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5 - Human Visual Plasticity: Lessons from Children Treated for Congenital Cataracts

from II - PLASTICITY IN CHILDHOOD

Published online by Cambridge University Press:  05 January 2013

By
Daphne Maurer  and
Terri Lewis
Edited by
Jennifer K. E. Steeves  and
Laurence R. Harris
Daphne Maurer
Affiliation:
McMaster University
Terri Lewis
Affiliation:
McMaster University
Jennifer K. E. Steeves
Affiliation:
York University, Toronto
Laurence R. Harris
Affiliation:
York University, Toronto
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Summary

At birth, infants can see only large objects of high contrast located in the central visual field. Over the next half year, basic visual sensitivity improves dramatically. The infant begins to perceive the direction of moving objects and stereoscopic depth, and to integrate the features of objects and faces. Nevertheless, it takes until about 7 years of age for acuity and contrast sensitivity to become as acute as those of adults and into adolescence for some aspects of motion and face processing to reach adult levels of expertise.

An important developmental question is whether, and to what extent, the improvements in vision during normal development depend on normal visual experience. To find out, we have taken advantage of a natural experiment: children born with dense, central cataracts in both eyes that block all patterned visual input to the retina. The children are treated by surgically removing the cataractous lenses and fitting the eyes with compensatory contact lenses that allow the first focused patterned visual input to reach the retina. In the studies summarized in this chapter, the duration of deprivation – from birth until the fitting of contact lenses after surgery – ranged from just a few weeks to most of the first year of life. In other cases, the child began with apparently normal eyes but developed dense bilateral cataracts postnatally that blocked visual input. As in the congenital cases, the cataractous lenses were removed and the eyes fitted with contact lenses.

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Plasticity in Sensory Systems , pp. 75 - 93
Publisher: Cambridge University Press
Print publication year: 2012

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References

Armstrong, V., Maurer, D., Ellemberg, D. and Lewis, T. L. (2011). Sensitivity to first- and second-order drifting gratings in 3-month-old infants. i-Perception, 2: 440–457.Google Scholar
Bavelier, D., Levi, D. M., Li, R. W., Dan, Y. and Hensch, T. K. (2010). Removing brakes on adult brain plasticity: from molecular to behavioral interventions. J. Neurosci., 30: 14964–14971.Google Scholar
Birch, E. E., Cheng, C., Stager, D. R.,Weakley, D. R. and Stager, D. R. (2009). The critical period for surgical treatment of dense congenital bilateral cataracts. J. AAPOS, 13: 67–71.Google Scholar
Blakemore, C. (1990). Vision: coding and efficiency. In Blakemore, C. (ed.), Maturation of Mechanisms for Efficient Spatial Vision, pp. 254–266. Cambridge: Cambridge University Press.
Blakemore, C. and Vital-Durand, F. (1983). Visual deprivation prevents the postnatal maturation of spatial contrast sensitivity neurons of the monkey's striate cortex. J. Physiol., 345: 40P.Google Scholar
Bonda, E., Petrides, M., Ostry, D. and Evans, A. (1996). Specific involvement of human parietal systems and the amygdala in the perception of biological motion. J. Neurosci., 16: 3737–3744.Google Scholar
Burton, H., Sinclair, R. J. and McLaren, D. G. (2004). Cortical activity to vibrotactile stimulation: an fMRI study in blind and sighted individuals. Hum. Brain Mapp., 23: 210–228.Google Scholar
Cashon, C. H. and Cohen, L. B. (2003). The construction, deconstruction, and reconstruction of infant face perception. In Pascalis, O. and Slater, A. (eds.), The Development of Face Processing in Infancy and Early Childhood: Current Perspectives, pp. 55–68. New York: Nova Science.
Collignon, O., Lassonde, M., Lepore, F., Bastien, D. and Veraart, C. (2007). Functional cerebral reorganization for auditory spatial processing and auditory substitution of vision in early blind subjects. Cereb. Cortex, 17: 457–465.Google Scholar
Collignon, O., Voss, P., Lassonde, M. and Lepore, F. (2009). Cross-modal plasticity for the spatial processing of sounds in visually deprived subjects. Exp. Brain Res., 192: 343–358.Google Scholar
Cowey, A. (2010). Visual system: how does blindsight arise?Curr. Biol., 20: R702–R704.Google Scholar
Crawford, M. J. L., Blake, R., Cool, S. J. and von Noorden, G. K. (1975). Physiological consequences of unilateral and bilateral eye closure in macaque: some further observation. Brain Res., 85: 150–154.Google Scholar
Crawford, M. L. J., Pesch, T. W., von Noorden, G. K., Harwerth, R. S. and Smith, E. L. (1991). Bilateral form deprivation in monkeys. Invest. Ophthalmol. Vis. Sci., 32: 2328–2336.Google Scholar
Cremieux, J., Orban, G. A., Duysens, J. and Amblard, B. (1987). Response properties of area 17 neurons in cats reared in stroboscopic illumination. J. Neurophysiol., 57: 1511–1535.Google Scholar
de Heering, A. and Maurer, D. (2012). The prosopagnosic profile of patients deprived of early vision by bilateral congenital cataracts. Poster presented at the meeting of the Vision Sciences Society, Naples.
Desimone, R. and Schein, S. J. (1987). Visual properties of neurons in area V4 of the macaque: sensitivity to stimulus form. J. Neurophysiol., 57: 835–868.Google Scholar
Dobkins, K. R. (2006). Enhanced red/green color input to motion processing in infancy: evidence for increasing dissociation of color and motion information during development. In Munakata, Y. and Johnson, M. H. (eds.), Processes of Change in Brain and Cognitive Development: Attention and Performance XXI, pp. 401–423. Oxford: Oxford University Press.
Egerton, A., Mehta, M. A., Montgomery, A. J., Lappin, J. M., Howes, O. D., Reeves, S. J., Cunningham, V. J. and Grasby, P. M. (2009). The dopaminergic basis of human behaviors: a review of molecular imaging studies. Neurosci. Biobehav. Rev., 33: 1109–1132.Google Scholar
Ellemberg, D., Lewis, T. L., Defina, N., Maurer, D., Brent, H. P.,Guillemot, J. P. and Lepore, F. (2005). Greater losses in sensitivity to second-order local motion than to first-order local motion after early visual deprivation in humans. Vision Res., 45: 2877–2884.Google Scholar
Ellemberg, D., Lewis, T. L., Maurer, D., Brar, S. and Brent, H. P. (2002). Better perception of global motion after monocular than after binocular deprivation. Vision Res., 42: 169–179.Google Scholar
Fantz, R. L. (1963). Pattern vision in newborn infants. Science, 140: 296–297.Google Scholar
Fantz, R. L., Ordy, J. and Udelf, M. (1962). Maturation of pattern vision in infants during the first six months. J. Comp. Physiol. Psychol., 55: 907–917.Google Scholar
Ferrari, P. F., Gallese, V., Rizzolatti, G. and Fogassi, L. (2003). Mirror neurons responding to the observation of ingestive and communicative mouth actions in the monkey ventral premotor cortex. Eur. J. Neurosci., 17: 1703–1714.Google Scholar
Gallant, J. L., Shoup, R. E. and Mazer, J. A. (2000). A human extrastriate area functionally homologous to macaque V4. Neuron, 27: 227–235.Google Scholar
Geldart, S., Mondloch, C. J.,Maurer, D., de Schonen, S. and Brent, H. P. (2002). The effect of early visual deprivation on the development of face processing. Dev. Sci., 5: 490–501.Google Scholar
Glass, G. V. and Hakstian, A. R. (1969). Measures of association in comparative experiments: their development and interpretation. Am. Educ. Res. J., 6: 403–414.Google Scholar
Grady, C., O'Craven, K., Mondloch, C., Lewis, T., Chiew, K. and Maurer, D. (2006). Abnormal extrastriate activity in response to faces, houses, and objects in adults deprived of form vision during infancy. Paper presented at the meeting of the Organization for Human Brain Mapping, Florence, Italy.
Green, C. S. and Bavelier, D. (2007). Action-video-game experience alters the spatial resolution of vision. Psychol. Sci., 18: 88–94.Google Scholar
Grèzes, J., Fonlupt, P., Bertenthal, B., Delon-Martin, C., Segebarth, C. and Decety, J. (2001). Does perception of biological motion rely on specific brain regions?Neuroimage, 13: 775–785.Google Scholar
Hadad, B. S., Maurer, D. and Lewis, T. L. (2011). Long trajectory for the development of sensitivity to global and biological motion. Dev. Sci., 14: 1330–1339.Google Scholar
Hadad, B. S., Maurer, D. and Lewis, T. L. (2012). Sparing of sensitivity to biological motion but not of global motion after early visual deprivation. Dev. Sci., 15(4): 474–481.Google Scholar
Hensch, T. K. (2005). Critical period plasticity in local cortical circuits. Nature Rev. Neurosci., 6: 877–688.Google Scholar
Iacoboni, M., Woods, R., Brass, M., Bekkering, H., Mazziotta, J. C. and Rizzolatti, G. (1999). Cortical mechanisms of human imitation. Science, 286: 2526–2528.Google Scholar
Jeffrey, B. G., Wang, Y. Z. and Birch, E. E. (2004). Altered global shape discrimination in deprivation amblyopia. Vision Res., 44: 167–177.Google Scholar
Jeon, S. T., Maurer, D., and Lewis, T. L. (in press). Video game training improves vision in adults with bilateral deprivation amblyopia. Seeing Perceiving.
Johansson, G. (1973). Visual perception of biological motion and a model for its analysis. Percept. Psychophys., 14: 201–211.Google Scholar
Koepp, M. J., Gunn, R. N., Lawrence, A. D., Cunningham, V. J., Dagher, A., Jones, T., Brooks, D. J., Bench, C. J. and Grasby, P. M. (1998). Evidence for striatal dopamine release during a video game. Nature, 393: 266–268.Google Scholar
Kugelberg, U. (1992). Visual acuity following treatment of bilateral congenital cataracts. Doc. Ophthal., 82: 211–215.Google Scholar
Le Grand, R., Mondloch, C. J., Maurer, D. and Brent, H. P. (2001). Neuroperception: early visual experience and face processing. Nature, 410: 890.Google Scholar
Le Grand, R., Mondloch, C. J., Maurer, D. and Brent, H. P. (2004). Impairment in holistic face processing following early visual deprivation. Psychol. Sci., 15: 762–768.Google Scholar
Levi, D. M. (2005). Perceptual learning in adults with amblyopia: a reevaluation of critical periods in human vision. Dev. Psychobiol., 46: 222–232.Google Scholar
Levi, D.M. and Li, R.W. (2009). Perceptual learning as a potential treatment for amblyopia: a mini-review. Vision Res., 49: 2535–2549.Google Scholar
Lewis, T. L., Ellemberg, D., Maurer, D., Dirks, M.,Wilkinson, F. and Wilson, H. R. (2004). A window on the normal development of sensitivity to global form in glass patterns. Perception, 33: 409–418.Google Scholar
Lewis, T. L., Ellemberg, D., Maurer, D.,Wilkinson, F.,Wilson, H. R., Dirks, M. and Brent, H. P. (2002). Sensitivity to global form in glass patterns after early visual deprivation in humans. Vision Res., 42: 939–948.Google Scholar
Lewis, T. L. and Maurer, D. (2009). Effects of early pattern deprivation on visual development. Optom. and Vis. Sci., 86: 640–646.Google Scholar
Lewis, T. L.,Maurer, D. and Brent, H. P. (1995). Development of grating acuity in children treated for unilateral or bilateral congenital cataract. Invest. Ophthalmol. Vis. Sci., 36:, 2080–2095.Google Scholar
Lundvall, A. and Kugelberg, U. (2002). Outcome after treatment for congenital bilateral cataract. Acta Ophthalmol. Scand., 80: 593–597.Google Scholar
Magnusson, G., Abrahamsson, M. and Sjöstrand, J. (2002). Changes in visual acuity from 4 to 12 years of age in children operated for bilateral congenital cataracts. Br. J. Ophthalmol., 86: 1385–1398.Google Scholar
Maurer, D., Ellemberg, D. and Lewis, T. L. (2006). Repeated measurements of contrast sensitivity reveal limits to visual plasticity after early binocular deprivation in humans. Neuropsychologia, 44: 2104–2112.Google Scholar
Maurer, D. and Hensch, T. (2012). Amblyopia: background to the special issue on stroke recovery. Dev. Psychobiol., 54: 224–238.Google Scholar
Maurer, D. and Lewis, T. L. (2001). Visual acuity: the role of visual input in inducing postnatal change. Clin. Neurosci. Res., 1: 239–247.Google Scholar
Maurer, D., Lewis, T. L., Brent, H. P. and Levin, A. V. (1999). Rapid improvement in the acuity of infants after visual input. Science, 286: 108–110.Google Scholar
Maurer, D., Lewis, T. L. and Mondloch, C. J. (2005). Missing sights: consequences for visual cognitive development. Trends Cogn. Sci., 9: 144–151.Google Scholar
Maurer, D. and Mondloch, C. (2011). Sensitive periods in face perception. In Calder, A., Rhodes, G., Haxby, J. and Johnson, M. (eds.), Handbook of Face Perception, pp. 779–797. Oxford: Oxford University Press.
Maurer, D., Mondloch, C. J. and Lewis, T. L. (2007). Sleeper effects. Dev. Sci., 10: 40–47.Google Scholar
Maurer, D., Mondloch, C. J., Robbins, R., Dywan, J. and Segalowitz, S. (2012). The influence of early experience on the later development of face expertise: lessons from cataract-reversal patients. Paper presented at the meeting of the International Conference on Infant Studies, Minneapolis.
Mayer, D. L., Beiser, A. S.,Warner, A. F., Pratt, E. M., Raye, K. N. and Lang, J. M. (1995). Monocular acuity norms for the Teller Acuity Cards between ages one month and four years. Invest. Ophthalmol. Vis. Sci., 36: 671–685.Google Scholar
Mondloch, C. J., Le Grand, R. and Maurer, D. (2003). Early visual experience is necessary for the development of some – but not all – aspects of face processing. In Pascalis, O. and Slater, A. (eds.), The Development of Face Processing in Infancy and Early Childhood, pp. 99–117. New York: Nova Science Publishers.
Mondloch, C. J., Lewis, T. L., Budreau, D. R., Maurer, D., Dannemiller, J. L., Stephens, B. R. and Kleiner-Gathercoal, K. A. (1999). Face perception during early infancy. Psychol. Sci., 10: 419–422.Google Scholar
Mondloch, C. J., Lewis, T. L., Maurer, D. and Levin, A. V. (1998). The effects of visual experience on face preferences during infancy. Developmental cognitive neuroscience technical report.
Mondloch, C. J., Robbins, R. and Maurer, D. (2010). Discrimination of facial features by adults, 10-year-olds, and cataract-reversal patients. Perception, 39: 184–194.Google Scholar
Movshon, J. A. and Kiorpes, L. (1993). Biological limits on visual development in primates. In Simons, K. (ed.), Early Visual Development: Normal and Abnormal, pp. 296–305. New York: Oxford University Press.
Pascual-Leone, A., Amedi, A., Fregni, F. and Merabet, L. B. (2005). The plastic human brain cortex. Ann. Rev., Neurosci., 28: 377–401.Google Scholar
Pasternak, T., Merigan, W. H. and Movshon, J. A. (1981). Motion mechanisms in strobereared cats: psychophysical and electrophysical measures. Acta Psychol. (Amst), 48: 321–332.Google Scholar
Pasternak, T., Schumer, R., Gizzi, M. and Movshon, J. (1985). Abolition of visual cortical direction selectivity affects visual behavior in cats. Exp. Brain Res., 61: 214–217.Google Scholar
Poirier, C., Collignon, O., De Volder, A. G., Renier, L., Vanlierde, A., Tranduy, D., Veraart, C. and Scheiber, C. (2006). Auditory motion perception activates visual motion areas in early blind subjects. Neuroimage, 31: 279–285.Google Scholar
Puce, A. and Perrett D. (2003). Electrophysiology and brain imaging of biological motion. Philos. Trans. R. Soc. Land. Biol. Sci.B, 358: 435–445.Google Scholar
Rhodes, G., Michie, P. T., Hughes, M. E. and Byatt, G. (2009). The fusiform face area and occipital face area show sensitivity to spatial relations in faces. Eur. J. Neurosci., 30: 721–733.Google Scholar
Robbins, R. A., Nishimura, M., Mondloch, C. J., Lewis, T. L. and Maurer, D. (2010). Deficits in sensitivity to spacing after early visual deprivation in humans: a comparison of human faces, monkey faces, and houses. Dev. Psychobiol., 52: 775–781.Google Scholar
Sale, A., Maya Vetencourt, J. F., Medini, P., Cenni, M. C., Baroncelli, L., De Pasquale, R. and Maffei, L. (2007). Environmental enrichment in adulthood promotes amblyopia recovery through a reduction of intracortical inhibition. Nature Neurosci., 10: 679–681.Google Scholar
Saygin, A. P. (2007). Superior temporal and premotor brain areas necessary for biological motion perception. Brain, 130: 2452–2461.Google Scholar
Servos, P., Osu, R., Santi, A. and Kawato, M. (2002). The neural substrates of biological motion perception: an fMRI study. Cereb. Cortex, 12: 772–782.Google Scholar
Sharma, N. and Cohen, L. (2012). Recovery of motor function after stroke. Dev. Psychobiol., 54: 254–262.Google Scholar
Simion, F., Regolin, L. and Bulf, H. (2008). A predisposition for biological motion in the newborn baby. Proc. Nat. Acad. Sci. USA, 105: 809–813.Google Scholar
Spector, F. and Maurer, D. (2009). Synesthesia: A new approach to understanding the development of perception. Dev. Psychol., 45: 175–189.Google Scholar
Sugita, Y. (2008). Face perception in monkeys reared with no exposure to faces. Proc. Nat. Acad. Sci. USA, 105: 394–398.Google Scholar
Taub, E. (2012). Parallels between the use of constraint-induced movement therapy to treat neurological motor disorders and amblyopia training. Dev. Psychobiol., 54: 274–292.Google Scholar
Thompson, B.,Mansouri, B., Koski, L. and Hess, R. F. (2008). Brain plasticity in the adult: modulation of function in amblyopia with rTMS. Curr. Biol., 18: 1067–1071.Google Scholar
Thompson, B., Mansouri, B., Koski, L. and Hess, R. F. (2012). From motor cortex to visual cortex: the application of non-invasive brain stimulation to amblyopia. Dev. Psychobiol., 54: 263–273.Google Scholar
Torborg, C. L. and Feller, M. B. (2005). Spontaneous patterned retinal activity and the refinement of retinal projections. Prog. Neurobiol., 76: 213–235.Google Scholar
Wagner, K. and Dobkins, K. R. (2011). Synaesthetic associations decrease during infancy. Psychol. Sci., 22: 1067–1072.Google Scholar
Wattam-Bell, J. (1996). Visual motion processing in one-month-old infants: habituation experiments. Vision Res., 36: 1679–1685.Google Scholar
Wattam-Bell, J.,Birtles, D., Nyström, P., von Hofsten, C.,Rosander, K.,Anker, S., Atkinson, J. and Braddick, O. (2010). Reorganization of global form and motion processing during human visual development. Curr. Biol., 20: 411–415.Google Scholar
Wilkinson, F., James, T. W.,Wilson, H. R., Gati, J., Menon, R. and Goodale, M. A. (2000). An fMRI study of the selective activation of human extrastriate form vision areas by radical and concentric gratings. Curr. Biol., 10: 1455–1458.Google Scholar
Zablocka, T. and Zernicki, B. (1996). Discrimination learning of grating orientation in visually deprived cats and the role of the superior colliculi. Behav. Neurosci., 110: 621–625.Google Scholar
Zablocka, T., Zernicki, B. and Kosmal, A. (1976). Visual cortex role in object discrimination in cats deprived of patter vision from birth. Acta Neurobiol., 36: 157–168.Google Scholar
Zernicki, B. (1979). Effects of binocular deprivation and specific experience in cats: behavioral, electrophysiological, and biochemical analyses. In Brazier, M. A. B. (ed.), Brain Mechanisms in Memory and Learning: From the Single Neuron to Man, pp. 179–195. New York: Raven Press.

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