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Volume 223 - October 2023

Contents

Page 4 of 6

Book Review

Kaleidoscope

  • Kaleidoscope

  • Derek K. Tracy
  • Published online by Cambridge University Press:
    01 November 2023, pp. 529-530
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Book Review

Front Cover (OFC, IFC) and matter

  • BJP volume 223 issue 6 Cover and Front matter

  • Published online by Cambridge University Press:
    18 December 2023, pp. f1-f3
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Review

  • Psychosocial and behavioural interventions for the negative symptoms of schizophrenia: a systematic review of efficacy meta-analyses

  • Matteo Cella, Safina Roberts, Matthias Pillny, Marcel Riehle, Brian O'Donoghue, John Lyne, Paul Tomlin, Lucia Valmaggia, Antonio Preti
  • Published online by Cambridge University Press:
    15 March 2023, pp. 321-331
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  • Background

    Currently there is no first-line treatment recommended for the negative symptoms of schizophrenia. Psychosocial and behavioural interventions are widely used to reduce the burden of negative symptoms. Meta-analytic studies have summarised the evidence for specific approaches but not compared evidence quality and benefit.

    Aim

    To review and evaluate the evidence from meta-analytic studies of psychosocial and behavioural interventions for the negative symptoms of schizophrenia.

    Method

    A systematic literature search was undertaken to identify all meta-analyses evaluating psychosocial and behavioural interventions reporting on negative symptom outcomes in people with schizophrenia. Data on intervention, study characteristics, acceptability and outcome were extracted. Risk of bias was evaluated. Results were summarised descriptively, and evidence ranked on methodological quality.

    Results

    In total, 31 systematic reviews met the inclusion criteria evaluating the efficacy of negative symptom interventions on 33 141 participants. Exercise interventions showed effect sizes (reduction in negative symptoms) ranging from −0.59 to −0.24 and psychological interventions ranging from −0.65 to −0.04. Attrition ranged between 12% to 32%. Across the studies considered heterogeneity varied substantially (range 0–100). Most of the reviews were of very low to low methodological quality. Methodological quality ranking suggested that the effect size for cognitive remediation and exercise therapy may be more robust compared with other approaches.

    Conclusions

    Most of the interventions considered had a small-to-moderate effect size, good acceptability levels but very few had negative symptoms as the primary intervention target. To improve the confidence of these effect sizes being replicated in clinical settings future studies should minimise risk of bias.

Corrigendum

Book Review

Kaleidoscope

  • Kaleidoscope

  • Derek K. Tracy
  • Published online by Cambridge University Press:
    17 October 2023, pp. 497-498
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  • Kaleidoscope

  • Derek K. Tracy
  • Published online by Cambridge University Press:
    01 September 2023, pp. 450-451
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Back Cover (IBC, OBC) and matter

  • BJP volume 223 issue 6 Cover and Back matter

  • Published online by Cambridge University Press:
    18 December 2023, p. b1
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Analysis

Extra

  • Equanimity for anger: creating space for difficult emotions – Psychiatry in sacred texts

  • Michael Uebel
  • Published online by Cambridge University Press:
    01 November 2023, p. 503
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  • Manzoni and agoraphobia – Psychiatry in literature

  • Luca Cambioli, Michele Augusto Riva
  • Published online by Cambridge University Press:
    17 October 2023, p. 464
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Correspondence

Extra

  • Pink Floyd's ‘Comfortably Numb’: a clinical reflection – Psychiatry in music

  • Filippo Besana
  • Published online by Cambridge University Press:
    01 September 2023, p. 421
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Kaleidoscope

  • Kaleidoscope

  • Derek K. Tracy
  • Published online by Cambridge University Press:
    01 August 2023, pp. 399-400
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Extra

  • Phantasm and suicide – Psychiatry in movies

  • Shisei Tei, Junya Fujino
  • Published online by Cambridge University Press:
    01 November 2023, p. 517
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Reply

Page 4 of 6