Late blight, caused by the oomycete Phytophthora infestans, poses a significant challenge to organic tomato and potato production systems across the globe. To enhance education and outreach programming pertaining to tomato organic late blight management in Wisconsin, we sought to identify grower strategies and needs through an online survey conducted during spring 2018. Our findings demonstrated that organic growers emphasized crop diversity, crop rotation and soil health in their late blight management decisions. Grower concerns about biopesticides were identified and suggest that the use of input-based products within integrated management programs could be enhanced by further research on effectiveness and modes of actions. Additionally, stronger emphasis on oomycete pathogen biology and the significance of late blight as a community disease were identified as important areas of emphasis in the development of organic disease management education programming and resources that promote more effective cultural and chemical disease management strategies that adhere to the regulation and principles underlying the USDA National Organic Program. The integration of a live polling questionnaire conducted in winter 2019 allowed us to corroborate findings from the online survey and underscored the importance of two-way learning to enhance outreach efforts between Extension and organic growers in Wisconsin and the surrounding upper Midwestern states.

Based on probability theory, a methodology that allows diagnosing neonatal cardiac dynamics was previously developed; however, diagnostic applications of this method are required to validate it to the neonatal cardiac dynamics was conducted, allowing to differentiate normal from pathological dynamics. The hourly maximum and minimum heart rate values from 39 continuous and ambulatory electrocardiographic records with a minimum length of 21 hours were taken, from newborns between 0 and 10 days of life, 9 clinically within normality limits and 30 with cardiac pathologies. The probability of occurrence of heart rates in ranges of 5 beats/minute was calculated. The distributions of probability were analysed, and finally the diagnosis was determined by the physical-mathematical methodology. Then, a statistical validation of sensitivity, specificity, and diagnostic agreement was performed. Normal registries showed probability distributions with absent or minimal presence of heart rates of the ranges between 125 and 135 beats/minute, while the abnormal ones had values within these ranges, as well as absence or minimal presence of heart rates from 75 beats/minute to 85 beats/minute. The sensitivity and specificity were 100%, and the Kappa coefficient had a value of 1. Hereby, it is concluded that through an application of a physical–mathematical methodology of neonatal cardiac diagnosis, it is possible to differentiate normality from disease.

This commentary highlighted the background, take-home messages, and impacts of our 2007 British Journal of Nutrition paper entitled “Amino acids and immune function”. In 2003–2004, there was an outbreak of severe acute respiratory syndrome (SARS) caused by SARS coronavirus-1 (CoV-1) in Asian countries. By the mid-2000’s, clinical and experimental evidence indicated important roles for amino acids (AA) in improving innate and adaptive immunities in humans and animals. Based on our long-standing interest in AA metabolism and nutritional immunology, we decided to critically analyze advances in this nutritional field. Furthermore, we proposed a unified mechanism responsible for beneficial effects of AA and their products (including nitric oxide, glutathione, antibodies, and cytokines) on immune responses. We hoped that such integrated knowledge would be helpful for designing AA-based nutritional methods (e.g., supplementation with glutathione, arginine and glutamine) to prevent and treat SARS-like infectious diseases in the future. Our paper laid a framework for subsequent studies to quantify AA metabolism in intestinal bacteria, determine the effects of functional AA on cell-mediated and humoral immunities, and establish a much-needed database of AA composition in foodstuffs. Unexpectedly, COVID-19 (caused by SARS-CoV-2) emerged in December 2019 and has become one of the deadliest pandemics in history. Notably, glutathione, arginine and glutamine have now been exploited to effectively relieve severe respiratory symptoms of COVID-19 in affected patients. Functional AA (e.g., arginine, cysteine, glutamate, glutamine, glycine, taurine and tryptophan) and glutathione, which are all abundant in animal-sourced foodstuffs, are crucial for optimum immunity and health in humans and animals.

The morphological traits of alfalfa under acid soil conditions with different mobile aluminium (Al) concentrations were investigated. The study site was Vėžaičiai Branch of the Lithuanian Research Centre for Agriculture and Forestry, 55°70 N, 21°49 E. The experiment featuring the 30 most Al-tolerant alfalfa accessions (populations and cultivars), determined from laboratory trials was established on a Bathygleyic Dystric Retisol in 2018. In 2019 and 2020, the biological and morphological traits were evaluated: plant regrowth, plant height before flowering, wintering, leafiness, stem thickness, plant vigour, stem density, seed yield and resistance to spring black stem leaf spot. The resistance of alfalfa to mobile Al toxicity was determined using a filter-based screening method of selection cycles C1 and C2. The accessions grown in the soil with mobile Al (20.6–23.4 mg/kg) showed better tolerance to Al toxicity in the cycle C2. The hypocotyl tolerance index of these accessions was better at 8, 16, 32 and 64 mm AlCl3 concentrations in the cycle C2. The correlation analysis showed strong significant positive and negative relationships between the morphological traits. A cluster analysis showed that the accessions, grown in the soil with mobile Al (20.6–23.4 mg/kg) were the most resistant to Al toxicity in the cycle C2. These accessions produced a better seed yield and demonstrated lower values of morphological traits compared to cluster 2. Also, these accessions are considered as tolerant to mobile Al toxicity and might be used as donors in breeding for Al toxicity tolerance.

Do pandemics have lasting consequences for political behavior? The authors address this question by examining the consequences of the deadliest pandemic of the last millennium: the Black Death (1347–1351). They claim that pandemics can influence politics in the long run if the loss of life is high enough to increase the price of labor relative to other factors of production. When this occurs, labor-repressive regimes, such as serfdom, become untenable, which ultimately leads to the development of proto-democratic institutions and associated political cultures that shape modalities of political engagement for generations. The authors test their theory by tracing the consequences of the Black Death in German-speaking Central Europe. They find that areas hit hardest by that pandemic were more likely to adopt inclusive political institutions and equitable land ownership patterns, to exhibit electoral behavior indicating independence from landed elite influence during the transition to mass politics, and to have significantly lower vote shares for Hitler’s National Socialist Party in the Weimar Republic’s fateful 1930 and July 1932 elections.

In 2020, we are facing unprecedented times, and as some form of lockdown continues with no signs of ending feelings of hopelessness are completely natural and understandable. Unprecedented times does not mean that these current issues and struggles have never been faced by humanity before, however. The Spanish Flu which took place after World War One and the Black Death that was rampant in Asia and Europe in the 14th century quickly come to mind as examples of past pandemics, but these are only two examples of devastating diseases throughout human history. The Plague of Athens that was raging during the beginning of the Peloponnesian War in 430 BCE is another such example. Though removed from our current situation by many centuries, its symptoms and the effects it had on the population of Athens have been meticulously recorded by the general and historian Thucydides, giving us the opportunity to compare his account to our own experiences today. The disease may be different, and the image he portrays may be more violent and desperate than our own, but nonetheless we can see similarities in how these two separate societies have reacted to unforeseen hardships. In this comparison, we can come to understand at once our own good fortune at going through a pandemic with the support of modern technology and medicine as well as how universal our reactions are to this type of suffering, thereby making it natural rather than shameful. Humanity has faced a great deal of diversity before, and COVID-19 will likely prove to be no different.

The Northern Territories Protectorate and its people were located on the economic and political margins of Britain's Gold Coast Crown Colony (now Ghana) throughout the colonial period. The article examines how the region's peripherality allowed the Gold Coast Tsetse Control Department to carry out an extensive campaign of bush clearing and resettlement along northern river valleys from the 1930s to 1950s, with little supervision by the Gold Coast Medical Department or northern officials. Intended to control human and animal sleeping sickness and to meet the economic preferences of the colony's central administration, this campaign had the effect of greatly increasing the exposure of northern communities to another disease, onchocerciasis, causing widespread blindness and contributing to a serious public health crisis in the early independence era.