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  • Cited by 123
Publisher:
Cambridge University Press
Online publication date:
May 2010
Print publication year:
2009
Online ISBN:
9780511596582

Book description

This book is a completely revised new edition of the definitive reference on disorders of hemoglobin. Authored by world-renowned experts, the book focuses on basic science aspects and clinical features of hemoglobinopathies, covering diagnosis, treatment, and future applications of current research. While the second edition continues to address the important molecular, cellular, and genetic components, coverage of clinical issues has been significantly expanded, and there is more practical emphasis on diagnosis and management throughout. The book opens with a review of the scientific underpinnings. Pathophysiology of common hemoglobin disorders is discussed next in an entirely new section devoted to vascular biology, the erythrocyte membrane, nitric oxide biology, and hemolysis. Four sections deal with α and β thalassemia, sickle cell disease, and related conditions, followed by special topics. The second edition concludes with current and developing approaches to treatment, incorporating new agents for iron chelation, methods to induce fetal hemoglobin production, novel treatment approaches, stem cell transplantation, and progress in gene therapy.

Reviews

'This book is an excellent and truly extraordinary achievement of the editors and the authors. It is certainly a definitive reference work on the various disorders of hemoglobin. It is a must-have and a keepsake for any research scientist, professors seeking broader and deeper knowledge on the subject, or insight from the authors who are world-renowned experts. It is also a very valuable resource for any physician treating patients who have any disease relating to or resulting from hemoglobin disorders.'

Nano Khilnani Source: Biz India

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