Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
Hostname: page-component-848d4c4894-wzw2p Total loading time: 0 Render date: 2024-04-30T19:02:24.373Z Has data issue: false hasContentIssue false

Chapter 27 - Cleavage-Stage Transfer or Blastocyst Transfer?

from Section 5 - Embryo Selection and Transfer

Published online by Cambridge University Press:  04 January 2019

By
Evangelos G. Papanikolaou  and
Tatiana Chartomatzidou
Edited by
Gabor Kovacs ,
Anthony Rutherford  and
David K. Gardner
Gabor Kovacs
Affiliation:
Monash University, Victoria
Anthony Rutherford
Affiliation:
University of Leeds
David K. Gardner
Affiliation:
University of Melbourne
Get access

Summary

A summary is not available for this content so a preview has been provided. Please use the Get access link above for information on how to access this content.
Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Chapter
Information
How to Prepare the Egg and Embryo to Maximize IVF Success , pp. 314 - 326
Publisher: Cambridge University Press
Print publication year: 2019

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Gardner, DK and Lane, M. Alleviation of the “2- cell block” and development to the blastocyst of CFI mouse embryos: role of amino acids, EDTA and physical parameters. Hum Reprod 1996; 11:2701–12.Google Scholar
Gardner, DK. Development of serum-free media for the culture and transfer of human blastocysts. Hum Reprod 1998; 13 Suppl 4:218–25.Google Scholar
Edwards, RG, Brody, S. Principles and Practice of Assisted Human Reproduction. WB Saunders, Philadelphia, 1995.Google Scholar
della Ragione, T, Verheyen, G, Papanikolaou, EG et al. Developmental stage on day –5 and fragmentation rate on day –3 can influence the implantation potential of top-quality blastocysts in IVF cycles with single embryo transfer. Reprod Biol Endocrinol 2007; 5:2.CrossRefGoogle ScholarPubMed
Gardner, DK and Schoolcraft, WB. In vitro culture of human blastocysts. In: Jansen, R, Mortimer, D (eds.) Toward Reproductive Certainty: Fertility and Genetics Beyond. Parthenon Publishing, Carnforth, UK, 1999, pp. 378–88.Google Scholar
Papanikolaou, EG, Kolibianakis, EM, Tournaye, H et al.Live birth rates after transfer of equal number of blastocysts or cleavage-stage embryos in IVF. A systematic review and meta-analysis. Hum Reprod 2008; 23:91–99.Google Scholar
Wilson, M, Hartke, K, Kiehl, M et al. Transfer of blastocysts and morulae on day 5. Fertil Steril 2004; 82:327–33.CrossRefGoogle ScholarPubMed
Fragouli, E, Alfarawati, S, Spath, K, Wells, D. Morphological and cytogenetic assessment of cleavage and blastocyst stage embryos. Mol Hum Reprod 2014; 20, 117–26.Google Scholar
Staessen, C, Platteau, P, Van Assche, E et al. Comparison of blastocyst transfer with or without preimplantation genetic diagnosis for aneuploidy screening in couples with advanced maternal age: a prospective randomized controlled trial. Hum Reprod 2004; 19:2849–58.Google Scholar
Blake, DA, Proctor, M, Johnson, NP The merits of blastocyst versus cleavage stage embryo transfer: a Cochrane review. Hum Reprod 2004;19:795–780.Google Scholar
Glujovsky, D, Farquhar, C, Quinteiro Retamar, AM, Alvarez Sedo, CR, Blake, D. Cleavage stage versus blastocyst stage embryo transfer in assisted reproductive technology. Cochrane Database of Systematic Reviews 2016, Issue 6. Art. No.: CD002118.CrossRefGoogle Scholar
Maheshwari, A, Hamilton, M, Bhattacharya, S. Should we be promoting embryo transfer at blastocyst stage? Reproductive BioMedicine Online 2016; 32:142–46.Google Scholar
Papanikolaou, EG, D’haeseleer, E, Verheycn, G et al. Live birth rate is significantly higher after blastocyst transfer than after cleavage-stage transfer when at least four embryos are available on day 3 of culture. A randomized prospective study. Human Reprod 2005; 20:3198–203.Google ScholarPubMed
Papanikolaou, EG, Camus, M, Fatemi, HM et al. Early pregnancy loss is significantly higher after day 3 single embryo transfer than after day 5 single blastocyst transfer in GnRH antagonist stimulated IVF cycles. Reprod Biomed Online. 2006;12:60–65.Google Scholar
Kaur, P, Swarankar, ML, Maheshwari, M, Acharya, V. A comparative study between cleavage stage embryo transfer at day 3 and blastocyst stage transfer at day 5 in IVF/ICSI on clinical pregnancy rates. Indian Journal of Clinical Practice 2014; 24:663–67.Google Scholar
Aziminekoo, E, Mohseni Salehi, MS, Kalantari, V et al. Pregnancy outcome after blastocyst stage transfer comparing to early cleavage stage embryo transfer. Gynecol Endocrinol 2015; 31:880–84.Google Scholar
Fernández-Shaw, S, Cercas, R, Brana, C, Villas, C, Pons, I. Ongoing and cumulative pregnancy rate after cleavage-stage versus blastocyst-stage embryo transfer using vitrification for cryopreservation: impact of age on the results. J Assist Reprod Genet 2015; 32:177–84.CrossRefGoogle ScholarPubMed
Yang, Z, Liu, J, Collins, GS et al. Selection of single blastocysts for fresh transfer via standard morphology assessment alone and with array CGH for good prognosis IVF patients: results from a randomized pilot study. Mol Cytogenet 2012;5:1–8.Google Scholar
Forman, EJ, Hong, KH, Ferry, KM et al. In vitro fertilization with single euploid blastocyst transfer: a randomized controlled trial. Fertil Steril 2013b; 100:100–07. e101.Google Scholar
Scott, RT Jr, Upham, KM, Forman, EJ et al. Blastocyst biopsy with comprehensive chromosome screening and fresh embryo transfer significantly increases in vitro fertilization implantation and delivery rates: a randomized controlled trial. Fertil Steril 2013a; 100: 697–703.Google Scholar
Kedem, A, Haas, J, Geva, LL et al. Ongoing pregnancy rates in women with low and extremely low AMH levels. A multivariate analysis of 769 cycles. He B, ed. PLoS ONE. 2013;8:e81629.Google Scholar
Vitthala, S, Gelbaya, TA, Brison, DR, Fitzgerald, CT, Nardo, LG. The risk of monozygotic twins after assisted reproductive technology: a systematic review and meta-analysis. Hum Reprod Update. 2009; 15: 45–55.Google Scholar
Papanikolaou, EG, Fatemi, H, Venetis, C et al. Monozygotic twinning is not increased after single blastocyst transfer compared with single cleavage-stage embryo transfer. Fertil Steril 2010: 93:592–97.CrossRefGoogle Scholar
Abuzeid, MI, Bolonduro, O, La Chance, J et al. Cumulative live birth rate and assisted reproduction: impact of female age and transfer day. Facts Views Vis Obgyn 2014;6:145–49.Google Scholar
Dar, S, Lazer, T, Shah, PS, Librach, CL. Neonatal outcomes among singleton births after blastocyst versus cleavage stage embryo transfer: a systematic review and meta-analysis. Hum Reprod Update. 2014;20:439–48.Google Scholar
Maheshwari, A and Bhattacharya, S. Elective frozen replacement cycles for all: ready for prime time? Hum Reprod 2013;28:6–9.Google Scholar
Rizos, D, Lonergan, P, Boland, MP et al. Analysis of differential messenger RNA expression between bovine blastocysts produce in different culture systems: implications for blastocyst quality. Biol Reprod 2002; 66:589–95.Google Scholar
Oron, G, Esh-Broder, E, Son, WY. Holzer, H, Tulandi, T. Predictive value of maternal serum human chorionic gonadotropin levels in pregnancies achieved by in vitro fertilization with single cleavage and single blastocyst embryo transfers. Fertil Sterility 2015;103:1526–31.Google Scholar
Makinen, S, Soderstrom-Anttila, V, Vainio, J, Suikkari, AM, Tuuri, T. Does long in vitro culture promote large for gestational age babies? Hum Reprod 2013;28:828–34.Google Scholar
Zhu, J, Lin, S, Li, M et al. Effect of in vitro culture period on birthweight of singleton newborns. Hum Reprod 2014; 29:448–54.Google Scholar
Chang, HJ, Lee, JR, Jee, BC, Suh, CS, Kim, S H. Impact of blastocyst transfer on offspring sex ratio and the monozygotic twinning rate: a systematic review and meta-analysis. Fertil Steril 2009;91:2381–90.CrossRefGoogle Scholar
Racowsky, C, Jackson, KV, Cekleniak, NA et al. The number of eight-cell embryos is a key determinant for selecting day 3 or day 5 transfer. Fertil Steril 2000; 73:558–64 .Google Scholar
Kyrou, D, Kolibianakis, EM, Venetis, CA et al. How to improve the probability of pregnancy in poor responders undergoing in vitro fertilization: a systematic review and meta- analysis. Fertil Steril 2009;91:749–66.Google Scholar
Egea, RR, Puchalt, NG, Escrivá, MM, Varghese, AC. OMICS: Current and future perspectives in reproductive medicine and technology. J Hum Reprod Sci 2014; 7:73–92.Google Scholar
Talbi, S, Hamilton, AE, Vo, KC et al. Molecular phenotyping of human endometrium distinguishes menstrual cycle phases and underlying biological processes in normo-ovulatory women. Endocrinology 2006;147:1097–1121.Google Scholar
Ruiz-Alonso, M, Blesa, D, Simón, C. The genomics of the human endometrium. Biochim Biophys Acta. 2012;1822:1931–42.Google Scholar

Save book to Kindle

To save this book to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×