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Chapter 67 - Varicella in Pregnancy

from Section 11 - Infectious Conditions in Pregnancy

Published online by Cambridge University Press:  23 February 2023

By
Amira El-Messidi
Edited by
Amira El-Messidi  and
Alan D. Cameron
Amira El-Messidi
Affiliation:
McGill University, Montréal
Alan D. Cameron
Affiliation:
University of Glasgow
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Summary

A healthy 27-year-old G2P1 patient immigrated from Barbados last week. Her first appointment with you is in two days. She calls your office now concerned about her pregnancy, as her three-year-old son has chickenpox. She is currently at 15+2 weeks’ gestation by early dating sonography, which she had in her native country; routine prenatal investigations and aneuploidy screen were normal. Recent HIV testing was negative. She had a prior healthy pregnancy and term vaginal delivery.

Keywords

Varicella zoster virus, chickenpox, pregnancyAntenatal counseling, managementVaricella zoster immunoglobulin (VZIG), acyclovir, valacyclovirDiagnosisPerinatal risks, complications, maternal-fetal morbidity, adverse outcomeVaricella pneumonia, risk factors, treatmentFetal manifestations, sonography, anomaliesAntepartum, intrapartum managementMode of delivery
Type
Chapter
Information
OSCEs in Obstetrics and Maternal-Fetal Medicine
An Evidence-Based Approach
 , pp. 851 - 860
Publisher: Cambridge University Press
Print publication year: 2023

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References

Suggested Readings

Amirthalingam, G, Brown, K, Ramsay, M. Updated guidelines on postexposure prophylaxis (PEP) for varicella/shingles. Public Health England, June 2019.Google Scholar
An Advisory Committee Statement (ACS) National Advisory Committee on Immunization (NACI). Updated recommendations for the use of varicella zoster immune globulin (VarIg) for the prevention of varicella in at-risk patients. Public Health Agency of Canada, June 2016. Available at www.canada.ca/en/public-health/services/publications/healthy-living/updated-recommendations-use-varicella-zoster-immune-globulin-varig-prevention-varicella-risk-patients.html. Accessed September 13, 2020.Google Scholar
Centers for Disease Control and Prevention (CDC). Updated recommendations for use of VariZIG- United States, 2013. MMWR Morb Mortal Wkly Rep 2013; 62(28):574–576.Google Scholar
Center for Disease Control and Prevention (CDC). Varicella: epidemiology and prevention of vaccine-preventable diseases. In The Pink Book: Course Textbook, 13th ed. Available at www.cdc.gov/vaccines/pubs/pinkbook/varicella.html. Accessed September 13, 2020.Google Scholar
Hayward, K, Cline, A, Stephens, A, et al. Management of herpes zoster (shingles) during pregnancy. J Obstet Gynaecol. 2018;38(7):887–894.Google Scholar
Mandelbrot, L. Fetal varicella – diagnosis, management, and outcome. Prenat Diagn. 2012;32(6):511–518.CrossRefGoogle ScholarPubMed
Rafael, TJ. Varicella. Chapter 51 in Berghella, V, ed. Maternal-Fetal Evidence Based Guidelines. Boca Raton, FL: CRC Press; 2017.Google Scholar
Royal College of Obstetricians and Gynaecologists. Chickenpox in pregnancy. Green-Top Guideline No. 13, 2015. Available at www.rcog.org.uk/globalassets/documents/guidelines/gtg13.pdf. Accessed September 13, 2020.Google Scholar
Shrim, A, Koren, G, Yudin, MH, et al. No. 274 – management of varicella infection (chickenpox) in pregnancy. J Obstet Gynaecol Can. 2018 Aug;40(8):e652–e657.Google Scholar
Varicella. Chapter 34 in The Green Book. Public Health England, June 2019.Google Scholar

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