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Chapter 33 - Myofascial Pain Syndrome

from Part VI - Misc

Published online by Cambridge University Press:  01 December 2023

Omar Viswanath
Affiliation:
Creighton University, Omaha
Ivan Urits
Affiliation:
Southcoast Brain & Spine Center, Wareham
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Summary

Myofascial pain syndrome (MPS) is characterized by localized, taut regions comprising of skeletal muscle and fascia, termed trigger points and is an increasingly prevalent complaint. Pharmacologic interventions with evidence to support their use in MPS include muscle relaxants such as benzodiazepines, tizanidine, and cyclobenzaprine; TCAs; topical agents such as diclofenac gel and lidocaine patches; and injection therapy of botulinum toxin or lidocaine. MPS is poorly understood and remains a challenging condition to treat. Nonpharmacologic treatment modalities such as acupuncture, massage, transcutaneous electrical stimulation, and interferential current therapy may offer relief to some patients with MPS. Additional studies are warranted to get a better understanding of managing myofascial pain.

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Publisher: Cambridge University Press
Print publication year: 2023

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References

Wheeler, AH, Carolina, N. Myofascial pain disorders: Theory to therapy. Drugs. 2004;64(1):4562.CrossRefGoogle ScholarPubMed
Harden, RN, Bruehl, SP, Gass, S, Niemiec, C, Barbick, B. Signs and symptoms of the myofascial pain syndrome: A national survey of pain management providers. Clin J Pain. 2000;16(1):6472.CrossRefGoogle ScholarPubMed
Fleckenstein, J, Zaps, D, Rüger, LJ et al. Discrepancy between prevalence and perceived effectiveness of treatment methods in myofascial pain syndrome: Results of a cross-sectional, nationwide survey. BMC Musculoskelet Disord. 2010;11:32. doi: 10.1186/1471-2474-11-32.CrossRefGoogle ScholarPubMed
Gerwin, RD. Classification, epidemiology, and natural history of myofascial pain syndrome. Curr Pain Headache Rep. 2001;5(5):412420.CrossRefGoogle ScholarPubMed
Vázquez-Delgado, E, Cascos-Romero, J, Gay-Escoda, C. Myofascial pain syndrome associated with trigger points: A literature review. (I): Epidemiology, clinical treatment and etiopathogeny. Med Oral Patol Oral Cir Bucal. 2009;14(10):e494e498.CrossRefGoogle ScholarPubMed
Lin, WC, Shen, CC, Tsai, SJ, Yang, AC. Increased risk of myofascial pain syndrome among patients with insomnia. Pain Med (United States). 2017;18(8):15571565.CrossRefGoogle ScholarPubMed
Bartley, J, Reid, D, Morton, RP. Prevalence of vitamin D deficiency among patients attending a general otolaryngology clinic in South Auckland. Ann Otol Rhinol Laryngol. 2009;118(5):326328.CrossRefGoogle ScholarPubMed
Vidaković, B, Uljanić, I, Perić, B, Grgurević, J, Sonicki, Z. Myofascial pain of the head and neck among Croatian war veterans treated for depression and posttraumatic stress disorder. Psychiatr Danub. 2016;28(1):7376.Google ScholarPubMed
Brodsky, M, Spritzer, K, Hays, RD, Hui, KK. Change in health-related quality-of-life at group and individual levels over time in patients treated for chronic myofascial neck pain. J Evidence-Based Complement Altern Med. 2017;22(3):365368.CrossRefGoogle ScholarPubMed
Celik, D, Mutlu, EK. Clinical implication of latent myofascial trigger point topical collection on myofascial pain. Curr Pain Headache Rep. 2013;17(8):353. doi: 10.1007/s11916-013-0353-8. PMID: 23801006.CrossRefGoogle Scholar
Money, S. Pathophysiology of trigger points in myofascial pain syndrome. J Pain Palliat Care Pharmacother. 2017;31(2):158159.CrossRefGoogle ScholarPubMed
Baldry, P. Management of myofascial trigger point pain. Acupunct Med. 2002;20(1):210.CrossRefGoogle ScholarPubMed
Hong, CZ, Simons, DG. Pathophysiologic and electrophysiologic mechanisms of myofascial trigger points. Arch Phys Med Rehabil. 1998;79(7):863872.CrossRefGoogle ScholarPubMed
Simons, DG. Clinical and etiological update of myofascial pain from trigger points. J Musculoskelet Pain. 1996;4(1–2):93122.CrossRefGoogle Scholar
Juan, FJ. Use of botulinum toxin-A for musculoskeletal pain in patients with whiplash associated disorders [ISRCTN68653575]. BMC Musculoskelet Disord. 2004;5(1):5. doi: 10.1186/1471-2474-5-5. PMID: 15018625; PMCID: PMC356919.CrossRefGoogle ScholarPubMed
Acquadro, MA, Borodic, GE. Treatment of myofascial pain with botulinum A toxin. Anesthesiology. 1994;80(3):705706.CrossRefGoogle ScholarPubMed
Zhou, JY, Wang, D. An update on botulinum toxin A injections of trigger points for myofascial pain. Curr Pain Headache Rep. 2014;18(1):386. doi: 10.1007/s11916-013-0386-z. PMID: 24338700.CrossRefGoogle ScholarPubMed
Ge, H-Y, Fernández-de-Las-Peñas, C, Yue, S-W. Myofascial trigger points: Spontaneous electrical activity and its consequences for pain induction and propagation. Chin Med. 2011;6:13. doi: 10.1186/1749-8546-6-13. PMID: 21439050; PMCID: PMC3070691.CrossRefGoogle ScholarPubMed
Simons, DG, Dexter, JR. Comparison of local twitch responses elicited by palpitation and needling of myofascial trigger points. J Musculoskelet Pain. 1995;3(1):4961.CrossRefGoogle Scholar
Bengtsson, A, Henriksson, KG, Larsson, J. Reduced high-energy phosphate levels in the painful muscles of patients with primary fibromyalgia. Arthritis Rheum. 1986;29(7):817821.CrossRefGoogle ScholarPubMed
Jafri, MS. Mechanisms of myofascial pain. Int Sch Res Not. 2014;2014:523924. oi: 10.1155/2014/523924. PMID: 25574501; PMCID: PMC4285362.Google ScholarPubMed
Graff-Radford, SB. Myofascial pain: Diagnosis and management. Curr Pain Headache Rep. 2004;8(6):463467.CrossRefGoogle ScholarPubMed
Thibaut, A, Zeng, D, Caumo, W, Liu, J, Fregni, F. Corticospinal excitability as a biomarker of myofascial pain syndrome. PAIN Rep. 2017;2(3):e594. doi: 10.1097/PR9.0000000000000594. PMID: 29392210; PMCID: PMC5741300.CrossRefGoogle ScholarPubMed
Chen, Q, Basford, J, An, K-N. Ability of magnetic resonance elastography to assess taut bands. Clin Biomech (Bristol, Avon). 2008;23(5):623629.CrossRefGoogle ScholarPubMed
Fricton, J. Myofascial pain. Oral Maxillofac Surg Clin North Am. 2016;28(3):289311.CrossRefGoogle ScholarPubMed
Bonder, JH, Chi, M, Rispoli, L. Myofascial pelvic pain and related disorders. Phys Med Rehabil Clin North Am. 2017;28(3):501515.CrossRefGoogle ScholarPubMed
Do, TP, Heldarskard, GF, Kolding, LT, Hvedstrup, J, Schytz, HW. Myofascial trigger points in migraine and tension-type headache. J Headache Pain. 2018;19(1):84. doi: 10.1186/s10194-018-0913-8. PMID: 30203398; PMCID: PMC6134706.CrossRefGoogle ScholarPubMed
Palacios-Ceña, M, Wang, K, Castaldo, M et al. Trigger points are associated with widespread pressure pain sensitivity in people with tension-type headache. Cephalalgia. 2018;38(2):237245.CrossRefGoogle ScholarPubMed
Cambron, J. A new era for the Journal of Bodywork and Movement Therapies. J Bodyw Mov Ther. 2019;23(1):12.CrossRefGoogle ScholarPubMed
Bajaj, P, Bajaj, P, Graven-Nielsen, T, Arendt-Nielsen, L. Trigger points in patients with lower limb osteoarthritis. J Musculoskelet Pain. 2001;9(3):1733.CrossRefGoogle Scholar
Henry, R, Cahill, CM, Wood, G et al. Myofascial pain in patients waitlisted for total knee arthroplasty. Pain Res Manag. 2012; 17(5):321327.CrossRefGoogle ScholarPubMed
Peral-Cagigal, B, Pérez-Villar, Á, Redondo-González, L-M et al. Temporal headache and jaw claudication may be the key for the diagnosis of giant cell arteritis. Med Oral Patol Oral Cir Bucal. 2018;23(3):e290e294.Google ScholarPubMed
Chiarotto, A, Clijsen, R, Fernandez-De-Las-Penas, C, Barbero, M. Prevalence of myofascial trigger points in spinal disorders: A systematic review and meta-analysis. Presented as an abstract and poster to the World Confederation of Physical Therapy Congress, May 1–4, 2015, Singapore. Arch Phys Med Rehabil. 2016;97(2):316337.CrossRefGoogle ScholarPubMed
Bourgaize, S, Newton, G, Kumbhare, D, Srbely, J. A comparison of the clinical manifestation and pathophysiology of myofascial pain syndrome and fibromyalgia: Implications for differential diagnosis and management. J Can Chiropr Assoc. 2018;62(1):2641.Google ScholarPubMed
Ajimsha, MS, Al-mudahka, NR. Effectiveness of myofascial release: Systematic review of randomized controlled trials. J Bodyw Mov Ther. 2015;19(1):102112.CrossRefGoogle ScholarPubMed
Laimi, K, Mäkilä, A, Bärlund, E et al. Effectiveness of myofascial release in treatment of chronic musculoskeletal pain: A systematic review. Clin Rehabil. 2018;32(4):440450.CrossRefGoogle ScholarPubMed
Ajimsha, MS, Daniel, B, Chithra, S. Effectiveness of myofascial release in the management of chronic low back pain in nursing professionals. J Bodyw Mov Ther. 2014;18(2):273281.CrossRefGoogle ScholarPubMed
Kalichman, L, Ben David, C. Effect of self-myofascial release on myofascial pain, muscle flexibility, and strength: A narrative review. J Bodyw Mov Ther. 2017;21(2):446451.CrossRefGoogle ScholarPubMed
Beardsley, C, Škarabot, J. Effects of self-myofascial release: A systematic review. J Bodyw Mov Ther. 2015;19(4):747758.CrossRefGoogle ScholarPubMed
Liu, L, Huang, QM, Liu, QG et al. Evidence for dry needling in the management of myofascial trigger points associated with low back pain: A systematic review and meta-analysis. Arch Phys Med Rehabil. 2018;99(1):144152.CrossRefGoogle ScholarPubMed
Espejo-Antúnez, L, Tejeda, JFH, Albornoz-Cabello, M et al. Dry needling in the management of myofascial trigger points: A systematic review of randomized controlled trials. Complement Ther Med. 2017;33:4657.CrossRefGoogle ScholarPubMed
Rodríguez-Mansilla, J, Gonzalez-Sanchez, B. Effectiveness of dry needling on reducing pain intensity in patients with myofascial pain syndrome: A meta-analysis. J Tradit Chinese Med. 2016;36(1):1–13. doi: 10.1016/s0254-6272(16)30001-2. PMID: 26946612.CrossRefGoogle ScholarPubMed
Furlan, AD, van Tulder, M, Cherkin, D et al. Acupuncture and dry-needling for low back pain: An updated systematic review within the framework of the cochrane collaboration. Spine. 2005;30(8):944963. doi: 10.1097/01.brs.0000158941.21571.01. PMID: 15834340.CrossRefGoogle ScholarPubMed
Abbaszadeh-Amirdehi, M, Nakhostin Ansari, N, Naghdi, S, Olyaei, G. Neurophysiological and clinical effects of dry needling in patients with upper trapezius myofascial trigger points. J Bodyw Mov Ther. 2017;21(1):4852.CrossRefGoogle ScholarPubMed
Gerber, LH, Sikdar, S, Aredo, JV et al. Beneficial effects of dry needling for treatment of chronic myofascial pain persist for 6 weeks after treatment completion. PM&R. 2017;9(2):105112.Google ScholarPubMed
Wang, R, Li, X, Zhou, S et al. Manual acupuncture for myofascial pain syndrome: A systematic review and meta-analysis. Acupunct Med. 2017;35(4):241250.CrossRefGoogle ScholarPubMed
Mayo Clinic. Acupuncture. 2019. pp. 25.Google Scholar
Chou, LW, Hsieh, YL, Chen, HS et al. Remote therapeutic effectiveness of acupuncture in treating myofascial trigger point of the upper trapezius muscle. Am J Phys Med Rehabil. 2011;90(12):10361049.CrossRefGoogle ScholarPubMed
Hsieh, Y, Hong, C, Liu, S, Chou, L. Acupuncture at distant myofascial trigger spots enhances endogenous opioids in rabbits: A possible mechanism for managing myofascial pain. Acupunct Med. 2016;34(4):302309.CrossRefGoogle Scholar
Fan, A, He, H. Dry needling is acupuncture. Acupunct Med. 2016;34(3):241. doi: 10.1136/acupmed-2015-011010. Epub 2015 Dec 15. PMID: 26672062.CrossRefGoogle ScholarPubMed
Gibson, W, Bm, W, Meads, C, Mj, C, Ne, OC. Transcutaneous electrical nerve stimulation (TENS) for chronic pain: An overview of cochrane reviews (Review). Cochrane Database Syst Rev. 2019;2(2):CD011890. doi: 10.1002/14651858.CD011890.pub2.Google ScholarPubMed
Sluka, KA, Bjordal, JM, Marchand, S, Rakel, BA. What makes transcutaneous electrical nerve stimulation work? Making sense of the mixed results in the clinical literature. Phys Ther. 2013;93(10):13971402.CrossRefGoogle ScholarPubMed
Rodríguez-Fernández, ÁL, Garrido-Santofimi, V, Güeita-Rodríguez, J, Fernández-de-las-Peñas, C. Effects of burst-type transcutaneous electrical nerve stimulation on cervical range of motion and latent myofascial trigger point pain sensitivity. Arch Phys Med Rehabil. 2011;92(9):13531358.CrossRefGoogle ScholarPubMed
Gemmell, H, Hilland, A. Immediate effect of electric point stimulation (TENS) in treating latent upper trapezius trigger points: A double blind randomised. J Bodyw Mov Ther. 2011;15(3):348354.CrossRefGoogle ScholarPubMed
Fuentes, JP, Olivo, SA, Magee, DJ, Gross, DP. Effectiveness of interferential current therapy in the management of musculoskeletal pain: A systematic review and meta-analysis. Phys Ther. 2010;90(9):12191238.CrossRefGoogle ScholarPubMed
Albornoz-Cabello, M, Maya-Martín, J, Domínguez-Maldonado, G, Espejo-Antúnez, L, Heredia-rizo, AM. Effect of interferential current therapy on pain perception and disability level in subjects with chronic low back pain: A randomized controlled trial. 2017;31(2):242249. doi: 10.1177/0269215516639653. Epub 2016 Jul 10. PMID: 26975312.Google Scholar
Cadena de Almeida, C, Maldaner de Silva, VZ, Cipriano Junior, G, Eloin Liebano, R, Joao Luiz, QD. Transcutaneous electrical nerve stimulation and interferential current demonstrate similar effects in relieving acute and chronic pain: A systematic review with meta-analysis. Brazilian J Phys Ther. 2018;22(5):347354.CrossRefGoogle Scholar
Dissanayaka, T, Pallegama, R, Suraweera, H, Johnson, MI, Kariyawasam, AP. Comparison of the effectiveness of transcutaneous electrical nerve stimulation and interferential therapy on the upper trapezius in myofascial pain syndrome. Am J Phys Med Rehabil. 2016;95(9):663672.CrossRefGoogle Scholar
Giggins, OM, Persson, UM, Caulfield, B. Biofeedback in rehabilitation. J Neuroeng Rehabil. 2013;10(1):60. doi: 10.1186/1743-0003-10-60. PMID: 23777436; PMCID: PMC3687555.CrossRefGoogle ScholarPubMed
Srinivasan, AK, Kaye, JD, Moldwin, R. Myofascial dysfunction associated with chronic pelvic floor pain: Management strategies. Curr Pain Headache Rep. 2007;11(5):359364. doi: 10.1007/s11916-007-0218-0. PMID: 17894926.CrossRefGoogle ScholarPubMed
Nestoriuc, Y, Martin, A, Rief, W, Andrasik, F. Biofeedback treatment for headache disorders: A comprehensive efficacy review. Appl Psychophysiol Biofeedback. 2008;33(3):125140.CrossRefGoogle ScholarPubMed
Whelton, A. Renal and related cardiovascular effects of conventional and COX-2-specific NSAIDs and non-NSAID analgesics. Am J Ther. 2000;7(2):6374.CrossRefGoogle ScholarPubMed
Laine, L. Gastrointestinal effects of NSAIDs and coxibs. J Pain Symptom Manage. 2003;25(2):3240.CrossRefGoogle ScholarPubMed
Rainsford, K. Profile and mechanisms of gastrointestinal and other side effects of nonsteroidal anti-inflammatory drugs (NSAIDs). Am J Med. 1999;107(6):2735.CrossRefGoogle ScholarPubMed
Cashman, JN. The mechanisms of action of NSAIDs in analgesia. Drugs. 1996;52(Suppl 5):1323.CrossRefGoogle ScholarPubMed
Hsieh, L-F, Hong, C-Z, Chern, S-H, Chen, C-C. Efficacy and side effects of diclofenac patch in treatment of patients with myofascial pain syndrome of the upper trapezius. J Pain Symptom Manage. 2010;39(1):116125.CrossRefGoogle ScholarPubMed
Plesh, O, Curtis, D, Levine, J, McCall, WD. Amitriptyline treatment of chronic pain in patients with temporomandibular disorders. J Oral Rehabil. 2000;27(10):834841.CrossRefGoogle ScholarPubMed
Huang-Lionnet, JH, Hameed, H, Cohen, SP. Pharmacologic management of myofascial pain. In Essentials of pain medicine. 4th ed. 2018. pp. 475484. doi: 10.1016/B978-0-323-40196-8.00053-X.CrossRefGoogle Scholar
Gallagher, RM. Management of neuropathic pain: Translating mechanistic advances and evidence-based research into clinical practice. Clin J Pain. 2006;22(Suppl 1):S2S8.CrossRefGoogle ScholarPubMed
Obata, H. Analgesic mechanisms of antidepressants for neuropathic pain. Int J Mol Sci. 2017;18(11): 2483. doi: 10.3390/ijms18112483.CrossRefGoogle ScholarPubMed
Bendtsen, L, Jensen, R. Amitriptyline reduces myofascial tenderness in patients with chronic tension-type headache. Cephalalgia. 2000;20(6):603610.CrossRefGoogle ScholarPubMed
Haviv, Y, Rettman, A, Aframian, D, Sharav, Y, Benoliel, R. Myofascial pain: An open study on the pharmacotherapeutic response to stepped treatment with tricyclic antidepressants and gabapentin. J Oral Facial Pain Headache. 2015;29(2):144151.CrossRefGoogle Scholar
Haviv, Y, Zini, A, Sharav, Y, Almoznino, G, Benoliel, R. Nortriptyline compared to amitriptyline for the treatment of persistent masticatory myofascial pain. J Oral Facial Pain Headache. 2018;33(1):713. doi: 10.11607/ofph.1886.CrossRefGoogle ScholarPubMed
Czarnetzki, C, Elia, N, Lysakowski, C et al. Dexamethasone and risk of nausea and vomiting and postoperative bleeding after tonsillectomy in children. JAMA. 2008;300(22):26212630. doi: 10.1001/jama.2008.794. PMID: 19066382.CrossRefGoogle ScholarPubMed
Annaswamy, TM, De Luigi, AJ, O’Neill, BJ, Keole, N, Berbrayer, D. Emerging concepts in the treatment of myofascial pain: A review of medications, modalities, and needle-based interventions. PM&R. 2011;3(10):940961.Google Scholar
Heir, GM. The efficacy of pharmacologic treatment of temporomandibular disorders. Oral Maxillofac Surg Clin North Am. 2018;30(3):279285.CrossRefGoogle ScholarPubMed
McNeill, C. Management of temporomandibular disorders: concepts and controversies. J Prosthet Dent. 1997;77(5):510522. doi: 10.1016/s0022-3913(97)70145-8. PMID: 9151272.CrossRefGoogle Scholar
Loveless, MS, Fry, AL. Pharmacologic therapies in musculoskeletal conditions. Med Clin North Am. 2016;100(4):869890.CrossRefGoogle ScholarPubMed
Häggman-Henrikson, B, Alstergren, P, Davidson, T et al. Pharmacological treatment of oro-facial pain: Health technology assessment including a systematic review with network meta-analysis. J Oral Rehabil. 2017;44(10):800826.CrossRefGoogle ScholarPubMed
Herman, CR, Schiffman, EL, Look, JO, Rindal, DB. The effectiveness of adding pharmacologic treatment with clonazepam or cyclobenzaprine to patient education and self-care for the treatment of jaw pain upon awakening: A randomized clinical trial. J Orofac Pain. 2002;16(1):6470.Google ScholarPubMed
Fishbain, DA, Cutler, RB, Rosomoff, HL, Rosomoff, RS. Clonazepam open clinical treatment trial for myofascial syndrome associated chronic pain. Pain Med. 2000;1(4):332339.CrossRefGoogle ScholarPubMed
Harkins, S, Linford, J, Cohen, J, Kramer, T, Cueva, L. Administration of clonazepam in the treatment of TMD and associated myofascial pain: A double-blind pilot study. J Craniomandib Disord. 1991;5(3):179186.Google Scholar
Hersh, EV, Balasubramaniam, R, Pinto, A. Pharmacologic management of temporomandibular disorders. Oral Maxillofac Surg Clin North Am. 2008;20(2):197210.CrossRefGoogle ScholarPubMed
Leite, FM, Atallah, ÁN, El Dib, R et al. Cyclobenzaprine for the treatment of myofascial pain in adults. Cochrane Database Syst Rev. 2009;(3):CD006830. doi: 10.1002/14651858.CD006830.Google ScholarPubMed
Beebe, FA, Barkin, RL, Barkin, S. A clinical and pharmacologic review of skeletal muscle relaxants for musculoskeletal conditions. Am J Ther. 2005;12(2):151171.CrossRefGoogle ScholarPubMed
Ghanavatian, S, Derian, A. Tizanidine. StatPearls; 2018.Google Scholar
Shakespeare, D, Boggild, M, Young, CA. Anti-spasticity agents for multiple sclerosis. Cochrane Database Syst Rev. 2003;(4):CD001332. doi: 10.1002/14651858.CD006830.Google ScholarPubMed
Malanga, GA, Gwynn, MW, Smith, R, Miller, D. Tizanidine is effective in the treatment of myofascial pain syndrome. Pain Physician. 2002;5(4):422432.CrossRefGoogle ScholarPubMed
Groves, L, Shellenberger, MK, Davis, CS. Tizanidine treatment of spasticity: A meta-analysis of controlled, double-blind, comparative studies with baclofen and diazepam. Adv Ther. 1998;15(4):241251.Google ScholarPubMed
Malanga, G, Reiter, RD, Garay, E. Update on tizanidine for muscle spasticity and emerging indications. Expert Opin Pharmacother. 2008;9(12):22092215.CrossRefGoogle ScholarPubMed
Jaiswal, M, Sanyal, RP, Goswami, S. Revalidation of trigger point injection in myofascial pain syndrome, assessed by pain disability score. Int J Sci Study. 2017;172.Google Scholar
Xie, P, Qin, B, Yang, F et al. Lidocaine injection in the intramuscular innervation zone can effectively treat chronic neck pain caused by MTrPs in the trapezius muscle. Pain Physician. 2015;18(5):E815E826.Google ScholarPubMed
Firmani, M, Miralles, R, Casassus, R. Effect of lidocaine patches on upper trapezius EMG activity and pain intensity in patients with myofascial trigger points: A randomized clinical study. Acta Odontol Scand. 2015;73(3):210218.CrossRefGoogle ScholarPubMed
Affaitati, G, Fabrizio, A, Savini, A et al. A randomized, controlled study comparing a lidocaine patch, a placebo patch, and anesthetic injection for treatment of trigger points in patients with myofascial pain syndrome: Evaluation of pain and somatic pain thresholds. Clin Ther. 2009;31(4):705720.CrossRefGoogle Scholar
Affaitati, G, Costantini, R, Tana, C et al. Effects of topical vs. injection treatment of cervical myofascial trigger points on headache symptoms in migraine patients: A retrospective analysis. J Headache Pain. 2018;19(1):104. doi: 10.1186/s10194-018-0934-3.CrossRefGoogle ScholarPubMed
Borg-Stein, J, Simons, DG. Myofascial pain. Arch Phys Med Rehabil. 2002;83:S40S47.CrossRefGoogle ScholarPubMed
Awan, KH, Patil, S, Alamir, AWH et al. Botulinum toxin in the management of myofascial pain associated with temporomandibular dysfunction. J Oral Pathol Med. 2019;48(3):192200. doi: 10.1111/jop.12822.CrossRefGoogle ScholarPubMed
Machado, E, Machado, P, Wandscher, VF et al. A systematic review of different substance injection and dry needling for treatment of temporomandibular myofascial pain. Int J Oral Maxillofac Surg. 2018;47(11):14201432.CrossRefGoogle ScholarPubMed
Baker, JS, Nolan, PJ. Effectiveness of botulinum toxin type A for the treatment of chronic masticatory myofascial pain: A case series. J Am Dent Assoc. 2017;148(1):3339.CrossRefGoogle ScholarPubMed
Khalifeh, M, Mehta, K, Varguise, N, Suarez-Durall, P, Enciso, R. Botulinum toxin type A for the treatment of head and neck chronic myofascial pain syndrome. J Am Dent Assoc. 2016;147(12):959973.CrossRefGoogle ScholarPubMed
Kwanchuay, P, Petchnumsin, T, Yiemsiri, P et al. Efficacy and safety of single botulinum toxin type A (Botox®) injection for relief of upper trapezius myofascial trigger point: A randomized, double-blind, placebo-controlled study. J Med Assoc Thai. 2015;98(12):12311236.Google ScholarPubMed
Halder, GE, Scott, L, Wyman, A et al. Botox combined with myofascial release physical therapy as a treatment for myofascial pelvic pain. Investig Clin Urol. 2017;58(2):134139. doi: 10.4111/icu.2017.58.2.134.CrossRefGoogle ScholarPubMed

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