A 14–year-old youth sustained an Injury to the left frontoparietal area, which was followed by evident change in personality and subsequently by an early-onset schizophrenia-like psychosis. Magnetic resonance imaging revealed ventricular dilatation, slightly more marked in the left hemisphere, and cortical atrophy. Some implications of this case for research on schizophrenia itself are discussed.

A student of chemistry was treated for thallium poisoning. Seven months after his ingestion of thallium, intelligence tests were performed on the patient and his non-identical twin brother, who was of similar educational background. These indicated severe deterioration in intellectual function of the patient, particularly in memory and performance abilities. Tests 13 months after ingestion showed little general improvement.

A patient with spasms of the neck, occurring when he turned his head to the left, responded to treatment with benzhexol. Cerebral blood flow imaging demonstrated reduced uptake in the right corpus striatum compared with the left. The study demonstrates the presence of an abnormality in the basal ganglia; it also illustrates response to drug treatment. Cerebral blood flow imaging may be useful in the detection of basal ganglia abnormalities in spasmodic torticollis and assist in the selection of cases which should be targeted for treatment with drugs.