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The search for life in the Universe is a fundamental problem of astrobiology and modern science. The current progress in the detection of terrestrial-type exoplanets has opened a new avenue in the characterization of exoplanetary atmospheres and in the search for biosignatures of life with the upcoming ground-based and space missions. To specify the conditions favourable for the origin, development and sustainment of life as we know it in other worlds, we need to understand the nature of global (astrospheric), and local (atmospheric and surface) environments of exoplanets in the habitable zones (HZs) around G-K-M dwarf stars including our young Sun. Global environment is formed by propagated disturbances from the planet-hosting stars in the form of stellar flares, coronal mass ejections, energetic particles and winds collectively known as astrospheric space weather. Its characterization will help in understanding how an exoplanetary ecosystem interacts with its host star, as well as in the specification of the physical, chemical and biochemical conditions that can create favourable and/or detrimental conditions for planetary climate and habitability along with evolution of planetary internal dynamics over geological timescales. A key linkage of (astro)physical, chemical and geological processes can only be understood in the framework of interdisciplinary studies with the incorporation of progress in heliophysics, astrophysics, planetary and Earth sciences. The assessment of the impacts of host stars on the climate and habitability of terrestrial (exo)planets will significantly expand the current definition of the HZ to the biogenic zone and provide new observational strategies for searching for signatures of life. The major goal of this paper is to describe and discuss the current status and recent progress in this interdisciplinary field in light of presentations and discussions during the NASA Nexus for Exoplanetary System Science funded workshop ‘Exoplanetary Space Weather, Climate and Habitability’ and to provide a new roadmap for the future development of the emerging field of exoplanetary science and astrobiology.
Section 4 of the FM14 focus on the outreach action and advocacy in the context of IAUs 2020-2030 Strategic Plan. This paper also contains supplementary materials that point to contributed talks and poster presentations that can be found online.
To assess the diagnostic role of mean platelet volume in tonsillitis with and without peritonsillar abscess.
Methods
Mean platelet volume and other laboratory data were retrospectively investigated.
Results
Mean platelet volume was significantly lower in the tonsillitis group (7.8 per cent ± 0.7 per cent) than in the control group (8.7 per cent ± 0.6 per cent; p < 0.0001), and it was significantly lower in the abscess group (7.5 per cent ± 0.6 per cent) than in the no abscess group (8.0 per cent ± 0.7 per cent; p = 0.0277). White blood cell counts and C-reactive protein levels were not significantly different between patients with an abscess and those without. The mean platelet volume cut-off values for the diagnosis of tonsillitis and peritonsillar abscess were 7.95 fl and 7.75 fl, respectively.
Conclusion
Our results suggest that a decreased mean platelet volume is associated with the development and severity of tonsillitis. This finding provides useful diagnostic information for physicians treating patients with tonsillitis.
NUMO and JAEA have been conducting a joint research since FY2011, which is aimed
to enhance the methodology of repository design and performance assessment in
preliminary investigation stage for the deep geological disposal of high-level
radioactive waste. As a part of this joint research, we have been developing
glass dissolution models which include various processes derived from
glass-overpack-bentonite buffer interaction, considering the precipitation of
Fe-silicates associated with steel overpack corrosion, and Si transport through
altered layer of glass. The objective of this modeling work is to show
comprehensively the lifetime of the vitrified waste due to glass matrix
dissolution timescales through sensitivity analysis, and to identify the
feature/process that most strongly influences the lifetime, and to identify
future R&D issues that would help to improve the nuclide transport
analysis with confidential value and the safety case in future. The sensitivity
analysis suggested that the duration of the glass dissolution might be predicted
in the ranges from 3.8×103 to 1.9×105
years. Also, the results indicated that the precipitation of
Fe–silicate has the strongest influence on the long-team behavior of
vitrified waste.
Three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging has been used to detect alterations in the composition of inner-ear fluid. This study investigated the association between hearing level and the signal intensity of pre- and post-contrast three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging in patients with sudden-onset sensorineural hearing loss.
Method:
Three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging was performed in 18 patients with sudden-onset sensorineural hearing loss: 12 patients with mild-to-moderate sensorineural hearing loss (baseline hearing levels of 60 dB or less) and 6 patients with severe-to-profound sensorineural hearing loss (baseline hearing levels of more than 60 dB).
Results:
High-intensity signals in the inner ear were observed in two of the six patients (33 per cent) with severe-to-profound sensorineural hearing loss, but not in those with mild-to-moderate sensorineural hearing loss (mid-p test, p = 0.049). These signals were observed on magnetic resonance imaging scans 6 or 18 days after sensorineural hearing loss onset.
Conclusion:
The results indicate that three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging is not a useful tool for detecting inner-ear abnormalities in patients with mild sensorineural hearing loss.
A seroprevalence survey on measles, mumps, rubella and varicella was conducted on healthcare workers (HCWs) at Shimane University Hospital, Japan utilizing an enzyme immunoassay. Of 1811 HCWs tested, 91·8% were seropositive to measles, 92·1% to mumps, 89·5% to rubella and 96·3% to varicella. Sex-related differences in seroprevalence were found in rubella (males vs. females: 84·7 vs. 92·2%, P < 0·001). Moreover, males aged 30–39 years were most susceptible to rubella (22·4%), which may be attributed to the design of childhood immunization programmes in Japan. Individuals aged ⩽29 years were more susceptible to measles (14·3%) and mumps (10·9%), compared to other age groups. There were no significant sex- and age-related differences in varicella seroprevalence. The physician occupational group was more susceptible to rubella, but no significant occupational-related difference was observed in the other diseases. Susceptible subjects, with negative or equivocal serological results were given a vaccine which induced seroconversion in most vaccinees. Seroconversion occurred more frequently in the equivocal group than in the negative group. These findings provide a new insight for the seroprevalence survey of vaccine-preventable diseases in Japanese HCWs with special reference to vaccine efficacy.
The effects of sucrose supplementation on nitrogen kinetics and energy metabolism were examined in sheep fed lucerne hay cubes using a 15N isotope dilution method and balance and respiration trials in Tsukuba, Japan in 1988. Sheep were fed lucerne hay cubes (1183 g DM/day), with or without 204 g/day sucrose, at 2 h intervals from continuous feeders. Supplementation with sucrose decreased urinary N excretion (P < 0·01), resulting in an increase in N retention from – 1·1 to + 2·0 g N/day (P < 0·01). Supplementation with sucrose resulted in no change in faeces and methane energy, a decrease in urinary energy (P < 0·01) and an increase in heat production and energy balance (P < 0·01). Sucrose supplementation also resulted in lower rumen ammonia (P < 0·05) and plasma urea concentrations (P < 0·05) and reduced urinary urea excretion (P < 0·01). The fermentation of sucrose in the rumen resulted in a decrease in rumen pH (P < 0·01) and in the acetate: propionate ratio (P < 0·05). Sucrose supplementation increased the proportion of urea transferred to the rumen (P < 0·05), non-ammonia N (NAN) concentration in the rumen (P < 0·001) and NAN flow from the rumen to the lower digestive tract (P < 0·001). Urinary allantoin excretion rate increased with sucrose supplementation (P < 0·05). The plasma glucose concentration was unchanged but plasma insulin concentration was increased with sucrose supplementation (P < 0·05). The influence of energy-rich supplements, such as sucrose, on N kinetics and the mechanism of the increase in N retention with sucrose supplementation are discussed.
A fast-charging, discharge-switch-free Blumlein pulse forming line has been developed for high-voltage pulsed power generation. In the BL, a saturable charging inductor (CI) of amorphous metallic core is utilized and, as a result, fast-charging (charging time ≈220 ns) is obtained with a reduced prepulse. In addition, by using CI as a step-up transformer, the impedance of the output pulse can be converted to 4Z, Z, Z/4. By using the BL with a Marx generator of 300 kV and 1.1 kJ, an output of —580 kV at 24 kA and a pulse length of 60 ns are obtained, with a current rise time of less than 16 ns. The energy transfer efficiency of the line (output pulse energy/charging energy of a pulse forming line) is evaluated to be more than 92%.
We present an overview of recent astrometric results with VERA. Since 2004, we have been conducting astrometry of tens of Galactic maser sources with VERA, and recently obtained trigonometric parallaxes for several sources, with distances ranging from 180 pc to 5.3 kpc. In this paper, we briefly summarize the results for Galactic star-forming regions, including S269, Orion-KL, NGC 1333, ρ-oph, NGC 281 and others.
VERA aims at astrometric observations using phase referencing VLBI techniques, whose goal is a 10 micro arc-second accuracy for annual parallax measurements. VERA has four 20-m diameter VLBI radio telescopes in Japanese archipelago with the maximum baseline length of 2,300 km. They have the two-beam observing system, which makes simultaneous observations of two objects possible. This leads to very accurate phase referencing VLBI observations. An important science goal is to make a 3-dimensional map of the Galaxy and reveal its dynamics. In order to achieve this, VERA has the 22GHz and 43GHz bands for H2O and SiO maser objects, respectively. Maser objects are compact and suitable for astrometry observations. VERA's construction was started in 2000 and the array became operational in 2004. We have already measured annual parallaxes and proper motions of some galactic objects. In the future, VERA will collaborate with Korean and Chinese VLBI stations.
Parallax measurements of the Galactic Mira variables with VERA have started since 2004 to establish their Period-Luminosity (PL) relationship in the Galaxy. Multi-epoch VLBI observations of a semiregular variable S Crt yielded an accurate parallax of 2.27±0.14 mas corresponding to the distance of 441+29−24 pc. In addition to the distance, we obtained physical properties of S Crt. Temperature of the photosphere was found to be ~3000 K by fitting the infrared spectrum with a blackbody radiation. The stellar radius was obtained based on the distance, apparent magnitude, and the temperature. Internal proper motions of circularly-arranged maser spots in S Crt were detected for the first time. Observations of the other Mira variables, such as R UMa, SY Scl, AP Lyn, and WX Psc are in progress.
We present the results of a mm wavelength methanol maser survey towards massive star forming regions. We have carried out Class II methanol maser observations at 86.6 GHz, 86.9 GHz and 107.0 GHz, simultaneously, using the Nobeyama 45 m telescope. We selected 108 6.7 GHz methanol maser sources with declinations above −25 degrees and fluxes above 20 Jy. The detection limit of maser observations was ~3 Jy. Of the 93 sources surveyed so far, we detected methanol emission in 25 sources (27%) and “maser” emission in nine sources (10%), of which thre “maser” sources are new detections. The detection rate for maser emission is about half that of a survey of the southern sky (Caswell et al. 2000). There is a correlation between the maser flux of 107 GHz and 6.7 GHz/12 GHz emission, but no correlation with the “thermal” (non maser) emission. From results of other molecular line observations, we found that the sources with methanol emission show higher gas temperatures and twice the detection rate of SiO emission. This may suggest that dust evaporation and destruction by shock are responsible for the high abundance of methanol molecules, one of the required physical conditions for maser emission.