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Cotton producers need residual herbicides that can safely and practically be applied postemergence (POST). Herbicide-coated fertilizers could allow for simultaneous application of residual herbicides and a bulk fertilizer blend. Therefore, a study was conducted in 2022 and 2023 in Fayetteville, AR, to evaluate cotton tolerance to 12 herbicide treatments coated onto a fertilizer blend and applied over cotton. Herbicides and rates evaluated included: diuron at 840 g ai ha-1, florpyrauxifen-benzyl at 29 g ai ha-1, flumioxazin at 105 g ai ha-1, flumioxazin plus pyroxasulfone at 70 + 90 g ai ha-1, fluridone at 168 g ai ha-1, fluometuron at 840 g ai ha-1, fomesafen at 280 g ai ha-1, pyroxasulfone at 128 g ai ha-1, saflufenacil at 66 g ai ha-1, saflufenacil plus dimethenamid-P at 25 + 219 g ai ha-1, saflufenacil plus pyroxasulfone at 44 + 91 g ai ha-1, and S-metolachlor at 1388 g ai ha-1. In both years, fluridone, fluometuron, diuron, and S-metolachlor caused less than 10% injury at 7 d after treatment (DAT). Higher injury levels were observed in 2022 (19 to 30%) compared to 2023 (4 to 12%) for flumioxazin, fomesafen, saflufenacil, saflufenacil plus dimethenamid-P, and saflufenacil plus pyroxasulfone. The elevated injury in one of two years was attributed to the presence of dew when the herbicide-coated fertilizer was applied. The initial injury was transient, as the cotton generally had recovered by 28 DAT for all herbicides. No differences in seed cotton yield or groundcover among the herbicide treatments occurred either year. These results highlight the potential of using several POST-applied, residual herbicides coated on fertilizer that are not currently registered for over-the-top use in cotton.
The computation of intercorrelation matrices involving large numbers of variables and the subsequent factoring of these matrices present a formidable task. A method for estimating factor loadings without computing the intercorrelation matrix is developed. The estimation procedure is derived from a theoretical model which is shown to be a special case of the multiple-group centroid method of factoring. Empirical checks have indicated that the model, even though it makes some stringent assumptions, can be applied to a variety of variables found in psychological factoring problems. It has been found to be particularly useful in factoring test items.
Motor neuron disease (MND) is a progressive, fatal, neurodegenerative condition that affects motor neurons in the brain and spinal cord, resulting in loss of the ability to move, speak, swallow and breathe. Acceptance and commitment therapy (ACT) is an acceptance-based behavioural therapy that may be particularly beneficial for people living with MND (plwMND). This qualitative study aimed to explore plwMND’s experiences of receiving adapted ACT, tailored to their specific needs, and therapists’ experiences of delivering it.
Method:
Semi-structured qualitative interviews were conducted with plwMND who had received up to eight 1:1 sessions of adapted ACT and therapists who had delivered it within an uncontrolled feasibility study. Interviews explored experiences of ACT and how it could be optimised for plwMND. Interviews were audio recorded, transcribed and analysed using framework analysis.
Results:
Participants were 14 plwMND and 11 therapists. Data were coded into four over-arching themes: (i) an appropriate tool to navigate the disease course; (ii) the value of therapy outweighing the challenges; (iii) relevance to the individual; and (iv) involving others. These themes highlighted that ACT was perceived to be acceptable by plwMND and therapists, and many participants reported or anticipated beneficial outcomes in the future, despite some therapeutic challenges. They also highlighted how individual factors can influence experiences of ACT, and the potential benefit of involving others in therapy.
Conclusions:
Qualitative data supported the acceptability of ACT for plwMND. Future research and clinical practice should address expectations and personal relevance of ACT to optimise its delivery to plwMND.
Key learning aims
(1) To understand the views of people living with motor neuron disease (plwMND) and therapists on acceptance and commitment therapy (ACT) for people living with this condition.
(2) To understand the facilitators of and barriers to ACT for plwMND.
(3) To learn whether ACT that has been tailored to meet the specific needs of plwMND needs to be further adapted to potentially increase its acceptability to this population.
The physical health comorbidities and premature mortality experienced by people with mental illness has led to an increase in exercise services embedded as part of standard care in hospital-based mental health services. Despite the increase in access to exercise services for people experiencing mental illness, there is currently a lack of guidelines on the assessment and triage of patients into exercise therapy.
Aims
To develop guidelines for the pre-exercise screening and health assessment of patients engaged with exercise services in hospital-based mental healthcare and to establish an exercise therapy triage framework for use in hospital-based mental healthcare.
Method
A Delphi technique consisting of two online surveys and two rounds of focus group discussions was used to gain consensus from a multidisciplinary panel of experts.
Results
Consensus was reached on aspects of pre-exercise health screening, health domain assessment, assessment tools representing high-value clinical assessment, and the creation and proposed utilisation of an exercise therapy triage framework within exercise therapy.
Conclusions
This study is the first of its kind to provide guidance on the implementation of exercise therapy within Australian hospital-based mental healthcare. The results provide recommendations for appropriate health assessment and screening of patients in exercise therapy, and provide guidance on the implementation and triage of patients into exercise therapy via a stepped framework to determine (a) the timeliness of exercise therapy required and (b) the level of support required in the delivery of their exercise therapy.
Lynchets, often the defining component of historic agricultural landscapes in northern Europe, are generally associated with soft-limestone geologies and are particularly well developed on loess-mantled landscapes. To understand their formation and chronology, the authors present their geoarchaeological analyses of lynchet soils and loess deposits at Blick Mead and Charlton Forest in southern England, and Sint Martens-Voeren in Belgium. The lynchets date from the late prehistoric to the medieval periods and were constructed by plough action at the English sites, and by both cut-and-fill and ploughing in Belgium. This has resulted in the preservation of highly fertile loessic soils across chalk slopes, lost elsewhere. Although each example is associated with local/regional agricultural histories, the lynchets’ effective soil-retention capacities allowed them to survive as important heritage features with environmental benefits over millennia.
Very little is known about the mental health of the adult population of Ukraine following Russia’s full-scale invasion in February 2022. In this study, we estimated the prevalence of seven mental health disorders, the proportion of adults screening positive for any disorder, and the sociodemographic factors associated with meeting requirements for each and any disorder.
Methods
A non-probability quota sample (N = 2,050) of adults living in Ukraine in September 2023 was collected online. Participants completed self-report questionnaires of the seven mental health disorders. Logistic regression was used to determine the predictors of the different disorders.
Results
Prevalence estimates ranged from 1.5% (cannabis use disorder) to 15.2% (generalized anxiety disorder), and 36.3% screened positive for any of the seven disorders. Females were significantly more likely than males (39.0% vs. 33.8%) to screen positive for any disorder. Disruption to life due to Russia’s 2014 invasion of Ukraine, greater financial worries, and having fewer positive childhood experiences were consistent risk factors for different mental health disorders and for any or multiple disorders.
Conclusion
Our findings show that approximately one in three adults living in Ukraine report problems consistent with meeting diagnostic requirements for a mental health disorder 18 months after Russia’s full-scale invasion. Ukraine’s mental healthcare system has been severely compromised by the loss of infrastructure and human capital due to the war. These findings may help to identify those most vulnerable so that limited resources can be used most effectively.
Many foodborne illness outbreaks originate in food service establishments. We tested two behavioural interventions designed to improve the duration and quality of handwashing. We ran a three-armed parallel trial in a laboratory kitchen, from 7 March to 27 May 2022. Participants were n = 195 workers who handle food. We randomly allocated participants to three groups: Timer – tap-mounted timer that counted seconds while participants washed their hands; Precommitment – agreed to five statements on good hand hygiene before attending the kitchen; and Control. Participants completed a food preparation task under time pressure. Cameras focused on the sink captured handwashing. Outcome measures were number of times participants washed their hands; number of times they washed their hands using soap; number of times they washed using soap and washed the backs of their hands; and mean duration of handwashing attempts using soap. Participants in Timer washed their hands for 1.9 s longer on average than Control (β = 2.20, 95% CI = 0.34-4.06, p = 0.021). Participants in Precommitment washed their hands for 2.5 s longer on average than Control (β = 2.30, 95% CI = 0.33-4.27, p = 0.022). We found no statistically significant differences on any other outcome measure.
COVID-19 had the potential to dramatically increase public support for welfare. It was a time of apparent increased solidarity, of apparently deserving claimants, and of increasingly widespread exposure to the benefits system. However, there are also reasons to expect the opposite effect: an increase in financial strain fostering austerity and self-interest, and thermostatic responses to increasing welfare generosity. In this paper, we investigate the effects of the pandemic on attitudes towards working-age unemployment benefits in the UK using a unique combination of data sources: (i) temporally fine-grained data on attitudinal change over the course of the pandemic; and (ii) a novel nationally representative survey contrasting attitudes towards pandemic-era and pre-pandemic claimants (including analysis of free-text responses). Our results show that the pandemic prompted little change in UK welfare attitudes. However, we also find that COVID-era unemployment claimants were perceived as substantially more deserving than those claiming prior to the pandemic. This contrast suggests a strong degree of ‘COVID exceptionalism’ – with COVID claimants seen as categorically different from conventional claimants, muting the effect of the pandemic on welfare attitudes overall.
3D printing is a widely used technology for automating the fabrication of prototypes. The benefits are wide reaching, and include low required expertise, accurate geometric form and the processibility of many materials. However, production of certain forms – especially large forms – can be slow. From review of the sub-systems, the hotend is commonly found to be the limiting factor. To improve this, a modified nozzle design is considered that incorporates a flat copper plate within the flow stream. Analytical simulation was used to guide this design before experimental methods validated the modifications. The maximum volumetric rate for the standard hotend nozzle is 14 mm3/s. The best performing modified nozzle increased the maximum volumetric flow rate to 26 mm3/s – an 86% increase. A series of popular parts were further considered, demonstrating a maximum ∼48% fabrication time reduction, and a mean of ∼23%. This enables 3D printed prototypes to be made more efficiently – both with regards to the design cycle and energy use – and allows designers to use the technology more rapidly than previously possible. By extension, this improves the efficiency of the design process.
The International Design Engineering Annual (IDEA) Challenge is a virtually hosted hackathon for Engineering Design researchers with aims of: i) generating open access datasets; ii) fostering community between researchers; and, iii) applying great design minds to develop solutions to real design problems. This paper presents the 2022 IDEA challenge and elements of the captured dataset with the aim of providing insights into prototyping behaviours at virtually hosted hackathons, comparing it with the 2021 challenge dataset and providing reflections and learnings from two years of running the challenge. The dataset is shown to provide valuable insights into how designers spend their time at hackathon events and how, why and when prototypes are used during their design processes. The dataset also corroborates the findings from the 2021 dataset, demonstrating the complementarity of physical and sketch prototypes. With this paper, we also invite the wider community to contribute to the IDEA Challenge in future years, either as participants or in using the platform to run their own design studies.
Recent work has demonstrated that human body odour alters with changing emotional state and that emotionally laden odours can affect the physiology and behaviour of people exposed to them. Here we review these discoveries, which we believe add to a growing recognition that the human sense of smell and its potential role in social interactions have been underappreciated. However, we also critically evaluate the current evidence, with a particular focus on methodology and the interpretation of emotional odour studies. We argue that while the evidence convincingly indicates that humans retain a capacity for olfactory communication of emotion, the extent to which this occurs in ordinary social interaction remains an open question. Future studies should place fewer restrictions on participant selection and lifestyle and adopt more realistic experimental designs. We also need to devote more consideration to underlying mechanisms and to recognise the constraints that these may place on effective communication. Finally, we outline some promising approaches to address these issues, and raise some broader theoretical questions that such approaches may help us to answer.
The western Antarctic Peninsula is facing rapid environmental changes and many recent publications stress the need to gain new knowledge regarding ecosystems responses to these changes. In the framework of the Belgica 121 expedition, we tested the use of a nimble vessel with a moderate environmental footprint as an approach to tackle the urgent needs of the Southern Ocean research community in terms of knowledge regarding the levels of marine biodiversity in shallow areas and the potential impacts of retreating glaciers on this biodiversity in combination with increasing tourism pressure. We discuss the strengths and drawbacks of using a 75’ (23 m) sailboat in this research framework, as well as its sampling and environmental efficiency. We propose that the scientific community considers this approach to 1) fill specific knowledge gaps and 2) improve the general coherence of the research objectives of the Antarctic scientific community in terms of biodiversity conservation and the image that such conservation conveys to the general public.
Catatonia, a severe neuropsychiatric syndrome, has few studies of sufficient scale to clarify its epidemiology or pathophysiology. We aimed to characterise demographic associations, peripheral inflammatory markers and outcome of catatonia.
Methods
Electronic healthcare records were searched for validated clinical diagnoses of catatonia. In a case–control study, demographics and inflammatory markers were compared in psychiatric inpatients with and without catatonia. In a cohort study, the two groups were compared in terms of their duration of admission and mortality.
Results
We identified 1456 patients with catatonia (of whom 25.1% had two or more episodes) and 24 956 psychiatric inpatients without catatonia. Incidence was 10.6 episodes of catatonia per 100 000 person-years. Patients with and without catatonia were similar in sex, younger and more likely to be of Black ethnicity. Serum iron was reduced in patients with catatonia [11.6 v. 14.2 μmol/L, odds ratio (OR) 0.65 (95% confidence interval (CI) 0.45–0.95), p = 0.03] and creatine kinase was raised [2545 v. 459 IU/L, OR 1.53 (95% CI 1.29–1.81), p < 0.001], but there was no difference in C-reactive protein or white cell count. N-Methyl-d-aspartate receptor antibodies were significantly associated with catatonia, but there were small numbers of positive results. Duration of hospitalisation was greater in the catatonia group (median: 43 v. 25 days), but there was no difference in mortality after adjustment.
Conclusions
In the largest clinical study of catatonia, we found catatonia occurred in approximately 1 per 10 000 person-years. Evidence for a proinflammatory state was mixed. Catatonia was associated with prolonged inpatient admission but not with increased mortality.
In a seminal paper, Stallings introduced folding of morphisms of graphs. One consequence of folding is the representation of finitely-generated subgroups of a finite-rank free group as immersions of finite graphs. Stallings’s methods allow one to construct this representation algorithmically, giving effective, algorithmic answers and proofs to classical questions about subgroups of free groups. Recently Dani–Levcovitz used Stallings-like methods to study subgroups of right-angled Coxeter groups, which act geometrically on CAT(0) cube complexes. In this paper we extend their techniques to fundamental groups of non-positively curved cube complexes.
Posttraumatic stress disorder (PTSD) is traditionally understood as a disorder that occurs more commonly in women than in men, and in younger age groups than in older age groups. The objective of this study was to determine if these patterns are also observed in relation to International Classification of Diseases (ICD-11) PTSD and complex PTSD (CPTSD).
Methods
Secondary data analysis was performed using data collected from three nationally representative samples from the Republic of Ireland (N = 1,020), the United States (N = 1,839), and Israel (N = 1,003), and one community sample from the United Kingdom (N = 1,051).
Results
Estimated prevalence rates of ICD-11 PTSD were higher in women than in men in each sample, and at a level consistent with existing data derived from Diagnostic and Statistics Manual of Mental Disorders (DSM)-based models of PTSD. Furthermore, rates of ICD-11 PTSD were generally lower in older age groups for men and women. For CPTSD, there was inconsistent evidence of sex and age differences, and some indication of a possible interaction between these two demographic variables.
Conclusions
Despite considerable revisions to PTSD in ICD-11, the same sex and age profile was observed to previous DSM-based models of PTSD. CPTSD, however, does not appear to show the same sex and age differences as PTSD. Theoretical models that seek to explain sex and age differences in trauma-related psychopathology may need to be reconsidered given the distinct effects for ICD-11 PTSD and CPTSD.
Wavelength-dispersive X-ray (WDX) spectroscopy was used to measure silicon atom concentrations in the range 35–100 ppm [corresponding to (3–9) × 1018 cm−3] in doped AlxGa1–xN films using an electron probe microanalyser also equipped with a cathodoluminescence (CL) spectrometer. Doping with Si is the usual way to produce the n-type conducting layers that are critical in GaN- and AlxGa1–xN-based devices such as LEDs and laser diodes. Previously, we have shown excellent agreement for Mg dopant concentrations in p-GaN measured by WDX with values from the more widely used technique of secondary ion mass spectrometry (SIMS). However, a discrepancy between these methods has been reported when quantifying the n-type dopant, silicon. We identify the cause of discrepancy as inherent sample contamination and propose a way to correct this using a calibration relation. This new approach, using a method combining data derived from SIMS measurements on both GaN and AlxGa1–xN samples, provides the means to measure the Si content in these samples with account taken of variations in the ZAF corrections. This method presents a cost-effective and time-saving way to measure the Si doping and can also benefit from simultaneously measuring other signals, such as CL and electron channeling contrast imaging.
A profound characteristic of field cancerization is alterations in chromatin packing. This study aimed to quantify these alterations using electron microscopy image analysis of buccal mucosa cells of laryngeal, esophageal, and lung cancer patients. Analysis was done on normal-appearing mucosa, believed to be within the cancerization field, and not tumor itself. Large-scale electron microscopy (nanotomy) images were acquired of cancer patients and controls. Within the nuclei, the chromatin packing of euchromatin and heterochromatin was characterized. Furthermore, the chromatin organization was quantified through chromatin packing density scaling. A significant difference was found between the cancer and control groups in the chromatin packing density scaling parameter for length scales below the optical diffraction limit (200 nm) in both the euchromatin (p = 0.002) and the heterochromatin (p = 0.006). The chromatin packing scaling analysis also indicated that the chromatin organization of cancer patients deviated significantly from the control group. They might allow for novel strategies for cancer risk stratification and diagnosis with high sensitivity. This could aid clinicians in personalizing screening strategies for high-risk patients and follow-up strategies for treated cancer patients.
The occurrence of nonlocal objects, raw materials, and ideas in the southwestern United States (U.S. SW) has long been recognized as evidence of interaction between prehispanic peoples of this region and those of greater Mesoamerica. Although many archaeologists have analyzed the directionality and potential means by which these objects and concepts moved across the landscape, few have assessed the degree to which Mesoamerican practices and traditional assemblages remained intact as the artifacts and ideas moved farther from their places of origin. The current study analyzes the distribution and deposition of blue-green stone mosaics, a craft technology that was well established in Mesoamerica by the Late Preclassic period (300 BC–AD 250) and spread to the U.S. SW by the start of the Hohokam Pioneer period (AD 475). We assess the spatial distribution, contextual deposition, and morphology of mosaics at sites within Hohokam Canal System 2, located in the Phoenix Basin of Arizona. We use these data to infer mosaics’ social value and function within Hohokam social structure. Analyses suggest that, although the technology of mosaic making may have originated in Mesoamerica, the contexts and ways in which mosaics were used in the Hohokam regional system were decidedly Hohokam.
This collection of essays highlights innovative work in the developing field of media archaeology. It explores the relationship between theory and practice and the relationship between media archaeology and other disciplines. There are three sections to the collection proposing new possible fields of research for media studies: Media Archaeological Theory; Experimental Media Archaeology; Media Archaeology at the Interface. The book includes essays from acknowledged experts in this expanding field, such as Thomas Elsaesser, Wanda Strauven and Jussi Parikka.
Many studies document cognitive decline following specific types of acute illness hospitalizations (AIH) such as surgery, critical care, or those complicated by delirium. However, cognitive decline may be a complication following all types of AIH. This systematic review will summarize longitudinal observational studies documenting cognitive changes following AIH in the majority admitted population and conduct meta-analysis (MA) to assess the quantitative effect of AIH on post-hospitalization cognitive decline (PHCD).
Methods:
We followed Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines. Selection criteria were defined to identify studies of older age adults exposed to AIH with cognitive measures. 6566 titles were screened. 46 reports were reviewed qualitatively, of which seven contributed data to the MA. Risk of bias was assessed using the Newcastle–Ottawa Scale.
Results:
The qualitative review suggested increased cognitive decline following AIH, but several reports were particularly vulnerable to bias. Domain-specific outcomes following AIH included declines in memory and processing speed. Increasing age and the severity of illness were the most consistent risk factors for PHCD. PHCD was supported by MA of seven eligible studies with 41,453 participants (Cohen’s d = −0.25, 95% CI [−0.02, −0.49] I2 35%).
Conclusions:
There is preliminary evidence that AIH exposure accelerates or triggers cognitive decline in the elderly patient. PHCD reported in specific contexts could be subsets of a larger phenomenon and caused by overlapping mechanisms. Future research must clarify the trajectory, clinical significance, and etiology of PHCD: a priority in the face of an aging population with increasing rates of both cognitive impairment and hospitalization.