Skip to main content Accessibility help
×
Hostname: page-component-76fb5796d-zzh7m Total loading time: 0 Render date: 2024-04-27T10:38:47.768Z Has data issue: false hasContentIssue false

Section 9 - Hematologic Conditions in Pregnancy

Published online by Cambridge University Press:  23 February 2023

Amira El-Messidi
Affiliation:
McGill University, Montréal
Alan D. Cameron
Affiliation:
University of Glasgow
Get access

Summary

Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Chapter
Information
OSCEs in Obstetrics and Maternal-Fetal Medicine
An Evidence-Based Approach
, pp. 643 - 702
Publisher: Cambridge University Press
Print publication year: 2023

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Suggested Readings

ACOG Committee on Obstetrics. ACOG Practice Bulletin No. 78: hemoglobinopathies in pregnancy. Obstet Gynecol. 2007;109(1):229237.Google Scholar
Boga, C, Ozdogu, H. Pregnancy and sickle cell disease: A review of the current literature. Crit Rev Oncol Hematol. 2016;98:364374.CrossRefGoogle ScholarPubMed
Eissa, AA, tuck, SM. Sickle cell disease and β-thalassemia major in pregnancy. The Obstetrician and Gynaecologist 2013;15:7178.Google Scholar
Ezihe-Ejiofor, A, Jackson, J. Peripartum considerations in sickle cell disease. Curr Opin Anaesthesiol. 2021;34(3):212217.CrossRefGoogle ScholarPubMed
Green-Top Guideline. Management of Sickle Cell Disease in Pregnancy. London: Royal College of Obstetricians and Gynaecologists; 2011.Google Scholar
Howard, J, Oteng-Ntim, E. The obstetric management of sickle cell disease. Best Pract Res Clin Obstet Gynaecol. 2012;26(1):2536.CrossRefGoogle ScholarPubMed
Okusanya, BO, Oladapo, OT. Prophylactic versus selective blood transfusion for sickle cell disease in pregnancy. Cochrane Database Syst Rev. 2016;12(12):CD010378.Google Scholar
Oteng-Ntim, E, Meeks, D, Seed, PT, et al. Adverse maternal and perinatal outcomes in pregnant women with sickle cell disease: systematic review and meta-analysis. Blood. 2015;125(21):33163325.CrossRefGoogle ScholarPubMed
Patil, V, Ratnayake, G, Fastovets, G. Clinical ‘pearls’ of maternal critical care Part 2: sickle-cell disease in pregnancy. Curr Opin Anaesthesiol. 2017;30(3):326334.CrossRefGoogle ScholarPubMed
Smith-Whitley, K. Complications in pregnant women with sickle cell disease. Hematology Am Soc Hematol Educ Program. 2019;2019(1):359366.Google Scholar

Suggested Readings

American College of Obstetricians and Gynecologists’ Committee on Practice Bulletins–Obstetrics. ACOG Practice Bulletin No. 197: Inherited thrombophilias in pregnancy. Obstet Gynecol. 2018;132(1):e18e34. [Correction in Obstet Gynecol. 2018 Oct;132(4):1069]CrossRefGoogle Scholar
American College of Obstetricians and Gynecologists’ Committee on Practice Bulletins—Obstetrics. ACOG Practice Bulletin No. 196: Thromboembolism in Pregnancy. Obstet Gynecol. 2018;132(1):e1e17. [Correction in Obstet Gynecol. 2018 Oct;132(4):1068]CrossRefGoogle Scholar
Bates, SM, Rajasekhar, A, Middeldorp, S, et al. American Society of Hematology 2018 guidelines for management of venous thromboembolism: venous thromboembolism in the context of pregnancy. Blood Adv. 2018;2(22):33173359.CrossRefGoogle ScholarPubMed
Chan, WS, Rey, E, Kent, NE, et al. Venous thromboembolism and antithrombotic therapy in pregnancy. J Obstet Gynaecol Can. 2014;36(6):527553.CrossRefGoogle ScholarPubMed
Cohen, SL, Feizullayeva, C, McCandlish, JA, et al. Comparison of international societal guidelines for the diagnosis of suspected pulmonary embolism during pregnancy. Lancet Haematol. 2020;7(3):e247e258.CrossRefGoogle ScholarPubMed
Horlocker, TT, Vandermeuelen, E, Kopp, SL, et al. Regional anesthesia in the patient receiving antithrombotic or thrombolytic therapy: American Society of Regional Anesthesia and Pain Medicine Evidence-Based Guidelines (Fourth Edition). Reg Anesth Pain Med. 2018;43(3):263309. [Correction in Reg Anesth Pain Med. 2018 Jul;43(5):566]Google Scholar
Konstantinides, SV, Meyer, G, Becattini, C, et al. 2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS): The Task Force for the diagnosis and management of acute pulmonary embolism of the European Society of Cardiology (ESC). Eur Respir J. 2019;54(3):1901647.CrossRefGoogle Scholar
Leffert, L, Butwick, A, Carvalho, B, et al. The Society for Obstetric Anesthesia and Perinatology Consensus Statement on the anesthetic management of pregnant and postpartum women receiving thromboprophylaxis or higher dose anticoagulants. Anesth Analg. 2018;126(3):928944.Google Scholar
(a)Royal College of Obstetricians and Gynaecologists, Green-Top Guideline No. 37a. Reducing the risk of venous thromboembolism during pregnancy and the puerperium. April 2015. Available at www.rcog.org.uk/en/guidelines-research-services/guidelines/gtg37a/. Accessed March 19, 2021.Google Scholar
Royal College of Obstetricians and Gynaecologists, Green-Top Guideline No. 37b. Thrombotic disease in pregnancy and the puerperium: acute management. April 2015. Available at www.rcog.org.uk/en/guidelines-research-services/guidelines/gtg37b/. Accessed March 19, 2021.Google Scholar
van der Pol, LM, Tromeur, C, Bistervels, IM, et al. Pregnancy-adapted YEARS algorithm for diagnosis of suspected pulmonary embolism. N Engl J Med. 2019;380(12):11391149.CrossRefGoogle ScholarPubMed

Suggested Readings

Battinelli, EM. TTP and pregnancy. Blood. 2014;123(11):16241625.CrossRefGoogle ScholarPubMed
Fyfe-Brown, A, Clarke, G, Nerenberg, K, et al. Management of pregnancy-associated thrombotic thrombocytopenia purpura. AJP Rep. 2013;3(1):4550.CrossRefGoogle ScholarPubMed
Jiang, Y, McIntosh, JJ, Reese, JA, et al. Pregnancy outcomes following recovery from acquired thrombotic thrombocytopenic purpura. Blood. 2014;123(11):16741680.Google Scholar
Keiser, SD, Boyd, KW, Rehberg, JF, et al. A high LDH to AST ratio helps to differentiate pregnancy-associated thrombotic thrombocytopenic purpura (TTP) from HELLP syndrome. J Matern Fetal Neonatal Med. 2012;25(7):10591063.Google Scholar
Pourrat, O, Coudroy, R, Pierre, F. Differentiation between severe HELLP syndrome and thrombotic microangiopathy, thrombotic thrombocytopenic purpura and other imitators. Eur J Obstet Gynecol Reprod Biol. 2015;189:6872.CrossRefGoogle ScholarPubMed
Savignano, C, Rinaldi, C, De Angelis, V. Pregnancy associated thrombotic thrombocytopenic purpura: Practical issues for patient management. Transfus Apher Sci. 2015;53(3):262268.CrossRefGoogle ScholarPubMed
Scully, M, Thomas, M, Underwood, M, et al. Thrombotic thrombocytopenic purpura and pregnancy: presentation, management, and subsequent pregnancy outcomes. Blood. 2014;124(2):211219.CrossRefGoogle ScholarPubMed
Vesely, SK. Life after acquired thrombotic thrombocytopenic purpura: morbidity, mortality, and risks during pregnancy. J Thromb Haemost. 2015;13(Suppl 1):S216S222.CrossRefGoogle ScholarPubMed
von Auer, C, von Krogh, AS, Kremer Hovinga, JA, et al. Current insights into thrombotic microangiopathies: thrombotic thrombocytopenic purpura and pregnancy. Thromb Res. 2015;135(Suppl 1):S30S33.CrossRefGoogle ScholarPubMed
Zheng, XL, Vesely, SK, Cataland, SR, et al. ISTH guidelines for treatment of thrombotic thrombocytopenic purpura. J Thromb Haemost. 2020;18(10):24962502.CrossRefGoogle ScholarPubMed

Suggested Readings

ACOG Practice Bulletin No. 207: Thrombocytopenia in pregnancy. Obstet Gynecol. 2019;133(3):e181–e193.CrossRefGoogle Scholar
Baucom, AM, Kuller, JA, Dotters-Katz, S. Immune thrombocytopenic purpura in pregnancy. Obstet Gynecol Surv. 2019;74(8):490496.Google Scholar
Care, A, Pavord, S, Knight, M, et al. Severe primary autoimmune thrombocytopenia in pregnancy: a national cohort study. BJOG. 2018;125(5):604612.CrossRefGoogle ScholarPubMed
Cines, DB, Levine, LD. Thrombocytopenia in pregnancy. Hematology Am Soc Hematol Educ Program. 2017;2017(1):144151.CrossRefGoogle ScholarPubMed
Fogerty, AE. Thrombocytopenia in pregnancy: approach to diagnosis and management. Semin Thromb Hemost. 2020;46(3):256263.Google Scholar
Gernsheimer, T, James, AH, Stasi, R. How I treat thrombocytopenia. Blood 2013;121(1):3847.CrossRefGoogle Scholar
Eslick, R, McLintock, C. Managing ITP and thrombocytopenia in pregnancy. Platelets. 2020;31(3):300306.Google Scholar
Goldman, BG, Hehir, MP, Yambasu, S, et al. The presentation and management of platelet disorders in pregnancy. Eur J Haematol. 2018;100(6):560566.CrossRefGoogle ScholarPubMed
Pishko, AM, Levine, LD, Cines, DB. Thrombocytopenia in pregnancy: Diagnosis and approach to management. Blood Rev. 2020;40:100638.CrossRefGoogle ScholarPubMed
Provan, D, Arnold, DM, Bussel, JB, et al. Updated international consensus report on the investigation and management of primary immune thrombocytopenia. Blood Adv. 2019;3(22):37803817.Google Scholar

Save book to Kindle

To save this book to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×