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  • Print publication year: 2021
  • Online publication date: April 2021

Chapter 2 - Standard Semen Analysis: Computer-Assisted Semen Analysis


Computer-assisted semen analysis (CASA) is an automated and objective method to evaluate several sperm parameters, either in conjunction with or instead of routine manual semen analysis. CASA systems have undergone a complete metamorphosis since the initial systems were developed to track sperm motion four decades ago [see 1, 2 for detailed history]. Various innovations in bioengineering, software algorithms and computational power have led to more than 14 CASA systems (Figure 2.1) currently available across the globe for commercial use in evaluating both human and animal spermatozoa [3, 4, 5]. Although CASA was initially introduced as a research tool and not commonly used for semen analysis in the clinical setting [1], more and more fertility clinics are investing in and switching to automated systems.

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