To send content items to your account,
please confirm that you agree to abide by our usage policies.
If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account.
Find out more about sending content to .
To send content items to your Kindle, first ensure email@example.com
is added to your Approved Personal Document E-mail List under your Personal Document Settings
on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part
of your Kindle email address below.
Find out more about sending to your Kindle.
Note you can select to send to either the @free.kindle.com or @kindle.com variations.
‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi.
‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.
Despite the significant health disparities experienced by lesbian, gay, bisexual, and transgender (LGBT) populations, few investigators affiliated with the National Institutes of Health-funded Clinical and Translational Science Award Programs are conducting research related to this underserved population. We provide recommendations shared during a half-day workshop aimed at increasing researcher readiness to conduct LGBT research. This workshop was presented as part of a series on conducting research with underserved populations offered by the Recruitment, Retention, and Community Engagement Program of the Center for Clinical and Translational Science at the University of Illinois at Chicago. Six LGBT health research experts provided focused presentations. The workshop presentations included a summary of significant health inequality issues, theoretical models relevant to research on LGBT health, best practices in measuring sexual orientation and gender identity, recommendations for recruitment and retention, a discussion of community engagement, and ethical considerations in conducting LGBT research. We provide a summary of recommendations to guide future research, training, and public policy related to LGBT health. The information can increase capacity among Clinical and Translational Science Award affiliated researchers in conducting research in this special population.
Highly anomalous platinum-group element (PGE) concentrations in the podiform chromitites at the Cliff and Harold's Grave localities in the Shetland ophiolite complex have been well documented previously. The focus of this study is alluvial platinum-group minerals (PGM) located in small streams that drain from the PGE-rich chromitites. The placer PGM assemblage at Cliff is dominated by Pt-arsenides (64%) and Pd-antimonides (17%), with less irarsite–hollingworthite (11%) and minor Pd-sulfides, Pt–Pd–Cu and Pt–Fe alloys and laurite. Gold also occurs with the PGM. Alluvial PGM have average sizes of 20 µm × 60 µm, with sperrylite the largest grain identified at 110 µm in diameter, matching the range reported for the primary PGM in the source rocks. The placer assemblage contains more Pt-bearing and less Pd-bearing PGM compared with the rocks. The more resistant sperrylite and irarsite–hollingworthite grains which are often euhedral become more rounded further downstream whereas the less resistant Pd-antimonides which are commonly subhedral may become striated and etched. Less stable phases such as Pt- and Pd-oxides and other Ni-Cu-bearing phases located in the rocks (i.e. Ru-pentlandite, PtCu, Pd–Cu alloy) are absent in the placer assemblage. Also the scarce PGM (PdHg, Rh- and Ir-Sb) and Os in the rocks are absent. At Harold's Grave only three alluvial PGM (laurite, Ir, Os) and Au were recovered reflecting the limited release of IPGM from chromite grains in the rocks. In this cold climate with high rainfall, where erosion dominates over weathering, the PGM appear to have been derived directly from the erosion of the adjacent PGE-rich source rocks and there is little evidence of in situ growth of any newly formed PGM. Only the presence of dendritic pure Au and Pd-, Cu-bearing Au covers on the surface of primary minerals may indicate some local reprecipitation of these metals in the surficial conditions.
The star β CMa, prototype of the β CMa variables, is known to have been a double mode pulsator since the beginning of the century, with amplitudes of 12 and 7 km/sec for the 6.00 and 6.03 hour oscillations (Shobbrook, 1973). Recently, Dziembowski, Moskalik, and Pamyatnykh (1992) have produced models of B stars using OPAL opacities which have many radial and non-radial modes unstable. As only a few modes are observed in these stars, these authors suggest that modes might change amplitude in such a way that modes can appear, disappear, or be replaced by other modes. Based on unsubstantiated rumour that β CMa had, like α Vir, quit pulsating (Pesnell, priv. comm.), we undertook observations with the Mt. John University Observatory (New Zealand) echelle spectrograph and CCD camera on the 1-m McLelland telescope. We found that β CMa is still pulsating, but with reduced amplitude and substantial period change compared with earlier data.
In particular, quadratic ephemerides fit to all known times of spectroscopic maxima agree with our times of maxima [P1: HJD 2448611.8436; P2: HJD 2448611.8278] to better than two minutes, but an earlier linear ephemeris by Chappelier (1985) disagrees by over two hours. Our data is best fit with amplitudes of about 7 km/sec for both modes-this gives a nominal beat amplitude of nearly zero at the 49-day beat minimum (at a time when the linear ephemeris would have predicted a maximum amplitude). This may be the cause of the rumour mentioned above. Additional support for our conclusion of continuing pulsation comes from the fact that obvious line profile changes occur on the pulsation time scale.
Standards for organic pig production recommend that growing pigs are maintained on pasture. There is currently no information on the nutritional implications of such a system, since grazing intakes have not been recorded in pigs of this production stage. This study used n-alkane methodology previously validated in sows (Wilson et al., 1999) to measure the herbage intakes of individual pigs under such conditions.
The Taipan galaxy survey (hereafter simply ‘Taipan’) is a multi-object spectroscopic survey starting in 2017 that will cover 2π steradians over the southern sky (δ ≲ 10°, |b| ≳ 10°), and obtain optical spectra for about two million galaxies out to z < 0.4. Taipan will use the newly refurbished 1.2-m UK Schmidt Telescope at Siding Spring Observatory with the new TAIPAN instrument, which includes an innovative ‘Starbugs’ positioning system capable of rapidly and simultaneously deploying up to 150 spectroscopic fibres (and up to 300 with a proposed upgrade) over the 6° diameter focal plane, and a purpose-built spectrograph operating in the range from 370 to 870 nm with resolving power R ≳ 2000. The main scientific goals of Taipan are (i) to measure the distance scale of the Universe (primarily governed by the local expansion rate, H0) to 1% precision, and the growth rate of structure to 5%; (ii) to make the most extensive map yet constructed of the total mass distribution and motions in the local Universe, using peculiar velocities based on improved Fundamental Plane distances, which will enable sensitive tests of gravitational physics; and (iii) to deliver a legacy sample of low-redshift galaxies as a unique laboratory for studying galaxy evolution as a function of dark matter halo and stellar mass and environment. The final survey, which will be completed within 5 yrs, will consist of a complete magnitude-limited sample (i ⩽ 17) of about 1.2 × 106 galaxies supplemented by an extension to higher redshifts and fainter magnitudes (i ⩽ 18.1) of a luminous red galaxy sample of about 0.8 × 106 galaxies. Observations and data processing will be carried out remotely and in a fully automated way, using a purpose-built automated ‘virtual observer’ software and an automated data reduction pipeline. The Taipan survey is deliberately designed to maximise its legacy value by complementing and enhancing current and planned surveys of the southern sky at wavelengths from the optical to the radio; it will become the primary redshift and optical spectroscopic reference catalogue for the local extragalactic Universe in the southern sky for the coming decade.
Objectives: The aim of this study was to identify whether the three main primary progressive aphasia (PPA) variants would show differential profiles on measures of visuospatial cognition. We hypothesized that the logopenic variant would have the most difficulty across tasks requiring visuospatial and visual memory abilities. Methods: PPA patients (n=156), diagnosed using current criteria, and controls were tested on a battery of tests tapping different aspects of visuospatial cognition. We compared the groups on an overall visuospatial factor; construction, immediate recall, delayed recall, and executive functioning composites; and on individual tests. Cross-sectional and longitudinal comparisons were made, adjusted for disease severity, age, and education. Results: The logopenic variant had significantly lower scores on the visuospatial factor and the most impaired scores on all composites. The nonfluent variant had significant difficulty on all visuospatial composites except the delayed recall, which differentiated them from the logopenic variant. In contrast, the semantic variants performed poorly only on delayed recall of visual information. The logopenic and nonfluent variants showed decline in figure copying performance over time, whereas in the semantic variant, this skill was remarkably preserved. Conclusions: This extensive examination of performance on visuospatial tasks in the PPA variants solidifies some previous findings, for example, delayed recall of visual stimuli adds value in differential diagnosis between logopenic variant PPA and nonfluent variant PPA variants, and illuminates the possibility of common mechanisms that underlie both linguistic and non-linguistic deficits in the variants. Furthermore, this is the first study that has investigated visuospatial functioning over time in the PPA variants. (JINS, 2018, 24, 259–268)
Due to their extremely small luminosity compared to the stars they orbit, planets outside our own Solar System are extraordinarily difficult to detect directly in optical light. Careful photometric monitoring of distant stars, however, can reveal the presence of exoplanets via the microlensing or eclipsing effects they induce. The international PLANET collaboration is performing such monitoring using a cadre of semi-dedicated telescopes around the world. Their results constrain the number of gas giants orbiting 1–7 AU from the most typical stars in the Galaxy. Upgrades in the program are opening regions of “exoplanet discovery space” – toward smaller masses and larger orbital radii – that are inaccessible to the Doppler velocity technique.
Results of Einstein Observations of SS433 are discussed which address both the nature of the diffuse X-ray lobes and the relationships between SS433 and W50 as well as the time variability and nature of the central X-ray source. The diffuse X-ray lobes extend out to the quasi-spherical shell seen in the radio maps of W50 and suggest that the X-ray lobes are powered by the interaction of shock-heating from the SS433 jets and the denser material in the W50 shell. The central X-ray source in SS433 is time variable but only on timescales ≳ 500–1000 sec. Flares, in which the non-thermal spectrum hardens, are detected at two preferred phases in the 13.08 day binary orbit. Constraints on the central X-ray source size as well as a possible eclipse by the companion star suggest the compact object in SS433 may be an ~10 M⊙ black hole.
The 98 min eclipsing cataclysmic variable EX Hya possesses a strong 67 min modulation in its light. This has led to a discussion of EX Hya in the context of intermediate polar variables. The observed P/Ṗ of the 67 min modulation provides a useful constraint on EX Hya models. Here we report additional timing data obtained over the interval 1982 to 1985 which bears on this matter.
We present soft x-ray observations made with the Einstein Observatory Imaging Proportional Counter (IPC) of IC443, W44 and W49B (for details of the observatory and instruments see Giacconi et al. 1979). The x-ray emission from IC443 and W44 is clearly concentrated within the interior of the remnant with little or no evidence for a limb-brightened shell. Significant spectral differences are found across the x-ray images in both remnants which are interpreted as being due to a combination of differential absorption by molecular clouds and intrinsic spatial temperature variations. The distant remnant W49B is only just resolved in the IPC observations, but additional observations with the High Resolution Imager (HRI) indicate a similar “infilled” morphology to IC443 and W44.
We report far-infrared observations of [0 I], [C II] and [O III] fine structure emission lines toward the nuclei of M82 and 7 other galaxies with a high rate of star formation. The far-infrared line emission is bright, contains about 0.5% of the bolometric luminosity in the central 60″, and is spatially concentrated toward the nuclei. In these galaxies between 10 and 30% of the interstellar gas near the nuclei is contained in a warm, atomic component. This atomic gas is probably located at the UV photodissociated surfaces of molecular clouds. The neutral gas in M82 has a temperature of ∼ 200 K, hydrogen density of ∼ 3 × 104 cm−3 and is very clumpy, indicating that the interstellar medium in this star burst galaxy is very different from that in the disk of our own galaxy. We discuss the implications of the infrared observations for the interpretation of mm molecular lines and for star formation at the nuclei of star burst galaxies.
Current models of class II methanol masers are able to describe the brightnesses of the strongest masers and provide a basis for explaining observed line ratios. Determination of the physical parameters in the source requires observational data in many maser transitions. In order to provide observational constraints for models we searched for and detected 7 new methanol masers. This allowed us to constrain the physical parameters of the 3 sources with the greatest number of detected methanol maser lines: W3(OH), NGC6334F, and G345.01 + 1.79. The models accurately account for the fluxes of the bulk of the detected maser lines. Remaining discrepancies most probably reflect the fact that the most prominent components of the different maser lines are formed under different conditions. This is supported by comparison of the line profiles. We outline directions for future studies in the field.
Results of further calculations are presented to explore the non-linear, Zeeman overlap effect as the cause for the circular polarization of astrophysical masers. Emphasis is placed on the regime in which the Zeeman splitting is small and on the variation of the polarization with maser saturation.
Theoretical research on extragalactic masers (and hence this review) is almost entirely directed toward 22 GHz water masers in circumnuclear disks with the focus being the near ideal masing disk at the nucleus of the galaxy NGC4258. The discussion here is organized around (1) the excitation and conditions for the masers, (2) the spatial and spectral appearance of the maser emission, and (3) the mass accretion rate and structure of the disk. In addition, a summary is given of the basic physics (spectral linebreadths and maser polarization) that underlies certain interpretations of these and other astrophysical masers.
Introduction/Innovation Concept: University Departments of Emergency Medicine are responsible for the supervision of research and other scholarly projects for fellows, residents and students, though often lack resources to provide adequate input and oversight. Many departments cover large geographical areas and several programs. We piloted new research committee structures and processes to improve oversight and output of research projects. Methods: We created an interactive group supervision tool based around formation of a collaborative research committee, with rotating chairs from each program, to provide supervision and face to face interaction, and direction for research learners. Included were all Dalhousie University adult and pediatric emergency medicine residency and fellowship programs, as well as trauma and EMS programs across Nova Scotia, New Brunswick, and Prince Edward Island. In addition to providing expertise in clinical trial coordination, database management, research administration, grant applications and Research Ethics Board submissions, we have completed a 2-year pilot of our interactive group supervision tool for research projects. Curriculum, Tool, or Material: The interactive tool consists of a structured PICOD form; allocation of topic and research mentors; standardized yearly milestones from project development through presentation and publication; and regular video-conferenced and in-person interactive group sessions involving several project leads, as well as program research directors, researchers, and co-ordinators. To date, all participating program learners have engaged with the tool, with positive feedback from learners, supervisors and program directors. Conclusion: We report our development of a regional collaborative interactive group supervision tool, that maximizes expert resources in the provision of research and scholarly project supervision.
Despite a growing body of literature on integrated land–sea management (ILSM), very little critical assessment has been conducted in order to evaluate ILSM in practice on island systems. Here we develop indicators for assessing 10 integrated island management principles and evaluate the performance of planning and implementation in four island ILSM projects from the tropical Pacific across different governance structures. We find that where customary governance is still strongly respected and enabled through national legislation, ILSM in practice can be very effective at restricting access and use according to fluctuations in resource availability. However, decision-making under customary governance systems may be vulnerable to mismanagement. Government-led ILSM processes have the potential to design management actions that address the spatial scale of ecosystem processes and threats within the context of national policy and legislation, but may not fully capture broad stakeholder interests, and implementation may be poorly coordinated across highly dispersed island archipelagos. Private sector partnerships offer unique opportunities for resourcing island ILSM, although these are highly likely to be geared towards private sector interests that may change in the future and no longer align with community and/or national objectives. We identify consistent challenges that arise during island ILSM planning and implementation and offer recommendations for improvement.
Deep observations of the cosmic microwave background (CMB) have been made at 10 GHz with beamwidths of 5° and 8° using a triple-beam technique, which greatly reduces atmospheric effects. Significant signals are detected with an rms of ΔT/T ~ 4×10−5. These signals could be intrinsic to the CMB and are providing fundamental information about galaxy formation in the early universe. A component of this 10 GHz emission may be coming from galactic synchrotron features. This galactic contribution will be elucidated in forthcoming 15 and 30 GHz observations.
The dates listed were obtained using a stainless steel counter with an active volume of 1.3 L and a background of 16.3 cpm at an absolute filling pressure of 152 cm Hg. The present proportional counter in use is made of O.F.H.C. copper, and has an active volume of 1.25 L and a background of 5.2 cpm, at an absolute counter filling pressure of 152 cm Hg. CO2 is used as the counting gas and the counter is filled to a pressure of between 76 cm and 228 cm of Hg (depending on the sample size) at a temperature of 23 ± 0.3°C. The counter is shielded, starting from the top, by 5 cm of lead and 26 cm of iron, and is surrounded by an array of 22 Geiger tubes, and then finally by 2.5 cm of mercury. The thickness of the sides and base is greater than 10 cm of iron. As yet no neutron shielding is used and this probably accounts for the large fluctuations of background with barometric pressure (0.32 cpm per 1 cm Hg change in the pressure).
When children have marked problems with motor coordination, they often have problems with attention and impulse control. Here, we map the neuroanatomic substrate of motor coordination in childhood and ask whether this substrate differs in the presence of concurrent symptoms of attention-deficit/hyperactivity disorder (ADHD).
Participants were 226 children. All completed Diagnostic and Statistical Manual of Mental Disorders, fifth edition (DSM-5)-based assessment of ADHD symptoms and standardized tests of motor coordination skills assessing aiming/catching, manual dexterity and balance. Symptoms of developmental coordination disorder (DCD) were determined using parental questionnaires. Using 3 Tesla magnetic resonance data, four latent neuroanatomic variables (for the cerebral cortex, cerebellum, basal ganglia and thalamus) were extracted and mapped onto each motor coordination skill using partial least squares pathway modeling.
The motor coordination skill of aiming/catching was significantly linked to latent variables for both the cerebral cortex (t = 4.31, p < 0.0001) and the cerebellum (t = 2.31, p = 0.02). This effect was driven by the premotor/motor cortical regions and the superior cerebellar lobules. These links were not moderated by the severity of symptoms of inattention, hyperactivity and impulsivity. In categorical analyses, the DCD group showed atypical reduction in the volumes of these regions. However, the group with DCD alone did not differ significantly from those with DCD and co-morbid ADHD.
The superior cerebellar lobules and the premotor/motor cortex emerged as pivotal neural substrates of motor coordination in children. The dimensions of these motor coordination regions did not differ significantly between those who had DCD, with or without co-morbid ADHD.