R. E. Smalley (1985 Nobel Laureate for discovery of C60) provided the humanity’s top ten important issues for next 50 years in 2005, which are energy, water, food, environment, poverty, terrorism & war, disease, education, democracy, and population. In the past five years, the people has realized that with exhaustion of fossil fuel energy, global warming, population growth, and etc., the energy challenge & revolution is the most important issue. In order to solve this problem, many governments in the world have been developing the very important projects dealing with collecting, emitting, and manipulating energy. This paper reviewed the recent progress of these projects such as generation of renewable energies and save energies, especially focus on thin film solar cells, LEDs and smart power and grid, which including III-V materials on Si or ceramic substrates for high efficiency thin film solar cell and high power, high brightness and high efficiency LEDs, as well as smart control of mixture of electric, thermal and other energies. The Building Integrated Photovoltaics (BIPV) and City Integrated LEDs (CILED) will be most important manufacturing in this century.