on the proximity histogram; however, this value was unable to delineate all of the secondary oxide particles identified using the maximum separation method. Consequently, variations in the number density and volume fraction were observed as the Zr isovalue was changed to capture these particles resulting in a loss of the compositional accuracy. This highlighted the need for particle-by-particle analysis.
Vitamin D deficiency (serum 25-hydroxyvitamin D<25 nmol/l) is extremely common in Western-dwelling South Asians but evidence regarding vitamin D supplement usage in this group is very limited. This work identifies demographic, dietary and lifestyle predictors associated with vitamin D supplement use.
Cross-sectional analysis of baseline vitamin D supplement use data.
UK Biobank cohort.
In total, 8024 South Asians (Bangladeshi, Indian, Pakistani), aged 40–69 years.
Twenty-three per cent of men and 39 % of women (P<0·001) (22 % of Bangladeshis, 32 % of Indians, 25 % of Pakistanis (P<0·001)) took a vitamin-D-containing supplement. Median vitamin D intakes from diet were low at 1·0–3·0 µg/d, being highest in Bangladeshis and lowest in Indians (P<0·001). Logistic regression modelling showed that females had a higher odds of vitamin D supplement use than males (OR=2·02; 95 % CI 1·79, 2·28). A lower supplement usage was seen in younger persons (40–60 years v. >60 years: OR=0·75; 95 % CI 0·65, 0·86) and in those living outside Greater London (OR=0·53 to 0·77), with borderline trends for a lower BMI, higher oily fish intake and higher household income associated with increased odds of vitamin D supplement use.
Vitamin D supplements were not used by most South Asians and intakes from diet alone are likely to be insufficient to maintain adequate vitamin D status. Public health strategies are now urgently required to promote the use of vitamin D supplements in these specific UK South Asian subgroups.
The dwarf galaxies in the Local Group (LG) reveal a surprising amount of spatial structuring. In particular, almost all non-satellite dwarfs belong to one of two planes that show a very pronounced symmetry. In order to determine if these structures in the LG are dynamically stable or, alternatively, if they only represent transient alignments, proper motion measurements of these galaxies are required. A viable method to derive proper motions is offered by VLBI studies of 22-GHz water (and 6.7-GHz methanol) maser lines in star-forming regions.
In 2016, in the framework of the Early Science Program of the Sardinia Radio Telescope (SRT), we have conducted an extensive observational campaign to map the entire optical body of all the LG dwarf galaxies that belong to the two planes, at C and K band, in a search for methanol and water maser emission.
Here, we outline the project and present its first results on 3 targets, NGC 6822, IC 1613, and WLM. While no luminous maser emission has been detected in these galaxies, a number of interesting weaker detections has been obtained, associated with particularly active star forming regions. In addition, we have produced deep radio continuum maps for these galaxies, aimed at investigating their star forming activity and providing an improved assessment of star formation rates in these galaxies.
Previous research on agriculture in the American Southwest focuses overwhelmingly on archaeological survey methods to discern surface agricultural features, which, in combination with climatological, geological, and geographical variables, are used to create models about agricultural productivity in the past. However, with few exceptions, the role of floodplain irrigation and floodwater farming in ancestral Pueblo agriculture is generally downplayed in scholarly discourse. Using a variety of methods, including Unmanned Aerial Vehicles (UAV), satellite imagery, pedestrian survey, and supervised classification of remotely sensed imagery, we examine this issue through a consideration of how ancestral Ohkay Owingeh (Tewa) people solved the challenges of arid land farming in the lower Rio Chama watershed of New Mexico during the Classic period (A.D. 1350–1598). Based on acreage estimates, our results indicate that runoff and rainwater fields in terrace environments would have been insufficient to supply the nutritional needs of an ancestral Tewa population exceeding 10,000 individuals. Based on these observations, we present a case for the substantial role of subsistence agriculture in the floodplain of the Rio Chama and its associated tributaries.
Virkisjökull is a rapidly retreating outlet glacier draining the western flanks of Öræfajökull in SE Iceland. Since 2011 there have been continuous measurements of flow in the proglacial meltwater channel and regular campaigns to sample stable isotopes δ2H and δ18O from the river, ice, moraine springs and groundwater. The stable isotopes provide reliable end members for glacial ice and shallow groundwater. Analysis of data from 2011 to 2014 indicates that although ice and snowmelt dominate summer riverflow (mean 5.3–7.9 m3 s−1), significant flow is also observed in winter (mean 1.6–2.4 m3 s−1) due primarily to ongoing glacier icemelt. The stable isotope data demonstrate that the influence of groundwater discharge from moraines and the sandur aquifer increases during winter and forms a small (15–20%) consistent source of baseflow to the river. The similarity of hydrological response across seasons reflects a highly efficient glacial drainage system, which makes use of a series of permanent englacial channels within active and buried ice throughout the year. The study has shown that the development of an efficient year round drainage network within the lower part of the glacier has been coincident with the stagnation and subsequent rapid retreat of the glacier.
The formation of a metastable Cu–Ta solid solution in a mechanically alloyed Cu–10 at.%Ta alloy and its subsequent decomposition during annealing was investigated by atom probe tomography. During annealing, the as-milled Cu-rich alloy undergoes phase separation; Ta atoms diffuse out of the Cu lattice to form Ta clusters and particles along grain boundaries and within the Cu grains. The role of the Ta clusters and the nature of the solid solution as a potential strengthening mechanism for these alloys are discussed.
Traditional electron microscopy techniques such as bright-field imaging provide poor contrast for organic films and identification of structures in amorphous material can be problematic, particularly in high-performance organic solar cells. By combining energy-filtered corrected transmission electron microscopy, together with electron energy loss and X-ray energy-dispersive hyperspectral imaging, we have imaged PTB7/PC61BM blended polymer optical photovoltaic films, and were able to identify domains ranging in size from several hundred nanometers to several nanometers in extent. This work verifies that microstructural domains exist in bulk heterojunctions in PTB7/PC61BM polymeric solar cells at multiple length scales and expands our understanding of optimal device performance providing insight for the design of even higher performance cells.
Nickel-yttrium nanocrystalline alloys with an as-milled grain size of approximately 6.5 nm were synthesized using high-energy cryogenic mechanical alloying. The microstructural changes due to annealing were characterized using x-ray line broadening, microhardness, focused ion beam channeling contrast imaging, and transmission electron microscopy. Experiments demonstrated that increasing yttrium content led to stabilization of the nanocrystalline grain size at elevated homologous annealing temperatures. Additionally, it was found that inadvertent contamination with nitrogen during the milling process caused the formation of yttrium nitride (YN) precipitates, which, in turn, resulted in an additional nonlinear hardening effect beyond the expected hardening due to grain-size reduction. Results reveal that kinetic pinning by YN particles is effective in retaining a nanostructure to relatively high temperatures.
The future of centimetre and metre-wave astronomy lies with the Square Kilometre Array (SKA), a telescope under development by a consortium of 17 countries that will be 50 times more sensitive than any existing radio facility. Most of the key science for the SKA will be addressed through large-area imaging of the Universe at frequencies from a few hundred MHz to a few GHz. The Australian SKA Pathfinder (ASKAP) is a technology demonstrator aimed in the mid-frequency range, and achieves instantaneous wide-area imaging through the development and deployment of phased-array feed systems on parabolic reflectors. The large field-of-view makes ASKAP an unprecedented synoptic telescope that will make substantial advances in SKA key science. ASKAP will be located at the Murchison Radio Observatory in inland Western Australia, one of the most radio-quiet locations on the Earth and one of two sites selected by the international community as a potential location for the SKA. In this paper, we outline an ambitious science program for ASKAP, examining key science such as understanding the evolution, formation and population of galaxies including our own, understanding the magnetic Universe, revealing the transient radio sky and searching for gravitational waves.
Attempting to distangle density and kinetic temperature of the star forming molecular gas in the central regions of galaxies, we have embarked on a project involving sensitive measurements of a variety of formaldehyde (H2CO) and ammonia (NH3) transitions. Preliminary results, based on observations from the Green Bank Telescope (GBT) and the Very Large Array (VLA) are summarized and an outline for the entire project is given.
Economic reforms introduced by the Bourbon Monarchy after A.D. 1750 ushered in an Hispanic social formation in the northern Rio Grande identified as Vecino. Aspects of Vecino gendered economy are examined through a detailed analysis of five ceramic assemblages from the Chama and Taos Valleys of New Mexico. Geochemical (NAA) and stylistic clues identify the ethnic identities of producers and their relationships to Vecino consumers. Evidence for ceramic production by Vecino women during the nineteenth century is evaluated on the basis of detailed paste analysis of plain and micaceous ceramics as well as the occurrence of pottery-producing tools and clay-cleaning debris. Analytical results reveal that Jicarilla women dominated the production of micaceous cook ware to supply Vecino kitchens. Implications for understanding Vecino economics and the constitution of female-based systems of economic value are considered.