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Chapter 25 - Future Developments: Sperm Proteomics

Published online by Cambridge University Press:  05 April 2021

By
Manesh Panner ,
Selvam Kumar ,
Saradha Baskaran  and
Ashok Agarwal
Edited by
Ashok Agarwal ,
Ralf Henkel  and
Ahmad Majzoub
Ashok Agarwal
Affiliation:
The Cleveland Clinic Foundation, Cleveland, OH
Ralf Henkel
Affiliation:
University of the Western Cape, South Africa
Ahmad Majzoub
Affiliation:
Hamad Medical Corporation, Doha
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Summary

Spermatozoa are mature male gametes that are produced in the testes of a healthy man by spermatogenesis, with further maturation of sperm taking place during their transit through the epididymis. In the human, approximately 20 to 240 million sperm are produced per day [1]. Unlike other somatic cells present in the human body, spermatozoa contain a head, neck, mid-piece and tail region. The head region contains the genetic material which is transferred to the oocyte during the fertilization process. Apart from DNA, spermatozoa also deliver additional subcellular materials such as oocyte activating factors, RNA, microRNAs and exosomal proteins that are essential for the development of the oocyte into a zygote.

Type
Chapter
Information
Manual of Sperm Function Testing in Human Assisted Reproduction , pp. 245 - 255
Publisher: Cambridge University Press
Print publication year: 2021

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