Skip to main content Accessibility help
×
Hostname: page-component-848d4c4894-2pzkn Total loading time: 0 Render date: 2024-05-25T10:03:45.578Z Has data issue: false hasContentIssue false

Chapter Fifty Six - Endovascular Treatment of Acute Ischemic Stroke

from Treatment

Published online by Cambridge University Press:  13 December 2022

Louis R. Caplan
Affiliation:
Beth Israel Deaconess Medical Centre
Aishwarya Aggarwal
Affiliation:
John F. Kennedy Medical Center
Get access

Summary

The interventional treatment of acute ischemic stroke (AIS) began in the 1950s, when surgical approaches for cervical carotid disease (thrombendarteriectomy, bypass with vascular bridging graft, and diseased arterial segment resections) were first reported. In 1958, Bernard Sussman and Tom Fitch reported the first three cases of intraarterial (IA) infusion of fibrinolytics (fibrinolysin) to treat cerebral arterial occlusions [1]. The results were angiographically and clinically suboptimal but paved the way for future endovascular therapy investigations. In 1983, Herman Zeumer and his German colleagues reported the feasibility of IA fibrinolytic infusion (streptokinase) in five patients who had basilar artery occlusions (BAO) through 3F catheters placed in the distal cervical vertebral artery [2]. Zeumer was an early neuroradiologist who often thought “outside the box” and was an important innovator. Successful recanalization with clinical improvement occurred in three patients. A year later, the same authors reported the first two cases of IA infusion of urokinase into the internal carotid artery (ICA) to treat ICA occlusions [3].

Type
Chapter
Information
Stories of Stroke
Key Individuals and the Evolution of Ideas
, pp. 551 - 561
Publisher: Cambridge University Press
Print publication year: 2022

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Notes and References

Sussman, BJ, Fitch, TS. Thrombolysis with fibrinolysin in cerebral arterial occlusion. J. Am. Med. Assoc. 1958;167:17051709.CrossRefGoogle ScholarPubMed
Zeumer, H, Hacke, W, Ringelstein, EB. Local intraarterial thrombolysis in vertebrobasilar thromboembolic disease. AJNR Am. J. Neuroradiol. 1983;4:401404.Google Scholar
Zeumer, H, Hündgen, R, Ferbert, A, Ringelstein, EB. Local intraarterial fibrinolytic therapy in inaccessible internal carotid occlusion. Neuroradiology 1984;26:315317.CrossRefGoogle ScholarPubMed
Mori, E, Tabuchi, M, Yoshida, T, Yamadori, A. Intracarotid urokinase with thromboembolic occlusion of the middle cerebral artery. Stroke 1988;19:802812.CrossRefGoogle ScholarPubMed
Hacke, W, Zeumer, H, Ferbert, A, Brückmann, H, del Zoppo, GJ. Intra-arterial thrombolytic therapy improves outcome in patients with acute vertebrobasilar occlusive disease. Stroke 1988;19:12161222.Google Scholar
del Zoppo, GJd, Higashida, RT, Furlan, AJ. PROACT: A phase II randomized trial of recombinant pro-urokinase by direct arterial delivery in acute middle cerebral artery stroke. Stroke 1998;29:411.Google Scholar
Furlan, A, Higashida, R, Wechsler, L, Gent, M, Rowley, H, Kase, C, et al. Intra-arterial prourokinase for acute ischemic stroke. The PROACT II study: A randomized controlled trial. Prolyse in acute cerebral thromboembolism. JAMA 1999;282:20032011.Google Scholar
Ogawa, A, Mori, E, Minematsu, K, et al. Randomized trial of intraarterial infusion of urokinase within 6 hours of middle cerebral artery stroke: The Middle Cerebral Artery Embolism Local Fibrinolytic Intervention Trial (MELT) Japan. Stroke 2007;38:26332639.Google Scholar
Lewandowski, CA, Frankel, M, Tomsick, TA, et al. Combined intravenous and intra-arterial r-tPA versus intra-arterial therapy of acute ischemic stroke: Emergency Management of Stroke (EMS) bridging trial. Stroke 1999;30:25982605.Google ScholarGoogle ScholarGoogle Scholar
Broderick, JP, Palesch, YY, Demchuk, AM, et al. Endovascular therapy after intravenous t-PA versus t-PA alone for stroke. N. Engl. J. Med. 2013;368:893903.Google ScholarGoogle ScholarGoogle Scholar
Nogueira, RG, Schwamm, LH, Hirsch, JA. Endovascular approaches to acute stroke, part 1: Drugs, devices, and data. AJNR Am. J. Neuroradiol. 2009;30:649661.CrossRefGoogle ScholarPubMed
Smith, WS, Sung, G, Saver, J, Budzik, R, Duckwiler, G, Liebeskind, DS, et al. Mechanical thrombectomy for acute ischemic stroke: Final results of the Multi MERCI trial. Stroke 2008;39:12051212.Google Scholar
The Penumbra Pivotal Stroke Trial: Safety and effectiveness of a new generation of mechanical devices for clot removal in intracranial large vessel occlusive disease. Stroke 2009;40:2761–2768.CrossRefGoogle Scholar
Castaño, C, Dorado, L, Guerrero, C, et al. Mechanical thrombectomy with the Solitaire AB device in large artery occlusions of the anterior circulation: A pilot study. Stroke 2010;41:18361840.Google Scholar
Roth, C, Papanagiotou, P, Behnke, S, et al. Stent-assisted mechanical recanalization for treatment of acute intracerebral artery occlusions. Stroke 2010;41:25592567.Google Scholar
Saver, JL, Jahan, R, Levy, EI, et al. Solitaire flow restoration device versus the Merci retriever in patients with acute ischaemic stroke (SWIFT): A randomised, parallel-group, non-inferiority trial. Lancet 2012;380:12411249.Google ScholarGoogle Scholar
Examples include Goyal, M, Demchuk, AM, Menon, BK, et al. Randomized assessment of rapid endovascular treatment of ischemic stroke. N. Engl. J. Med. 2015;372:10191030.Google ScholarGoogle ScholarGoogle Scholar
Berkhemer, OA, Fransen, PS, Beumer, D, et al. for the MR CLEAN Investigators. A randomized trial of intraarterial treatment for acute ischemic stroke. N. Engl. J. Med. 2015;372:1120.Google Scholar
Goyal, M, Demchuk, AM, Menon, BK, et al. Randomized assessment of rapid endovascular treatment of ischemic stroke. N. Engl. J. Med. 2015;372:10191030.CrossRefGoogle ScholarPubMed
Saver, JL, Goyal, M, Bonafe, A, et al. Stent-retriever thrombectomy after intravenous t-PA vs. T-PA alone in stroke. N. Engl. J. Med. 2015;372:22852295.CrossRefGoogle ScholarPubMed
Jovin, TG, Chamorro, A, Cobo, E, et al. Thrombectomy within 8 hours after symptom onset in ischemic stroke. N. Engl. J. Med. 2015;372:22962306.Google Scholar
Campbell, BC, Mitchell, PJ, Kleinig, TJ, et al. Endovascular therapy for ischemic stroke with perfusion-imaging selection. N. Engl. J. Med. 2015;372:10091018.CrossRefGoogle ScholarPubMed
Bracard, S, Ducrocq, X, Mas, JL, et al. Mechanical thrombectomy after intravenous alteplase versus alteplase alone after stroke (THRACE): A randomised controlled trial. Lancet Neurol. 2016;15:11381147.CrossRefGoogle ScholarPubMed
Muir, KW, Ford, GA, Messow, CM, et al. Endovascular therapy for acute ischaemic stroke: The Pragmatic Ischaemic Stroke Thrombectomy Evaluation (PISTE) randomised, controlled trial. J. Neurol. Neurosurg. Psychiatry 2017;88:3844.Google Scholar
Goyal, M, Menon, BK, van Zwam, WH, et al. Endovascular thrombectomy after large-vessel ischaemic stroke: A meta-analysis of individual patient data from five randomised trials. Lancet 2016;387:17231731.CrossRefGoogle ScholarPubMed
Martins, SO, Mont’Alverne, F, Rebello, LC, et al. Thrombectomy for stroke in the public health care system of Brazil. N. Engl. J. Med. 2020;382:23162326.CrossRefGoogle ScholarPubMed
Nogueira, RG, Jadhav, AP, Haussen, DC, et al. Thrombectomy 6 to 24 hours after stroke with a mismatch between deficit and infarct. N. Engl. J. Med. 2017;378:1121.Google Scholar
Albers, GW, Marks, MP, Kemp, S, et al. Thrombectomy for stroke at 6 to 16 hours with selection by perfusion imaging. N. Engl. J. Med. 2018;378:708718.Google Scholar
Jovin, T, Nogueira, RG, Lansberg, M, et al. Thrombectomy for anterior circulation stroke beyond 6 hours from time last known well: The AURORA (analysis of pooled data from randomized studies of thrombectomy more than 6 hours after last known well) collaboration. Lancet 2021, in press.Google Scholar
Lapergue, B, Blanc, R, Gory, B, et al. Effect of endovascular contact aspiration vs stent retriever on revascularization in patients with acute ischemic stroke and large vessel occlusion: The ASTER randomized clinical trial. JAMA 2017;318:443452.Google ScholarGoogle Scholar
Schönenberger, S, Hendén, PL, Simonsen, CZ, et al. Association of general anesthesia vs procedural sedation with functional outcome among patients with acute ischemic stroke undergoing thrombectomy: A systematic review and meta-analysis. JAMA 2019;322:12831293.Google Scholar
Mendez, B, Requena, M, Aires, A, et al. Direct transfer to angio-suite to reduce workflow times and increase favorable clinical outcome. Stroke 2018;49:27232727.Google Scholar
Liu, X, Dai, Q, Ye, R, et al. Endovascular treatment versus standard medical treatment for vertebrobasilar artery occlusion (BEST): An open-label, randomised controlled trial. Lancet Neurol. 2020;19:115122.Google ScholarGoogle Scholar
Yang, P, Zhang, Y, Zhang, L, et al. Endovascular thrombectomy with or without intravenous alteplase in acute stroke. N. Engl. J. Med. 2020;382:19811993.Google Scholar

Save book to Kindle

To save this book to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×