When bilinguals switch between their two languages, they often alternate between words whose formation rules in one language are different from the other (e.g., a noun-verb compound in one language may be a verb-noun compound in another language). In this study, we analyze behavioral performance and electrophysiological activity to examine the effects of morphological configuration on language control during production and comprehension. Chinese–English bilinguals completed a joint naming-listening task involving cued language switching. The findings showed differential effects of morphological configuration on language production and comprehension. In production, morphological configuration was processed sequentially, suggesting that bilingual production may be a combination of sequential processing and inhibition of morphological levels and language interference. In comprehension, however, bottom-up control processes appear to mask the influence of sequential processing on language switching. Together, these findings underscore differential functionalities of language control in speaking and listening.

We perform a two-dimensional numerical study on the thermal effect of porous media on global heat transport and flow structure in Rayleigh–Bénard (RB) convection, focusing on the role of thermal conductivity $\lambda$ of porous media, which ranges from $0.1$ to $50$ relative to the fluid. The simulation is carried out in a square RB cell with the Rayleigh number $Ra$ ranging from $10^7$ to $10^9$ and the Prandtl number $Pr$ fixed at $4.3$. The porosity of the system is fixed at $\phi =0.812$, with the porous media modelled by a set of randomly displayed circular obstacles. For a fixed $Ra$, the increase of conductivity shows a small effect on the total heat transfer, slightly depressing the Nusselt number. The limited influence comes from the small number of obstacles contacting with thermal plumes in the system as well as the counteraction of the increased plume area and the depressed plume strength. The study shows that the global heat transfer is insensitive to the conduction effect of separated porous media in the bulk region, which may have implications for industrial designs.

Cytochrome P450 proteins (CYPs) in insects can encode various detoxification enzymes and catabolize heterologous substances, conferring tolerance to insecticides. This study describes the identification of a P450 gene (CYP6BQ8) from Tribolium castaneum (Herbst) and investigation of its spatiotemporal expression profile and potential role in the detoxification of terpinen-4-ol, a component of plant essential oils. The developmental expression profile showed that TcCYP6BQ8 expression was relatively higher in early- and late-larval stages of T. castaneum compared with other developmental stages. Tissue expression profiles showed that TcCYP6BQ8 was mainly expressed in the head and integument of both larvae and adults. The expression profiling of TcCYP6BQ8 in developmental stages and tissues is closely related to the detoxification of heterologous substances. TcCYP6BQ8 expression was significantly induced after exposure to terpinen-4-ol, and RNA interference against TcCYP6BQ8 increased terpinen-4-ol-induced larval mortality from 47.78 to 66.67%. This indicates that TcCYP6BQ8 may be involved in T. castaneum's metabolism of terpinen-4-ol. Correlation investigation between the CYP6BQ8 gene and terpinen-4-ol resistance in T. castaneum revealed that the TcCYP6BQ8 gene was one of the factors behind T. castaneum's resistance to terpinen-4-ol. This discovery may provide a new theoretical foundation for future regulation of T. castaneum.

We study the translational and rotational dynamics of neutrally buoyant finite-size spheroids in hydrodynamic turbulence by means of fully resolved numerical simulations. We examine axisymmetric shapes, from oblate to prolate, and the particle volume dependences. We show that the accelerations and rotations experienced by non-spherical inertial-scale particles result from volume filtered fluid forces and torques, similar to spherical particles. However, the particle orientations carry signatures of preferential alignments with the surrounding flow structures, which are reflected in distinct axial and lateral fluctuations for accelerations and rotation rates. The randomization of orientations does not occur even for particles with volume-equivalent diameter size in the inertial range, here up to $60$ dissipative units ($\eta$) at Taylor-scale Reynolds number ${Re_{\lambda }=120}$. Additionally, we demonstrate that the role of fluid boundary layers around the particles cannot be neglected in reaching a quantitative understanding of particle statistical dynamics, as they affect the intensities of the angular velocities and the relative importance of tumbling with respect to spinning rotations. This study brings to the fore the importance of inertial-scale flow structures in homogeneous and isotropic turbulence and their impacts on the transport of neutrally buoyant bodies with sizes in the inertial range.

The present study investigated the effect of black soldier fly (Hermetia illucens) larvae meal (BSF) on haemolymph biochemical indicators, muscle metabolites as well as the lipid and glucose metabolism of Pacific white shrimp Litopenaeus vannamei. Four diets were formulated in which the control diet contained 25 % of fishmeal (FM) and 10 % (BSF10), 20 % (BSF20), and 30 % (BSF30) of FM protein were replaced with BSF. Four hundred and eighty shrimp (0·88 ± 0·00 g) were distributed to four groups of three replicates and fed for 7 weeks. Results showed that growth performance of shrimp fed BSF30 significantly decreased compared with those fed FM, but there was no significant difference in survival among groups. The whole shrimp crude lipid content, haemolymph TAG and total cholesterol were decreased with the increasing BSF inclusion. The results of metabolomics showed that the metabolite patterns of shrimp fed different diets were altered, with significant changes in metabolites related to lipid metabolism, glucose metabolism as well as TCA cycle. The mRNA expressions of hk, pfk, pk, pepck, ampk, mcd, cpt-1 and scd1 in hepatopancreas were downregulated in shrimp fed BSF30, but mRNA expression of acc1 was upregulated. Unlike BSF30, the mRNA expressions of fas, cpt-1, fbp and 6pgd in hepatopancreas were upregulated in shrimp fed BSF20. This study indicates that BSF20 diet promoted lipid synthesis and lipolysis, while BSF30 diet weakened β-oxidation and glycolysis as well as affected the unsaturated fatty acids synthesis, which may affect the growth performance and body composition of shrimp.

This research aims to investigate the salience of mothers’ emotional expressivity and its links with adolescents’ emotional wellbeing and expressivity in an urban society endorsing more individualism and a rural society ascribing to more collectivism. By comparing Chinese urban (N = 283, Mage = 14.13) and rural (N = 247, Mage = 14.09) adolescents, this research found that urban mothers’ expression of positive-dominant and positive-submissive emotions (PD and PS) were more common while expression of negative-dominant (ND) emotions was less common than rural mothers’. PD and PS had significant links with urban and rural adolescents’ increased emotional expressivity and self-esteem, however, only significantly related to urban adolescents’ decreased depression but not with rural adolescents’. ND had significant links with both urban and rural adolescents’ expression of negative emotions, however, only significantly correlated with urban adolescents’ less level of self-esteem and rural adolescents’ more expression of positive emotions. No significant difference was found in the salience of urban and rural mothers’ expression of negative-submissive (NS) emotions, which positively related to both urban and rural adolescents’ depression and emotional expressivity. Moreover, we found that adolescents’ emotional wellbeing (i.e., self-esteem and depression) mediated the relationship between mothers’ emotional expressivity and adolescents’ expressivity in both societies. Overall, the study findings document that the salience of mothers’ emotional expressivity and its relations with adolescents’ emotional adjustment differ between urban and rural societies.

We report on a three-dimensional direct numerical simulation study of flow structure and heat transport in the annular centrifugal Rayleigh–Bénard convection (ACRBC) system, with cold inner and hot outer cylinders corotating axially, for the Rayleigh number range $Ra \in [{10^6},{10^8}]$ and radius ratio range $\eta = {R_i}/{R_o} \in [0.3,0.9]$ ($R_i$ and $R_o$ are the radius of the inner and outer cylinders, respectively). This study focuses on the dependence of flow dynamics, heat transport and asymmetric mean temperature fields on the radius ratio $\eta$. For the inverse Rossby number $Ro^{-1} = 1$, as the Coriolis force balances inertial force, the flow is in the inertial regime. The mechanisms of zonal flow revolving in the prograde direction in this regime are attributed to the asymmetric movements of plumes and the different curvatures of the cylinders. The number of roll pairs is smaller than the circular roll hypothesis as the convection rolls are probably elongated by zonal flow. The physical mechanism of zonal flow is verified by the dependence of the drift frequency of the large-scale circulation (LSC) rolls and the space- and time-averaged azimuthal velocity on $\eta$. The larger $\eta$ is, the weaker the zonal flow becomes. We show that the heat transport efficiency increases with $\eta$. It is also found that the bulk temperature deviates from the arithmetic mean temperature and the deviation increases as $\eta$ decreases. This effect can be explained by a simple model that accounts for the curvature effects and the radially dependent centrifugal force in ACRBC.

Based on the fully compressible Navier–Stokes equations, the linear stability of thermal convection in rapidly rotating spherical shells of various radius ratios $\eta$ is studied for a wide range of Taylor number $Ta$, Prandtl number $Pr$ and the number of density scale height $N_\rho$. Besides the classical inertial mode and columnar mode, which are widely studied by the Boussinesq approximation and anelastic approximation, the quasi-geostrophic compressible mode is also identified in a wide range of $N_\rho$ and $Pr$ for all $\eta$ considered, and this mode mainly occurs in the convection with relatively small $Pr$ and large $N_\rho$. The instability processes are classified into five categories. In general, for the specified wavenumber $m$, the parameter space ($Pr, N_\rho$) of the fifth category, in which the base state loses stability via the quasi-geostrophic compressible mode and remains unstable, shrinks as $\eta$ increases. The asymptotic scaling behaviours of the critical Rayleigh numbers $Ra_c$ and corresponding wavenumbers $m_c$ to $Ta$ are found at different $\eta$ for the same instability mode. As $\eta$ increases, the flow stability is strengthened. Furthermore, the linearized perturbation equations and Reynolds–Orr equation are employed to quantitatively analyse the mechanical mechanisms and flow instability mechanisms of different modes. In the quasi-geostrophic compressible mode, the time-derivative term of disturbance density in the continuity equation and the diffusion term of disturbance temperature in the energy equation are found to be critical, while in the columnar and inertial modes, they can generally be ignored. Because the time-derivative term of the disturbance density in the continuity equation cannot be ignored, the anelastic approximation fails to capture the instability mode in the small-$Pr$ and large-$N_\rho$ system, where convection onset is dominated by the quasi-geostrophic compressible mode. However, all the modes are primarily governed by the balance between the Coriolis force and the pressure gradient, based on the momentum equation. Physically, the most important difference between the quasi-geostrophic compressible mode and the columnar mode is the role played by the disturbance pressure. The disturbance pressure performs negative work for the former mode, which appears to stabilize the flow, while it destabilizes the flow for the latter mode. As $\eta$ increases, in the former mode the relative work performed by the disturbance pressure increases and in the latter mode decreases.

Almost all hospitals are equipped with air-conditioning systems to provide a comfortable environment for patients and staff. However, the accumulation of dust and moisture within these systems increases the risk of transmission of microbes and have on occasion been associated with outbreaks of infection. Nevertheless, the impact of air-conditioning on the transmission of microorganisms leading to infection remains largely uncertain. We conducted a scoping review to screen systematically the evidence for such an association in the face of the coronavirus disease 2019 epidemic. PubMed, Embase and Web of Science databases were explored for relevant studies addressing microbial contamination of the air, their transmission and association with infectious diseases. The review process yielded 21 publications, 17 of which were cross-sectional studies, three were cohort studies and one case−control study. Our analysis showed that, compared with naturally ventilated areas, microbial loads were significantly lower in air-conditioned areas, but the incidence of infections increased if not properly managed. The use of high-efficiency particulate air (HEPA) filtration not only decreased transmission of airborne bioaerosols and various microorganisms, but also reduced the risk of infections. By contrast, contaminated air-conditioning systems in hospital rooms were associated with a higher risk of patient infection. Cleaning and maintenance of such systems to recommended standards should be performed regularly and where appropriate, the installation of HEPA filters can effectively mitigate microbial contamination in the public areas of hospitals.

This study deploys RTK-GNSS in 2012, TLS in 2015 and UAV in 2018 to monitor the changes of Urumqi Glacier No. 1 (UG1), eastern Tien Shan, and analyzes the feasibility of three technologies in monitoring the mountain glaciers. DEM differencing shows that UG1 has experienced a pronounced thinning and mass loss for the period of 2012–18. The glacier surface elevation change of −0.83 ± 0.57 m w.e. a−1 has been recorded for 2012–15, whereas the changes of glacier tongue surface elevation in 2015–18 and 2012–18 were −2.03 ± 0.95 and −1.34 ± 0.88 m w.e. a−1, respectively. The glacier area shrunk by 0.07 ± 0.07 × 10−3 km2 and the terminus retreat rate was 6.28 ± 0.83 m a−1 during 2012–18. The good agreement between the glaciological and geodetic specific mass-balances is promising, showing the combination of the three technologies is suitable to monitor glacier mass change. We recommend application of the three technologies to assess each other in different locations of the glacier, e.g. RTK-GNSS base stations, ground control points, glacier tongue and terminus, in order to avoid the inherent limitations of each technology and to provide reliable data for the future studies of mountain glacier changes in western China.

We report a numerical study of Rayleigh–Bénard convection through random porous media using pore-scale modelling, focusing on the Lagrangian dynamics of fluid particles and heat transfer for varied porosities $\phi$. Due to the interaction between the porous medium and the coherent flow structures, the flow is found to be highly heterogeneous, consisting of convection channels with strong flow strength and stagnant regions with low velocities. The modifications of flow field due to porous structure have a significant influence on the dynamics of fluid particles. Evaluation of the particle displacement along the trajectory reveals the emergence of anomalous transport for long times as $\phi$ is decreased, which is associated with the long-time correlation of Lagrangian velocity of the fluid. As porosity is decreased, the cross-correlation between the vertical velocity and temperature fluctuation is enhanced, which reveals a mechanism to enhance the heat transfer in porous-media convection.

Despite the numerous challenges of ageing in a foreign land, many older immigrants are fairly resilient and report experiencing good wellbeing. The key question that the present paper addresses is how this is achieved. Drawing on frameworks from cross-cultural and social identity literatures, the present study proposes and tests a model of serial multiple mediation that identifies possible mechanisms supporting the wellbeing of older immigrants who have resided in the host country for some time. In this model, it is predicted that new group memberships acquired post-migration enable access to social support that in turn provides the basis for perceived integration, which enhances wellbeing. This model was tested in a survey study with 102 older people, whose mean age was 80.3 years and who had migrated to Australia from Asian, European, and Central and South American countries on average 36 years previously. The survey assessed cultural identity, social group memberships acquired post-migration, perceived social support, perceived integration and wellbeing. Results supported the hypothesised model, indicating that joining new heritage culture and wider groups in Australia post-migration provided a platform for social support and integration, which enhanced life satisfaction and reduced loneliness. The implications of these findings for theory and adapting successfully to both migration and ageing are discussed.

Colour is widely utilised as a visual coding system in visual search, but its application under vibration conditions (e.g., in various vehicles) has not been fully explored. This study was designed to examine the effect of colour combinations on performance of visual search tasks conducted in vibration conditions. Forty-eight university students participated in an experiment where they were required to identify target type and location under 24 colour combinations (half in negative polarity and half in positive polarity) and three vibration conditions (static, low, and high). The findings showed that vibration did not significantly affect performance, perceptions, or physiological aspects. Colour combination significantly affected response time, and the participants preferred colour combinations that had the potential to produce better performance. Colour combinations with negative polarity (e.g., yellow on black and white on black) are recommended for presenting search interfaces. These findings are of importance in human–computer interface designs for information display under vibration conditions.

Shifts in the maternal gut microbiota have been implicated in the development of gestational diabetes mellitus (GDM). Understanding the interaction between gut microbiota and host glucose metabolism will provide a new target of prediction and treatment. In this nested case-control study, we aimed to investigate the causal effects of gut microbiota from GDM patients on the glucose metabolism of germ-free (GF) mice. Stool and peripheral blood samples, as well as clinical information, were collected from 45 GDM patients and 45 healthy controls (matched by age and prepregnancy body mass index (BMI)) in the first and second trimester. Gut microbiota profiles were explored by next-generation sequencing of the 16S rRNA gene, and inflammatory factors in peripheral blood were analyzed by enzyme-linked immunosorbent assay. Fecal samples from GDM and non-GDM donors were transferred to GF mice. The gut microbiota of women with GDM showed reduced richness, specifically decreased Bacteroides and Akkermansia, as well as increased Faecalibacterium. The relative abundance of Akkermansia was negatively associated with blood glucose levels, and the relative abundance of Faecalibacterium was positively related to inflammatory factor concentrations. The transfer of fecal microbiota from GDM and non-GDM donors to GF mice resulted in different gut microbiota colonization patterns, and hyperglycemia was induced in mice that received GDM donor microbiota. These results suggested that the shifting pattern of gut microbiota in GDM patients contributed to disease pathogenesis.

This study aimed to identify clinical features for prognosing mortality risk using machine-learning methods in patients with coronavirus disease 2019 (COVID-19). A retrospective study of the inpatients with COVID-19 admitted from 15 January to 15 March 2020 in Wuhan is reported. The data of symptoms, comorbidity, demographic, vital sign, CT scans results and laboratory test results on admission were collected. Machine-learning methods (Random Forest and XGboost) were used to rank clinical features for mortality risk. Multivariate logistic regression models were applied to identify clinical features with statistical significance. The predictors of mortality were lactate dehydrogenase (LDH), C-reactive protein (CRP) and age based on 500 bootstrapped samples. A multivariate logistic regression model was formed to predict mortality 292 in-sample patients with area under the receiver operating characteristics (AUROC) of 0.9521, which was better than CURB-65 (AUROC of 0.8501) and the machine-learning-based model (AUROC of 0.4530). An out-sample data set of 13 patients was further tested to show our model (AUROC of 0.6061) was also better than CURB-65 (AUROC of 0.4608) and the machine-learning-based model (AUROC of 0.2292). LDH, CRP and age can be used to identify severe patients with COVID-19 on hospital admission.

Six acidic dykes were discovered surrounding the Laiziling pluton, Xianghualing area, in the western Cathaysia Block, South China. A number of captured zircons are found in two of these acidic dykes. By detailed U–Pb dating, Lu–Hf isotopes and trace-element analysis, we find that these zircons have ages clustered at c. 2.5 Ga. Two acidic dyke samples yielded upper intersection point 206U/238Pb ages of 2505 ± 42 Ma and 2533 ± 22 Ma, and weighted mean 207Pb/206Pb ages of 2500 ± 30 Ma and 2535 ± 16 Ma. The majority of these zircons have high (Sm/La)N, Th/U and low Ce/Ce* ratios, indicating a magmatic origin, but some grains were altered by later hydrothermal fluid. Additionally, the magmatic zircons have high Y, U, heavy rare earth element, Nb and Ta contents, indicating that their host rocks were mainly mafic rocks or trondhjemite–tonalite–granodiorite rock series. Equally, their moderate Y, Yb, Th, Gd and Er contents also indicate that a mafic source formed in a continental volcanic-arc environment. These zircons have positive ϵHf(t) values (2.5–6.9) close to zircons from the depleted mantle, with TDM (2565–2741 Ma) and TDM2 (2608–2864 Ma) ages close to their formation ages, indicating that these zircons originated directly from depleted mantle magma, or juvenile crust derived from the depleted mantle in a very short period. We therefore infer that the Cathaysia Block experienced a crustal growth event at c. 2.5 Ga.

Giant chickweed [Myosoton aquaticum (L.) Moench], a troublesome broadleaf weed species, is widespread in winter wheat (Triticum aestivum L.) fields in China. However, limited information is available on its germination and seedling emergence ecology. Thus, three M. aquaticum populations (JS, HN, and AH) from different geographic regions were studied under laboratory conditions to determine the effects of different environmental factors on germination or seedling emergence. The seeds germinated at a relatively wide constant temperature range of 5 to 25 C; however, the optimal temperature for germination varied among the populations. Compared with constant temperatures, fluctuating temperatures with the same mean significantly improved the final germination of all populations. Light was not required for germination. The seeds germinated under a wide pH range of 3 to 10, and the optimum pH was 6 to 7, with a final germination percentage of 81% to 95%. The seeds of all populations showed similar sensitivities to osmotic potential and similar high tolerances of saline conditions. The seedling emergence of all populations decreased with increasing burial depth, and no emergence was observed when the seeds were buried more than 3 cm, but the AH population showed higher sensitivity to burial depth than the others. The results generated from this study will contribute to the development of integrated M. aquaticum management strategies for winter wheat fields in China, and deep plowing and late sowing of autumn-sown wheat are suggested for managing M. aquaticum, as it showed lower germination at a low temperature and under relatively deep burial.

The Wulian complex is located on the northern margin of the Sulu orogenic belt, and was formed by collision between the North China Craton (NCC) to the north and South China Craton (SCC) to the south. It consists of the metasedimentary Wulian Group, gneissic granite and meta-diorite. The U–Pb analyses for the detrital zircons from the Wulian Group exhibit one predominant age population of 2600–2400 Ma with a peak at c. 2.5 Ga and several secondary age populations of > 3000, 3000–2800, 2800–2600, 2200–2000, 1900–1800, 1500–1300 and 1250–950 Ma; some metamorphic zircons have metamorphic ages of c. 2.7, 2.55–2.45, 2.1–2.0 and 1.95–1.80 Ga, which are consistent with magmatic-metamorphic events in the SCC. Additionally, the Wulian Group was intruded by the gneissic granite and meta-diorite at c. 0.76 Ga, attributed to Neoproterozoic syn-rifting bimodal magmatic activity in the SCC and derived from partial melting of Archaean continental crust and depleted mantle, respectively. The Wulian Group therefore has tectonic affinity to the SCC and was mainly sourced from the SCC. The detrital zircons have positive and negative ϵHf(t) values, indicating that their source rocks were derived from reworking of both ancient and juvenile crustal rocks. The major early Precambrian crustal growth took place during c. 3.4–2.5 Ga with a dominant peak at 2.96 Ga and several secondary peaks at 3.27, 2.74 and 2.52 Ga. The two oldest zircons with ages of 3307 and 3347 Ma record the recycling of ancient continental crust (> 3.35 Ga) and crustal growth prior to c. 3.95 Ga in the SCC.